Search Results - "KONISHI, Masaaki"

High cell density cultivation of Corynebacterium glutamicum by deep learning-assisted medium design and the subsequent feeding strategy by Konishi, Masaaki

“…To improve the cell productivity of Corynebacterium glutamicum, its initial specific growth rate was improved by medium improvement using deep neural network…”
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Bioethanol production estimated from volatile compositions in hydrolysates of lignocellulosic biomass by deep learning by Konishi, Masaaki

“…The cell growth and ethanol production from hydrolysates of various types were estimated from the volatile composition of lignocellulosic biomass by deep…”
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Scoring the physical frailty phenotype of patients with heart failure by Konishi, Masaaki

“…[...]it is often difficult for clinicians to determine the presence or absence of shrinkage or weight loss, another important phenotype of physical frailty, in…”
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Relationship Between Thickness of Calcium on Optical Coherence Tomography and Crack Formation After Balloon Dilatation in Calcified Plaque Requiring Rotational Atherectomy by Maejima, Nobuhiko, Hibi, Kiyoshi, Saka, Kenichiro, Akiyama, Eiichi, Konishi, Masaaki, Endo, Mitsuaki, Iwahashi, Noriaki, Tsukahara, Kengo, Kosuge, Masami, Ebina, Toshiaki, Umemura, Satoshi, Kimura, Kazuo

“…Background:Target lesion calcification is known to influence percutaneous coronary intervention. We evaluated the effects of rotational atherectomy (RA) and…”
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High throughput optimization of medium composition for Escherichia coli protein expression using deep learning and Bayesian optimization by Yoshida, Kanako, Watanabe, Kazuki, Chiou, Tai-Ying, Konishi, Masaaki

“…To improve synthetic media for protein expression in Escherichia coli, a strategy using deep neural networks (DNN) and Bayesian optimization was performed in…”
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Selective production of deacetylated mannosylerythritol lipid, MEL-D, by acetyltransferase disruption mutant of Pseudozyma hubeiensis by Konishi, Masaaki, Makino, Motoki

“…Mannosylerythritol lipids (MELs) are produced by several smut fungi of the Ustilaginaceae family; they are promising microbial biosurfactants and have…”
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Estimating effects of yeast extract compositions on Escherichia coli growth by a metabolomics approach by Tachibana, Seiga, Watanabe, Kazuki, Konishi, Masaaki

“…Bioprocess stability depends on the variety of yeast extract, which varies from lot-to-lots and between brands, thereby leading to variable bacterial growth…”
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Artificial intelligence-assisted analysis reveals amino acid effects and interactions on Limosilactobacillus fermentum growth by Kobayashi, Yoshimi, Chiou, Tai-Ying, Konishi, Masaaki

“…ABSTRACT To understand the growth of lactic acid bacteria (LAB), Limosilactobacillus fermentum, in response to medium compositions, a deep neural network (DNN)…”
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Renin-angiotensin system inhibitors and the severity of coronavirus disease 2019 in Kanagawa, Japan: a retrospective cohort study by Matsuzawa, Yasushi, Ogawa, Hisao, Kimura, Kazuo, Konishi, Masaaki, Kirigaya, Jin, Fukui, Kazuki, Tsukahara, Kengo, Shimizu, Hiroyuki, Iwabuchi, Keisuke, Yamada, Yu, Saka, Kenichiro, Takeuchi, Ichiro, Hirano, Toshio, Tamura, Kouichi

“…Since the beginning of the coronavirus disease 2019 (COVID-19) outbreak initiated on the Diamond Princess Cruise Ship at Yokohama harbor in February 2020, we…”
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In-Hospital Mortality in Acute Myocardial Infarction According to Population Density and Primary Angioplasty Procedures Volume by Matsuzawa, Yasushi, Konishi, Masaaki, Nakai, Michikazu, Saigusa, Yusuke, Taguri, Masataka, Gohbara, Masaomi, Ebina, Toshiaki, Kosuge, Masami, Hibi, Kiyoshi, Nishimura, Kunihiro, Miyamoto, Yoshihiro, Yasuda, Satoshi, Ogawa, Hisao, Saito, Yoshihiko, Nakayama, Naoki, Takeuchi, Ichiro, Tamura, Kouichi, Kimura, Kazuo

“…Background:Low population density may be associated with high mortality in acute myocardial infarction (AMI) patients. The purpose of this study was to…”
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Aspartate aminotransferase to alanine aminotransferase ratio is associated with frailty and mortality in older patients with heart failure by Maeda, Daichi, Kagiyama, Nobuyuki, Jujo, Kentaro, Saito, Kazuya, Kamiya, Kentaro, Saito, Hiroshi, Ogasahara, Yuki, Maekawa, Emi, Konishi, Masaaki, Kitai, Takeshi, Iwata, Kentaro, Wada, Hiroshi, Hiki, Masaru, Dotare, Taishi, Sunayama, Tsutomu, Kasai, Takatoshi, Nagamatsu, Hirofumi, Ozawa, Tetsuya, Izawa, Katsuya, Yamamoto, Shuhei, Aizawa, Naoki, Yonezawa, Ryusuke, Oka, Kazuhiro, Momomura, Shin-ichi, Matsue, Yuya

“…Frailty is a common comorbidity associated with adverse events in patients with heart failure, and early recognition is key to improving its management. We…”
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Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure　― Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF) by Konishi, Masaaki, Ebner, Nicole, Springer, Jochen, Schefold, Joerg C., Doehner, Wolfram, Dschietzig, Thomas Bernd, Anker, Stefan D., Haehling, Stephan von

“…Background:Kynurenine is a circulating metabolite from the essential amino acid tryptophan. Accelerated degradation of kynurenine in skeletal muscle has been…”
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The need for re-defining cut-off values in heart failure: From obesity to iron deficiency by Konishi, Masaaki, von Haehling, Stephan

“…The health status of older people is frequently complicated by one or more chronic diseases. Some conditions might have a different meaning in certain groups…”
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Association Between Gait Speed as a Measure of Frailty and Risk of Cardiovascular Events After Myocardial Infarction by Matsuzawa, Yasushi, MD, Konishi, Masaaki, MD, PhD, Akiyama, Eiichi, MD, Suzuki, Hiroyuki, MD, Nakayama, Naoki, MD, PhD, Kiyokuni, Masayoshi, MD, PhD, Sumita, Shinichi, MD, PhD, Ebina, Toshiaki, MD, PhD, Kosuge, Masami, MD, PhD, Hibi, Kiyoshi, MD, PhD, Tsukahara, Kengo, MD, PhD, Iwahashi, Noriaki, MD, PhD, Endo, Mitsuaki, MD, PhD, Maejima, Nobuhiko, MD, Saka, Kenichiro, MD, Hashiba, Katsutaka, MD, Okada, Kozo, MD, Taguri, Masataka, PhD, Morita, Satoshi, PhD, Sugiyama, Seigo, MD, PhD, Ogawa, Hisao, MD, PhD, Sashika, Hironobu, MD, PhD, Umemura, Satoshi, MD, PhD, Kimura, Kazuo, MD, PhD

“…Objectives This study sought to determine the additional clinical value of gait speed to Framingham risk score (FRS), cardiac function, and comorbid conditions…”
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Decreased Appendicular Skeletal Muscle Mass is Associated with Poor Outcomes after ST-Segment Elevation Myocardial Infarction by Sato, Ryosuke, Akiyama, Eiichi, Konishi, Masaaki, Matsuzawa, Yasushi, Suzuki, Hiroyuki, Kawashima, Chika, Kimura, Yuichiro, Okada, Kozo, Maejima, Nobuhiko, Iwahashi, Noriaki, Hibi, Kiyoshi, Kosuge, Masami, Ebina, Toshiaki, Haehling, Stephan von, Anker, Stefan D., Tamura, Kouichi, Kimura, Kazuo

“…Aim: The importance of sarcopenia in cardiovascular diseases has been recently demonstrated. This study aims to examine whether skeletal muscle mass (SMM), an…”
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Efficient production of sophorolipids by Starmerella bombicola using a corncob hydrolysate medium by Konishi, Masaaki, Yoshida, Yuka, Horiuchi, Jun-ichi

“…Sophorolipids (SLs) are amphiphilic compounds produced from a variety of saccharides and vegetable oils by the yeast Starmerella bombicola and related strains,…”
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Impact of Low-Density Lipoprotein Cholesterol Levels at Acute Coronary Syndrome Admission on Long-Term Clinical Outcomes by Sato, Ryosuke, Matsuzawa, Yasushi, Yoshii, Tomohiro, Akiyama, Eiichi, Konishi, Masaaki, Nakahashi, Hidefumi, Minamimoto, Yugo, Kimura, Yuichiro, Okada, Kozo, Maejima, Nobuhiko, Iwahashi, Noriaki, Kosuge, Masami, Ebina, Toshiaki, Kimura, Kazuo, Tamura, Kouichi, Hibi, Kiyoshi

“…Aim: Low-density lipoprotein cholesterol (LDL-C) level reduction is highly effective in preventing the occurrence of a cardiovascular event. Contrariwise, an…”
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Digital Assessment of Endothelial Function and Ischemic Heart Disease in Women by Matsuzawa, Yasushi, MD, Sugiyama, Seigo, MD, PhD, Sugamura, Koichi, MD, PhD, Nozaki, Toshimitsu, MD, Ohba, Keisuke, MD, Konishi, Masaaki, MD, Matsubara, Junichi, MD, Sumida, Hitoshi, MD, PhD, Kaikita, Koichi, MD, PhD, Kojima, Sunao, MD, PhD, Nagayoshi, Yasuhiro, MD, PhD, Yamamuro, Megumi, MD, PhD, Izumiya, Yasuhiro, MD, PhD, Iwashita, Satomi, MT, Matsui, Kunihiko, MD, PhD, Jinnouchi, Hideaki, MD, PhD, Kimura, Kazuo, MD, PhD, Umemura, Satoshi, MD, PhD, Ogawa, Hisao, MD, PhD

“…Objectives We investigated the utility of digital reactive hyperemia peripheral arterial tonometry (RH-PAT) in predicting ischemic heart disease (IHD),…”
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Incremental Prognostic Significance of Peripheral Endothelial Dysfunction in Patients With Heart Failure With Normal Left Ventricular Ejection Fraction by Akiyama, Eiichi, MD, Sugiyama, Seigo, MD, PhD, Matsuzawa, Yasushi, MD, Konishi, Masaaki, MD, PhD, Suzuki, Hiroyuki, MD, Nozaki, Toshimitsu, MD, PhD, Ohba, Keisuke, MD, Matsubara, Junichi, MD, PhD, Maeda, Hirofumi, MD, Horibata, Yoko, MD, Sakamoto, Kenji, MD, PhD, Sugamura, Koichi, MD, PhD, Yamamuro, Megumi, MD, PhD, Sumida, Hitoshi, MD, PhD, Kaikita, Koichi, MD, PhD, Iwashita, Satomi, MT, Matsui, Kunihiko, MD, MPH, Kimura, Kazuo, MD, PhD, Umemura, Satoshi, MD, PhD, Ogawa, Hisao, MD, PhD

“…Objectives The purpose of this study was to investigate whether peripheral endothelial dysfunction could predict the occurrence of cardiovascular events in…”
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Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI by Matsuzawa, Yasushi, Nakahashi, Hidefumi, Konishi, Masaaki, Sato, Ryosuke, Kawashima, Chika, Kikuchi, Shinnosuke, Akiyama, Eiichi, Iwahashi, Noriaki, Maejima, Nobuhiko, Okada, Kozo, Ebina, Toshiaki, Hibi, Kiyoshi, Kosuge, Masami, Ishigami, Tomoaki, Tamura, Kouichi, Kimura, Kazuo

“…Trimethylamine N-oxide (TMAO), a metabolite derived from the gut microbiota, is proatherogenic and associated with cardiovascular events. However, the change…”
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