Search Results - "KOMIYAMA, Kanki"

Biologically Active Aspidofractinine, Rhazinilam, Akuammiline, and Vincorine Alkaloids from Kopsia by Subramaniam, G, Hiraku, Osamu, Hayashi, Masahiko, Koyano, Takashi, Komiyama, Kanki, Kam, Toh-Seok

“…Eleven new indole alkaloids, in addition to the previously reported rhazinal (1), and 14 other known alkaloids, were obtained from the Malayan Kopsia…”
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Bipleiophylline, an Unprecedented Cytotoxic Bisindole Alkaloid Constituted from the Bridging of Two Indole Moieties by an Aromatic Spacer Unit by Kam, Toh-Seok, Tan, Shin-Jowl, Ng, Seik-Weng, Komiyama, Kanki

“…A cytotoxic bisindole alkaloid possessing an unprecedented structure in which two indole moieties are bridged by an aromatic spacer unit has been isolated from…”
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Jerantinines A−G, Cytotoxic Aspidosperma Alkaloids from Tabernaemontana corymbosa by Lim, Kuan-Hon, Hiraku, Osamu, Komiyama, Kanki, Kam, Toh-Seok

“…Seven new indole alkaloids of the Aspidosperma type, jerantinines A−G (1−7), were isolated from a leaf extract of the Malayan Tabernaemontana corymbosa. The…”
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Biologically Active Indole Alkaloids from Kopsia arborea by Lim, Kuan-Hon, Hiraku, Osamu, Komiyama, Kanki, Koyano, Takashi, Hayashi, Masahiko, Kam, Toh-Seok

“…Nine new indole alkaloids, rhazinoline (1), 19(S)-methoxytubotaiwine (2), 19(R)-methoxytubotaiwine (3), kopsamidine A (4), kopsamidine B (5), kopsinidine A…”
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Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli by Ozawa, Masaaki, Kawamata, Shunsuke, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kishida, Akio, Kuroda, Chiaki, Ohsaki, Ayumi

“…Two new Erythrinan alkaloids, cristanines A and B (1, 2), were isolated from the bark of Erythrina crista-galli L. together with nine known Erythrinan…”
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Leuconicines A−G and (−)-Eburnamaline, Biologically Active Strychnan and Eburnan Alkaloids from Leuconotis by Gan, Chew-Yan, Low, Yun-Yee, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kam, Toh-Seok

“…Seven new indole alkaloids of the Strychnos type, leuconicines A−G (1−7), and a new eburnan alkaloid, (−)-eburnamaline (8), were isolated from the stem-bark…”
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Leucophyllidine, a Cytotoxic Bisindole Alkaloid Constituted From the Union of an Eburnan and a New Vinylquinoline Alkaloid by Gan, Chew-Yan, Robinson, Ward T, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kam, Toh-Seok

“…A cytotoxic bisindole alkaloid possessing an unprecedented structure constituted from the union of an eburnan half and a novel vinylquinoline alkaloid has been…”
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Macrodasines A–G, macroline indole alkaloids incorporating fused spirocyclic tetrahydrofuran–tetrahydrofuran and tetrahydrofuran–tetrahydropyran rings by Tan, Shin-Jowl, Robinson, Ward T., Komiyama, Kanki, Kam, Toh-Seok

“…The bark extract of the Malayan Alstonia angustifolia Wall provided the spirocyclic alkaloids macrodasines A–G. The structures of the new compounds were…”
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Inhibitory Effect of Erythraline on Toll-Like Receptor Signaling Pathway in RAW264.7 Cells by Etoh, Tadahiro, Kim, Yong Pil, Ohsaki, Ayumi, Komiyama, Kanki, Hayashi, Masahiko

“…Erythraline, isolated from the bark of Erythrina crista-galli which are used as Brazilian medicine plant for the treatment of inflammation diseases, suppressed…”
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New Constituents from the Leaves of Morinda citrifolia by Takashima, Junko, Ikeda, Yoshitaka, Komiyama, Kanki, Hayashi, Masahiko, Kishida, Akio, Ohsaki, Ayumi

“…A new iridoid glycoside, citrifoside (1), and a new anthraquinone, 1,5,15-trimethylmorindol (2), together with 24 known compounds, were isolated from the…”
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Leucoridines A−D, Cytotoxic Strychnos−Strychnos Bisindole Alkaloids from Leuconotis by Gan, Chew-Yan, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kam, Toh-Seok

“…Four new bisindole alkaloids of the Strychnos−Strychnos type, leucoridines A−D (1−4), were isolated from the stem-bark extract of Leuconotis griffithii…”
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Strychnan and Secoangustilobine A Type Alkaloids from Alstonia spatulata. Revision of the C-20 Configuration of Scholaricine by Tan, Shin-Jowl, Low, Yun-Yee, Choo, Yeun-Mun, Abdullah, Zanariah, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kam, Toh-Seok

“…A total of 25 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia spatulata, of which five are new alkaloids of the strychnan type…”
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TRAIL-enhancing activity of Erythrinan alkaloids from Erythrina velutina by Ozawa, Masaaki, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kishida, Akio, Ohsaki, Ayumi

“…A new Erythrinan alkaloid ( 1), erythodine N-oxide, was isolated from the seeds of Erythrina velutina together with seven known Erythrinan alkaloids ( 2– 7, 9)…”
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Biologically Active Aspidofractinine Alkaloids from Kopsia singapurensis by Subramaniam, G, Hiraku, Osamu, Hayashi, Masahiko, Koyano, Takashi, Komiyama, Kanki, Kam, Toh-Seok

“…Ten new indole alkaloids of the aspidofractinine type, in addition to several recently reported indole alkaloids and 20 other known alkaloids, were obtained…”
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Lundurines A–D, cytotoxic indole alkaloids incorporating a cyclopropyl moiety from Kopsia tenuis and revision of the structures of tenuisines A–C by Kam, Toh-Seok, Lim, Kuan-Hon, Yoganathan, K., Hayashi, Masahiko, Komiyama, Kanki

“…The leaf extract of the Borneo Kopsia, K. tenuis, provided several new indoles with a novel hexacyclic carbon skeleton, incorporating a cyclopropyl moiety. Two…”
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Structure, biological activity, and a biomimetic partial synthesis of the lirofolines, novel pentacylic indole alkaloids from Tabernaemontana by Low, Yun-Yee, Lim, Kuan-Hon, Choo, Yeun-Mun, Pang, Huey-Shen, Etoh, Tadahiro, Hayashi, Masahiko, Komiyama, Kanki, Kam, Toh-Seok

“…Two new pentacyclic indole alkaloids, lirofolines A and B, possessing a novel rearranged ibogan ring system, are obtained from two Malayan Tabernaemontana…”
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The alkaloids of the mersinine group: a new subclass of the monoterpenoid indole alkaloids from Kopsia by Subramaniam, G., Choo, Yeun-Mun, Hiraku, Osamu, Komiyama, Kanki, Kam, Toh-Seok

“…A total of 16 alkaloids, exemplified by mersinine A and its congeners, and constituting a new subclass of the monoterpenoid indoles, were isolated exclusively…”
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Isolation of Ursolic Acid from Apple Peels and Its Specific Efficacy as a Potent Antitumor Agent by Yamaguchi, Hideaki, Noshita, Toshiro, Kidachi, Yumi, Umetsu, Hironori, Hayashi, Masahiko, Komiyama, Kanki, Funayama, Shinji, Ryoyama, Kazuo

“…Dried apple peels were extracted with n-hexane, chloroform, and methanol successively. The portion of the chloroform extract that showed the strongest…”
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Suppression of Bone Resorption by Madindoline A, a Novel Nonpeptide Antagonist to gp130 by Hayashi, Masahiko, Rho, Mun-Chual, Enomoto, Akiko, Fukami, Akiko, Kim, Yong-Pil, Kikuchi, Yuji, Sunazuka, Toshiaki, Hirose, Tomoyasu, Komiyama, Kanki, Omura, Satoshi

“…IL-6 is a multifunctional cytokine involved in regulation of differentiation, antibody production, and growth of certain types of tumor cells. Its excessive…”
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Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations by Sunazuka, Toshiaki, Hirose, Tomoyasu, Shirahata, Tatsuya, Harigaya, Yoshihiro, Hayashi, Masahiko, Komiyama, Kanki, Ōmura, Satoshi, Smith, Amos B

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