Search Results - "KOMIYAMA, Kazuo"

Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation by Shimba, Shigeki, Ogawa, Tomohiro, Hitosugi, Shunsuke, Ichihashi, Yuya, Nakadaira, Yuki, Kobayashi, Munehiro, Tezuka, Masakatsu, Kosuge, Yasuhiro, Ishige, Kumiko, Ito, Yoshihisa, Komiyama, Kazuo, Okamatsu-Ogura, Yuko, Kimura, Kazuhiro, Saito, Masayuki

“…A link between circadian rhythm and metabolism has long been discussed. Circadian rhythm is controlled by positive and negative transcriptional and…”
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Polymeric immunoglobulin receptor by Asano, Masatake, Komiyama, Kazuo

“…The surface of mucosal sites, such as the intestinal tract, are covered by epithelial cells. To protect the intestinal environment from invading pathogens and…”
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Maximum Occlusal Force and Physical Performance in the Oldest Old: The Tokyo Oldest Old Survey on Total Health by Iinuma, Toshimitsu, Arai, Yasumichi, Fukumoto, Motoko, Takayama, Michiyo, Abe, Yukiko, Asakura, Keiko, Nishiwaki, Yuji, Takebayashi, Toru, Iwase, Takashi, Komiyama, Kazuo, Gionhaku, Nobuhito, Hirose, Nobuyoshi

“…Objectives To elucidate the independent relationship between masticatory and physical performance in community‐living oldest old people (mean age ± standard…”
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SLPI facilitates cell migration by regulating lamellipodia/ruffles and desmosomes, in which Galectin4 plays an important role by Mizutani, Yusuke, Omagari, Daisuke, Hayatsu, Manabu, Nameta, Masaaki, Komiyama, Kazuo, Mikami, Yoshikazu, Ushiki, Tatsuo

“…To elucidate the underlying mechanism of secretory leukocyte protease inhibitor (SLPI)-induced cell migration, we compared SLPI-deleted human gingival…”
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Loop-mediated isothermal amplification combined with PCR and immunohistochemistry for detecting Porphyromonas gingivalis in periapical periodontitis by Kitano, Taiichi, Mikami, Yoshikazu, Iwase, Takashi, Asano, Masatake, Komiyama, Kazuo

“…Porphyromonas gingivalis is important in the development of marginal periodontitis. However, the precise role and localization of P. gingivalis in chronic…”
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Human uterus myoma and gene expression profiling: A novel in vitro model for studying secretory leukocyte protease inhibitor-mediated tumor invasion by Mikami, Yoshikazu, Fukushima, Atsushi, Komiyama, Yusuke, Iwase, Takashi, Tsuda, Hiromasa, Higuchi, Yasuhiko, Hayakawa, Satoshi, Kuyama, Kayo, Komiyama, Kazuo

“…Highlights • The myoma model provides a biologically relevant matrix for tumor invasion studies. • Ca9-22 but not SLPI-deficient Ca9-22 cells invade into myoma…”
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Relationship between appearance of tongue carcinoma on intraoral ultrasonography and histopathologic findings by Shinozaki, Yasuhisa, DDS, Jinbu, Yoshinori, DDS, PhD, Ito, Hiroto, DDS, PhD, Noguchi, Tadahide, DDS, PhD, Kusama, Mikio, DDS, PhD, Matsumoto, Naoyuki, DDS, PhD, Komiyama, Kazuo, DDS, PhD, Taniguchi, Nobuyuki, DDS, PhD

“…Objective To clarify whether intraoral ultrasonography (I-US) is effective for predicting metastasis of tongue cancer to the cervical lymph nodes. Study Design…”
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Osteocytes up-regulate the terminal differentiation of pre-osteoblasts via gap junctions by Nishikawa, Yoichi, Akiyama, Yuko, Yamamoto, Kiyofumi, Kobayashi, Masayuki, Watanabe, Eri, Watanabe, Nobukazu, Shimizu, Noriyoshi, Mikami, Yoshikazu, Komiyama, Kazuo

“…•We examined cell-to-cell interaction between pre-osteoblasts and osteocytes.•ALP and BSP expression in pre-osteoblasts co-cultured with osteocytes was…”
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Satisfaction with dietary life affects oral health-related quality of life and subjective well-being in very elderly people by Iinuma, Toshimitsu, Arai, Yasumichi, Takayama, Midori, Takayama, Michiyo, Abe, Yukiko, Osawa, Yusuke, Fukumoto, Motoko, Fukui, Yusuke, Shioda, Yohei, Hirose, Nobuyoshi, Komiyama, Kazuo, Gionhaku, Nobuhito

“…Age-related deterioration in physical and oral health reduces healthy life expectancy and is thus an important problem for very elderly people. We investigated…”
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Vitamin D and periodontal disease by Amano, Yusuke, Komiyama, Kazuo, Makishima, Makoto

“…1,25-Dihydroxyvitamin D3 [1,25(OH)2D3; 1,25-dihydroxycholecalciferol or calcitriol] is the active form of vitamin D3, a lipid-soluble vitamin that plays a role…”
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Nickel ion inhibits nuclear factor-kappa B activity in human oral squamous cell carcinoma by Shionome, Takashi, Endo, Shigeki, Omagari, Daisuke, Asano, Masatake, Toyoma, Hitoshi, Ishigami, Tomohiko, Komiyama, Kazuo

“…The spontaneous IL-8 secretion observed in OSCC is partially dependent on the disregulated activity of transcription factor NF-κB. Nickel compounds are well…”
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Epiregulin is critical for the acinar cell regeneration of the submandibular gland in a mouse duct ligation model by Nagai, Koichi, Arai, Hideo, Okudera, Michisato, Yamamura, Takashi, Oki, Hidero, Komiyama, Kazuo

“…Acinar cell regeneration from tubular structures has been reported to occur in duct‐deligated salivary glands. However, the detailed process of acinar cell…”
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Estimation of trace metal elements in oral mucosa specimens by using SR-XRF, PIXE, and XAFS by Sugiyama, Tomoko, Uo, Motohiro, Wada, Takahiro, Omagari, Daisuke, Komiyama, Kazuo, Noguchi, Tadahide, Jinbu, Yoshinori, Kusama, Mikio

“…The effects of dissolved elements from metal dental restorations are a major concern in lesions of the oral mucosa, and the evaluation of accumulated metal…”
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Whole transcriptome analysis using next-generation sequencing of sterile-cultured Eisenia andrei for immune system research by Mikami, Yoshikazu, Fukushima, Atsushi, Kuwada-Kusunose, Takao, Sakurai, Tetsuya, Kitano, Taiichi, Komiyama, Yusuke, Iwase, Takashi, Komiyama, Kazuo

“…Recently, earthworms have become a useful model for research into the immune system, and it is expected that results obtained using this model will shed light…”
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Detection of trace metallic elements in oral lichenoid contact lesions using SR-XRF, PIXE and XAFS by Sugiyama, Tomoko, Uo, Motohiro, Wada, Takahiro, Omagari, Daisuke, Komiyama, Kazuo, Miyazaki, Serika, Numako, Chiya, Noguchi, Tadahide, Jinbu, Yoshinori, Kusama, Mikio, Mori, Yoshiyuki

“…Oral lichen planus (OLP) and oral lichenoid contact lesions (OLCL) are chronic inflammatory mucocutaneous reactions with a risk of malignant transformation…”
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Comparison of gene expression profiles of gingival carcinoma Ca9-22 cells and colorectal adenocarcinoma HT-29 cells to identify potentially important mediators of SLPI-induced cell migration by Takamura, Tsuyoshi, Suguro, Hisashi, Mikami, Yoshikazu, Iwase, Takashi, Komiyama, Yusuke, Kuyama, Kayo, Komiyama, Kazuo, Oki, Hiderou

“…Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor whose expression level is positively correlated with tumor aggressiveness and…”
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The Tokyo Oldest Old survey on Total Health (TOOTH): a longitudinal cohort study of multidimensional components of health and well-being by Arai, Yasumichi, Iinuma, Toshimitsu, Takayama, Michiyo, Takayama, Midori, Abe, Yukiko, Fukuda, Ryoko, Ando, Jyuko, Ohta, Kikuko, Hanabusa, Hiroo, Asakura, Keiko, Nishiwaki, Yuji, Gondo, Yasuyuki, Akiyama, Hiroko, Komiyama, Kazuo, Gionhaku, Nobuhito, Hirose, Nobuyoshi

“…With the rapid worldwide increase in the oldest old population, considerable concern has arisen about the social and economic burden of diseases and disability…”
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Current status of drug therapies for osteoporosis and the search for stem cells adapted for bone regenerative medicine by Mikami, Yoshikazu, Matsumoto, Taro, Kano, Koichiro, Toriumi, Taku, Somei, Masanori, Honda, Masaki J., Komiyama, Kazuo

“…A number of factors can lead to bone disorders such as osteoporosis, in which the balance of bone resorption vs. bone formation is upset (i.e., more bone is…”
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Alkaline phosphatase determines polyphosphate-induced mineralization in a cell-type independent manner by Mikami, Yoshikazu, Tsuda, Hiromasa, Akiyama, Yuko, Honda, Masaki, Shimizu, Noriyoshi, Suzuki, Naoto, Komiyama, Kazuo

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CD105 expression in oral capillary hemangiomas and cavernous hemangiomas by Matsumoto, Naoyuki, Tsuchiya, Motomi, Nomoto, Shouta, Matsue, Yasuyoshi, Nishikawa, Yohichi, Takamura, Tsuyoshi, Oki, Hidero, Komiyama, Kazuo

“…Capillary hemangioma (capillary lobular hemangioma) and cavernous hemangioma (venous malformation) are relatively common oral tumors/malformations and are…”
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