Search Results - "KONDO, Shunya"
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Generation and characterization of a mouse line carrying Reck‐CreERT2 knock‐in allele
Published in Genesis (New York, N.Y. : 2000) (01-04-2018)“…Reck encodes a membrane‐anchored glycoprotein implicated in the regulation of extracellular metalloproteinases, Notch‐signaling, and Wnt7‐signaling and shown…”
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The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis
Published in Cell (14-12-2001)“…Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling. We previously found that a membrane-anchored glycoprotein, RECK,…”
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Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice
Published in Oncogene (24-06-2004)“…The matrix metalloproteinase (MMP) family (approximately 25 members in mammals) has been implicated in extracellular matrix remodeling associated with…”
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Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development
Published in PloS one (01-04-2014)“…Memo is a conserved protein that was identified as an essential mediator of tumor cell motility induced by receptor tyrosine kinase activation. Here we show…”
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RECK: a novel suppressor of malignancy linking oncogenic signaling to extracellular matrix remodeling
Published in Cancer and metastasis reviews (01-06-2003)“…RECK was first isolated as a transformation suppressor gene by cDNA expression cloning in a mouse fibroblast cell line transformed by an activated RAS…”
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The Membrane-Anchored Matrix Metalloproteinase (MMP) Regulator RECK in Combination with MMP-9 Serves as an Informative Prognostic Indicator for Colorectal Cancer
Published in Clinical cancer research (15-08-2004)“…Purpose: RECK , a membrane-anchored regulator of matrix metalloproteinases (MMPs), is widely expressed in healthy tissue, whereas it is expressed at lower…”
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The membrane-anchored MMP-regulator RECK is a target of myogenic regulatory factors
Published in Oncogene (01-09-2005)“…The membrane-anchored MMP-regulator RECK is down regulated in many solid tumors; the extent of RECK down regulation correlates with poor prognosis. Forced…”
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Dual effects of the membrane-anchored MMP regulator RECK on chondrogenic differentiation of ATDC5 cells
Published in Journal of cell science (01-03-2007)“…Extracellular matrix (ECM) undergoes continuous remodeling during mammalian development. Although involvement of matrix metalloproteinases (MMPs) in ECM…”
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Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice
Published in BMC developmental biology (06-08-2010)“…Developmental angiogenesis proceeds through multiple morphogenetic events including sprouting, intussusception, and pruning. Mice lacking the membrane-anchored…”
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Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells
Published in Journal of bone and mineral metabolism (01-11-2010)“…Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are bioactive lysophospholipids that affect various cellular processes through G protein-coupled…”
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Radial basis function neural network based PID control for quad-rotor flying robot
Published in 2017 17th International Conference on Control, Automation and Systems (ICCAS) (01-10-2017)“…It is difficult for flying robots with a conventional PID controller to fly stably with external disturbances such as wind. Thus, a flight control method that…”
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Conference Proceeding -
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Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages
Published in Oncotarget (13-12-2016)“…The extracellular serine protease inhibitor serpinE2 is overexpressed in breast cancer and has been shown to foster metastatic spread. Here, we investigated…”
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Electrostatic Interaction between Cytochrome P450 and NADPH-P450 Reductase: Comparison of Mixed and Fused Systems Consisting of Rat Cytochrome P450 1A1 and Yeast NADPH-P450 Reductase
Published in Biochemical and biophysical research communications (13-04-1999)“…The electrostatic interaction between rat cytochrome P450 1A1 and yeast NADPH-P450 reductase was analyzed by using recombinant yeast microsomes containing both…”
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Inhibitory Effects of Vitamin A and Vitamin K on Rat Cytochrome P4501A1-Dependent Monooxygenase Activity
Published in Biochemical and biophysical research communications (27-08-1999)“…The inhibitory effects of vitamins A and K toward P4501A1-dependent 7-ethoxycoumarin O-deethylation were examined in the reconstituted system containing the…”
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Inhibitory Effects of Detergents on Rat CYP1A1-Dependent Monooxygenase: Comparison of Mixed and Fused Systems Consisting of Rat CYP 1A1 and Yeast NADPH-P450 Reductase
Published in Biochemical and biophysical research communications (09-02-2001)“…Inhibitory effects of detergents Triton X-100 and Chaps on 7-ethoxycoumarin O-deethylation activity were examined in the recombinant microsomes containing both…”
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Journal Article