Search Results - "KONG, PHILIP L."

Endogenous activation of adaptive immunity: Tenascin-C drives interleukin-17 synthesis in murine arthritic joint disease by Ruhmann, Michaela, Piccinini, Anna M., Kong, Philip L., Midwood, Kim S.

“…Objective Rheumatoid arthritis is characterized by persistent synovial inflammation and progressive joint destruction, which are mediated by innate and…”
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An Antibody Against Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) Dampens Proinflammatory Cytokine Secretion by Lamina Propria Cells from Patients with IBD by Brynjolfsson, Siggeir F, Magnusson, Maria K, Kong, Philip L, Jensen, Teis, Kuijper, Joseph L, Håkansson, Katarina, Read, Christine B, Stennicke, Vibeke W, Sjövall, Henrik, Jo Wick, Mary

“…Triggering receptor expressed on myeloid cells 1 (TREM-1) is a potent amplifier of inflammation. Recently, the antimicrobial peptide PGLYRP-1 was shown to be…”
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Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells by MOUNTJOY, KATHLEEN G, KONG, PHILIP L, TAYLOR, JOHN A, WILLARD, DERRIL H, WILKISON, WILLIAM O

“…1 Research Centre for Developmental Medicine and Biology, Department of Paediatrics 2 School of Biological Sciences, University of Auckland, Auckland 1, New…”
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Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis by Drexler, Stefan K, Kong, Philip L, Wales, Jeremy, Foxwell, Brian M

“…Rheumatoid arthritis is a multisystemic auto-inflammatory disease affecting up to 1% of the population and leading to the destruction of the joints. Evidence…”
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Detection of a secreted metalloprotease within the nuclei of liver cells by Hunt, Ryan C, Geetha, S, Allen, Courtni E, Hershko, Klilah, Fathke, Robert, Kong, Philip L, Plum, Elizabeth, Struble, Evi Budo, Soejima, Kenji, Friedman, Scott, Garfield, Susan, Balaji, S, Kimchi-Sarfaty, Chava

“…ADAMTS13 is a secreted zinc metalloprotease expressed by various cell types. Here, we investigate its cellular pathway in endogenously expressing liver cell…”
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The Centromeric Region of Chromosome 7 from MRL Mice (Lmb3) Is an Epistatic Modifier of Fas for Autoimmune Disease Expression by Kong, Philip L, Morel, Laurence, Croker, Byron P, Craft, Joseph

“…Lupus is a prototypic systemic autoimmune disease that has a significant genetic component in its etiology. Several genome-wide screens have identified…”
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Intrinsic T Cell Defects in Systemic Autoimmunity by KONG, PHILIP L., ODEGARD, JARED M., BOUZAHZAH, FARIDA, CHOI, JIN-YOUNG, EARDLEY, LEAH D., ZIELINSKI, CHRISTINA E., CRAFT, JOSEPH E.

“…: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of T cell tolerance to nuclear antigens. Studies in mice and humans have…”
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Oxazolone and diclofenac-induced popliteal lymph node assay reactions are attenuated in mice orally pretreated with the respective compound: potential role for the induction of regulatory mechanisms following enteric administration by Gutting, Bradford W, Bouzahzah, Farida, Kong, Philip L, Updyke, Lawrence W, Amacher, David E, Craft, Joe

“…The murine popliteal lymph node assay (PLNA) was examined as a preclinical assay with the potential to identify low-molecular-weight compounds (LMWCs) that are…”
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ENU-based phenotype-driven screening by Ripoll, Vera M, Kong, Philip L, Potter, Paul K

“…Deciphering the contribution of individual genes and in turn pathways to cellular processes can be complicated and is often based on prior knowledge or…”
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Role of the H‐2 haplotype in Fas‐intact lupus‐prone MRL mice: association with autoantibodies but not renal disease by Kong, Philip L., Zhu, Tongping, Madaio, Michael P., Craft, Joseph

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