Search Results - "KOMIYA, SETSURO"

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury by Abematsu, Masahiko, Tsujimura, Keita, Yamano, Mariko, Saito, Michiko, Kohno, Kenji, Kohyama, Jun, Namihira, Masakazu, Komiya, Setsuro, Nakashima, Kinichi

“…The body's capacity to restore damaged neural networks in the injured CNS is severely limited. Although various treatment regimens can partially alleviate…”
Get full text

Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human Induced Pluripotent Stem Cell-Derived Long-Term Self-Renewing Neuroepithelial-Like Stem Cells by Fujimoto, Yusuke, Abematsu, Masahiko, Falk, Anna, Tsujimura, Keita, Sanosaka, Tsukasa, Juliandi, Berry, Semi, Katsunori, Namihira, Masakazu, Komiya, Setsuro, Smith, Austin, Nakashima, Kinichi

“…Because of their ability to self‐renew, to differentiate into multiple lineages, and to migrate toward a damaged site, neural stem cells (NSCs), which can be…”
Get full text

Risk factors for surgical site infection and urinary tract infection after spine surgery by Tominaga, Hiroyuki, Setoguchi, Takao, Ishidou, Yasuhiro, Nagano, Satoshi, Yamamoto, Takuya, Komiya, Setsuro

“…Purpose This study aimed to identify and compare risk factors for surgical site infection (SSI) and non-surgical site infections (non-SSIs), particularly…”
Get full text

Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury by Nakajo, Masahide, Uezono, Naohiro, Nakashima, Hideyuki, Wake, Hidenori, Komiya, Setsuro, Nishibori, Masahiro, Nakashima, Kinichi

“…•Administration of anti-HMGB1 mAb within 6 h after SCI improves functional recovery.•Anti-HMGB1 mAb protects the BSCB.•Anti-HMGB1 mAb suppresses inflammation…”
Get full text

BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts by Yahiro, Yuhei, Maeda, Shingo, Morikawa, Masato, Koinuma, Daizo, Jokoji, Go, Ijuin, Toshiro, Komiya, Setsuro, Kageyama, Ryoichiro, Miyazono, Kohei, Taniguchi, Noboru

“…Adult bone structural integrity is maintained by remodeling via the coupling of osteoclastic bone resorption and osteoblastic bone formation. Osteocytes or…”
Get full text

Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma by Bureta, Costansia, Saitoh, Yoshinobu, Tokumoto, Hiroto, Sasaki, Hiromi, Maeda, Shingo, Nagano, Satoshi, Komiya, Setsuro, Taniguchi, Noboru, Setoguchi, Takao

“…The treatment of glioblastoma is a critical health issue, owing to its resistance to chemotherapy. The current standard of treatment is surgical resection,…”
Get full text

Validation of Different Nutritional Assessment Tools in Predicting Prognosis of Patients with Soft Tissue Spindle-Cell Sarcomas by Sasaki, Hiromi, Nagano, Satoshi, Komiya, Setsuro, Taniguchi, Noboru, Setoguchi, Takao

“…Predicting outcomes in patients with soft tissue sarcoma (STS) is challenging. To improve these predictions, we retrospectively analyzed common nutritional…”
Get full text

Differentiation of lipoma and atypical lipomatous tumor by a scoring system: implication of increased vascularity on pathogenesis of liposarcoma by Nagano, Satoshi, Yokouchi, Masahiro, Setoguchi, Takao, Ishidou, Yasuhiro, Sasaki, Hiromi, Shimada, Hirofumi, Komiya, Setsuro

“…Well-differentiated liposarcoma (WDL)/atypical lipomatous tumor (ALT) is considered a low-grade malignancy that rarely metastasizes but should be carefully…”
Get full text

Current therapeutic modalities and newly designed gene therapy for refractory sarcomas by Komiya, Setsuro, Nagano, Satoshi, Setoguchi, Takao

Get full text

Smoothened as a new therapeutic target for human osteosarcoma by Hirotsu, Masataka, Setoguchi, Takao, Sasaki, Hiromi, Matsunoshita, Yukihiro, Gao, Hui, Nagao, Hiroko, Kunigou, Osamu, Komiya, Setsuro

“…The Hedgehog signaling pathway functions as an organizer in embryonic development. Recent studies have demonstrated constitutive activation of Hedgehog pathway…”
Get full text

Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis by Taniguchi, Noboru, Caramés, Beatriz, Ronfani, Lorenza, Ulmer, Ulrich, Komiya, Setsuro, Bianchi, Marco E, Lotz, Martin

“…Osteoarthritis (OA) is the most common joint disease and typically begins with an aging-related disruption of the articular cartilage surface. Mechanisms…”
Get full text

Clinical outcomes of arthroscopic rotator cuff repair: a retrospective comparison of double-layer, double-row and suture bridge methods by Kakoi, Hironori, Izumi, Toshihiko, Fujii, Yasunari, Nagano, Satoshi, Setoguchi, Takao, Ishidou, Yasuhiro, Komiya, Setsuro

“…The suture-bridge (SB) method has recently become the mainstream means of repairing full-thickness rotator cuff tears. However, in some patients the deep and…”
Get full text

The diagnostic value of single-photon emission computed tomography/computed tomography for severe sacroiliac joint dysfunction by Tofuku, Katsuhiro, Koga, Hiroaki, Komiya, Setsuro

“…Purpose We aimed to evaluate the value of single-photon emission computed tomography (SPECT)/computed tomography (CT) for the diagnosis of sacroiliac joint…”
Get full text

Tranilast enhances the effect of anticancer agents in osteosarcoma by Nakashima, Takayuki, Nagano, Satoshi, Setoguchi, Takao, Sasaki, Hiromi, Saitoh, Yoshinobu, Maeda, Shingo, Komiya, Setsuro, Taniguchi, Noboru

“…Tranilast [N‑(3',4'‑dimethoxycinnamoyl)‑anthranilic acid], initially developed as an antiallergic drug, also exhibits a growth inhibitory effect on various…”
Get full text

The effect of ultraviolet photofunctionalization of titanium instrumentation in lumbar fusion: a non-randomized controlled trial by Tominaga, Hiroyuki, Matsuyama, Kanehiro, Morimoto, Yukihiro, Yamamoto, Takuya, Komiya, Setsuro, Ishidou, Yasuhiro

“…Titanium instrumentations are widely used in orthopedics; the metal bonds with bone in a process called osseointegration. Over time, hydrocarbons adhere to the…”
Get full text

Clinical course of the bony lesion of single-system single-site Langerhans cell histiocytosis – Is appropriate follow-up sufficient treatment? by Sasaki, Hiromi, Nagano, Satoshi, Shimada, Hirofumi, Nakamura, Shunsuke, Setoguchi, Takao, Komiya, Setsuro

“…Langerhans cell histiocytosis (LCH) is categorized into three types, which include single-system single-site (SS-s), single-system multiple-site (SS-m) and…”
Get full text

Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion by Nagao-Kitamoto, Hiroko, Setoguchi, Takao, Kitamoto, Sho, Nakamura, Shunsuke, Tsuru, Arisa, Nagata, Masahito, Nagano, Satoshi, Ishidou, Yasuhiro, Yokouchi, Masahiro, Kitajima, Shinichi, Yoshioka, Takako, Maeda, Shingo, Yonezawa, Suguru, Komiya, Setsuro

“…Highlights • RPS3 was identified as a novel downstream gene of GLI2. • Knockdown of GLI2 decreased RPS3 expression in osteosarcoma cells. • RPS3 knockdown…”
Get full text

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: Functional analysis of p62 and autophagy in hypoxic neuronal cells by Tanabe, Fumito, Yone, Kazunori, Kawabata, Naoya, Sakakima, Harutoshi, Matsuda, Fumiyo, Ishidou, Yasuhiro, Maeda, Shingo, Abematsu, Masahiko, Komiya, Setsuro, Setoguchi, Takao

“…Intracellular accumulation of altered proteins, including p62 and ubiquitinated proteins, is the basis of most neurodegenerative disorders. The relationship…”
Get full text

Association between bone mineral density, muscle volume, walking ability, and geriatric nutritional risk index in hemodialysis patients by Tominaga, Hiroyuki, Oku, Manei, Arishima, Yoshiya, Ikeda, Toru, Ishidou, Yasuhiro, Nagano, Satoshi, Minami, Masato, Ido, Akio, Komiya, Setsuro, Setoguchi, Takao

“…Background and Objectives: Hemodialysis patients are at risk for bone loss and sarcopenia, characterized by reduced muscle mass and limited mobility/function…”
Get full text

Predictive factors of mortality and deterioration in performance of activities of daily living after hip fracture surgery in Kagoshima, Japan by Ishidou, Yasuhiro, Koriyama, Chihaya, Kakoi, Hironori, Setoguchi, Takao, Nagano, Satoshi, Hirotsu, Masataka, Yamamoto, Takuya, Yokouchi, Masahiro, Komiya, Setsuro

“…Aim Given that different hospitals achieve different outcomes, optimal evaluation of treatment outcomes in the local community requires evaluation of many…”
Get full text