Search Results - "KONDA, Mikihiko"

Synthesis and Biological Evaluation of Alkyl, Alkoxy, Alkylthio, or Amino-Substituted 2, 3-Dihydro-1, 5-benzothiazepin-4(5H)-ones by INOUE, Hirozumi, KONDA, Mikihiko, HASHIYAMA, Tomiki, OTSUKA, Hisao, WATANABE, AKishige, GAINO, Mitsunori, TAKAHASHI, Kaoru, DATE, Tadamasa, OKAMURA, Kimio, TAKEDA, Mikio, NARITA, Hiroshi, MURATA, Sakae, ODAWARA, AKio, SASAKI, Haruhiko, NAGAO, Taku

“…2, 3-Dihydro-1, 5-benzothiazepin-4(5H)-ones substituted with an alkyl, alkoxy, alkylthio, hydroxy, or amino group on the fused benzene ring of the 1,…”
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Synthesis of 1, 5-Benzothiazepine Derivatives. III by KUGITA, HIROSHI, INOUE, HIROZUMI, IKEZAKI, MUNEYOSHI, KONDA, MIKIHIKO, TAKEO, SATOSHI

“…Various derivatives of 2-aryl-3-hydroxy-2, 3-dihydro-1, 5-benzothiazepin-4 (5H)-one (I) were synthesized. Alternative routes to…”
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Amino Acids and Peptides. XXIII. An Asymmetric Synthesis of (R)-(-)-Laudanosine from L-3-(3, 4-Dihydroxyphenyl) alanine by KONDA, MIKIHIKO, OHISHI, TOKURO, YAMADA, SHUNICHI

“…Following the previous asymmetric syntheses of (S)-(+)-laudanosine (V) and (S)-(+)-reticuline (VI) from L-3-(3, 4-dihydroxyphenyl) alanine (L-DOPA),…”
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Synthesis of 2-Phenylthiazolidine Derivatives as Cardiotonic Agents. IV. Modification of the Phenylpiperazino Moiety of 2- (Phenylpiperazino-alkoxyphenyl) thiazolidine-3-carbothioamides and the Corresponding Carboxamides by NATE, HIROYUKI, WATANABE, AKISHIGE, MATSUKI, KENJI, INOUE, ISAO, OHTSUKA, HISAO, SEKINE, YASUO, ODA, KUNIYUKI, HONMA, YASUSHI, ISHIDA, AKIHIKO, KANNO, TAKESHI, KONDA, MIKIHIKO, NAKAI, HIDEO, WADA, HIROSHI, TAKEDA, MIKIO, YABANA, HIDEO, NAGAO, TAKU

“…Examination of the structure-activity relationships of 2- (phenylpiperazinoalkoxyphenyl) -thiazolidine-3-carbothioamides and the corresponding carboxamides (1)…”
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Amino Acids and Peptides. XVII. A Biogenetic-type, Asymmetric Synthesis of (S)-Laudanosine from L-3-(3, 4-Dihydroxyphenyl) alanine by 1, 3-Transfer of Asymmetry by KONDA, MIKIHIKO, SHIOIRI, TAKAYUKI, YAMADA, SHUNICHI

“…The asymmetric synthesis of a representative benzylisoquinoline alkaloid, (S)-(+)-laudanosine (III) was accomplished by means of the biogenetic-type,…”
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Amino Acids and Peptides. XVIII. A Biogenetic-type, Asymmetric Synthesis of (S)-Reticuline from L-3-(3, 4-Dihydroxyphenyl)-alanine by 1, 3-Transfer of Asymmetry by KONDA, MIKIHIKO, SHIOIRI, TAKAYUKI, YAMADA, SHUNICHI

“…The asymmetric synthesis of (S)-reticuline (I) was accomplished by means of the biogenetic-type, asymmetric Pictet-Spengler reaction of…”
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Synthesis of 1, 5-Benzothiazepine Derivatives. II by KUGITA, HIROSHI, INOUE, HIROZUMI, IKEZAKI, MUNEYOSHI, KONDA, MIKIHIKO, TAKEO, SATOSHI

“…Threo-2-hydroxy-3-aryl-(2-nitroarylthio) propionates (III-β) were obtained by the reaction of 2-nitrothiophenols (I) and arylglycidic esters (II) in the…”
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Synthesis of halogen-substituted 1,5-benzothiazepine derivatives and their vasodilating and hypotensive activities by Inoue, Hirozumi, Konda, Mikihiko, Hashiyama, Tomiki, Otsuka, Hisao, Takahashi, Kaoru, Gaino, Mitsunori, Date, Tadamasa, Aoe, Keiichi, Takeda, Mikio

“…In an attempt to improve the effectiveness and duration of the action of diltiazem (1), a 1,5-benzothiazepine calcium channel blocker, its derivatives (2) with…”
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Reaction of 3-Phenylglycidic Esters. III. Reaction of cis-3-Arylglycidic Esters with Various Thiophenols by HASHIYAMA, TOMIKI, INOUE, HIROZUMI, KONDA, MIKIHIKO, TAKEDA, MIKIO

“…The reaction of the cis-3-arylglycidic esters 2 and 10 with thiophenols (3) has been investigated. The reactivity and stereoselectivity of the oxirane…”
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Improved synthesis of a 9-oxo-6,7-benzomorphan and its homolog. Novel rearrangement of heterocyclic enamines via bromination by Takeda, Mikio, Inoue, Hirozumi, Konda, Mikihiko, Saito, Seiichi, Kugita, Hiroshi

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Reaction of 3-Phenylglycidic Esters. IV. Reaction of Methyl 3-(4-Methoxyphenyl) glycidate with 2-Nitrophenol and Synthesis of 1, 5-Benzoxazepine Derivatives by HASHIYAMA, TOMIKI, WATANABE, AKISHIGE, INOUE, HIROZUMI, KONDA, MIKIHIKO, TAKEDA, MIKIO, MURATA, SAKAE, NAGAO, TAKU

“…The reaction of methyl trans-3-(4-methoxyphenyl) glycidate (1) with 2-nitrophenol was investigated under various conditions. Generally, the reaction proceeded…”
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Hydrogenated benzo[f]quinolines and benz[e]indoles as analgetics. 1 by Takeda, Mikio, Konda, Mikihiko, Honma, Yasushi, Inoue, Hirozumi, Saito, Seiichi, Kugita, Hiroshi, Nurimoto, Seiichi, Hayashi, Goro

“…A series of octahydrobenzo[f]quinolines(IIIa) and hexahydro-1H-benz[e]indoles(IIIb), rigid structures related to 3-phenylpiperidine and pyrrolidine analgetics,…”
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