Search Results - "KOLLURI, Siva Kumar"

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target by Kolluri, Siva Kumar, Jin, Un-Ho, Safe, Stephen

“…The aryl hydrocarbon receptor (AhR) was initially identified as the receptor that binds and mediates the toxic effects induced by 2,3,7,8-tetrachlorodibenzo- p…”
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Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer by Ye, Qing, Mohamed, Rehab, Dakhlallah, Duaa, Gencheva, Marieta, Hu, Gangqing, Pearce, Martin C, Kolluri, Siva Kumar, Marsh, Clay B, Eubank, Timothy D, Ivanov, Alexey V, Guo, Nancy Lan

“…Our previous study found that zinc finger protein 71 (ZNF71) mRNA expression was associated with chemosensitivity and its protein expression was prognostic of…”
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Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands by Bisson, William H., Koch, Daniel C., O’Donnell, Edmond F., Khalil, Sammy M., Kerkvliet, Nancy I., Tanguay, Robert L., Abagyan, Ruben, Kolluri, Siva Kumar

“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor; the AhR Per-AhR/Arnt-Sim (PAS) domain binds ligands. We developed homology…”
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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor by O'Donnell, Edmond F, Saili, Katerine S, Koch, Daniel C, Kopparapu, Prasad R, Farrer, David, Bisson, William H, Mathew, Lijoy K, Sengupta, Sumitra, Kerkvliet, Nancy I, Tanguay, Robert L, Kolluri, Siva Kumar

“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related…”
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The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells by O'Donnell, Edmond F, Kopparapu, Prasad Rao, Koch, Daniel C, Jang, Hyo Sang, Phillips, Jessica Lynne, Tanguay, Robert L, Kerkvliet, Nancy I, Kolluri, Siva Kumar

“…A novel role of the dihydroorotatedehydrogenase (DHODH) inhibitor leflunomide as a potential anti-melanoma therapy was recently reported (Nature 471:518-22,…”
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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease by Punj, Sumit, Kopparapu, Prasad, Jang, Hyo Sang, Phillips, Jessica L, Pennington, Jamie, Rohlman, Diana, O'Donnell, Edmond, Iversen, Patrick L, Kolluri, Siva Kumar, Kerkvliet, Nancy I

“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses…”
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Retinoid X Receptor Regulates Nur77/Thyroid Hormone Receptor 3-Dependent Apoptosis by Modulating Its Nuclear Export and Mitochondrial Targeting by Cao, Xihua, Liu, Wen, Lin, Feng, Li, Hui, Kolluri, Siva Kumar, Lin, Bingzhen, Han, Young-hoon, Dawson, Marcia I., Zhang, Xiao-kun

“…ERRATUM ( vol. 25 , p. 524 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells by Kolluri, Siva Kumar, Bruey-Sedano, Nathalie, Cao, Xihua, Lin, Bingzhen, Lin, Feng, Han, Young-Hoon, Dawson, Marcia I., Zhang, Xiao-kun

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Cytochrome c Release and Apoptosis Induced by Mitochondrial Targeting of Nuclear Orphan Receptor TR3 by Li, Hui, Kolluri, Siva Kumar, Gu, Jian, Dawson, Marcia I., Cao, Xihua, Hobbs, Peter D., Lin, Bingzhen, Chen, Guo-quen, Lu, Jiang-song, Lin, Feng, Xie, Zhihua, Fontana, Joseph A., Reed, John C., Zhang, Xiao-kun

“…TR3, an immediate-early response gene and an orphan member of the steroid-thyroid hormone-retinoid receptor superfamily of transcription factors, regulates…”
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Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma by Luciano, Frederic, Krajewska, Maryla, Ortiz-Rubio, Paulina, Krajewski, Stan, Zhai, Dayong, Faustin, Benjamin, Bruey, Jean-Marie, Bailly-Maitre, Beatrice, Lichtenstein, Alan, Kolluri, Siva Kumar, Satterthwait, Arnold C., Zhang, Xiao-Kun, Reed, John C.

“…Defects in apoptosis mechanisms play important roles in malignancy and autoimmunity. Orphan nuclear receptor Nur77/TR3 has been demonstrated to bind…”
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Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells by Jang, Hyo Sang, Pearce, Martin, O'Donnell, Edmond F, Nguyen, Bach Duc, Truong, Lisa, Mueller, Monica J, Bisson, William H, Kerkvliet, Nancy I, Tanguay, Robert L, Kolluri, Siva Kumar

“…We previously reported that raloxifene, an estrogen receptor modulator, is also a ligand for the aryl hydrocarbon receptor (AhR). Raloxifene induces apoptosis…”
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The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis by Kolluri, Siva Kumar, Corr, Maripat, James, Sharon Y., Bernasconi, Michele, Lu, Desheng, Liu, Wen, Cottam, Howard B., Leoni, Lorenzo M., Carson, Dennis A., Zhang, Xiao-kun

“…Prostate cancer is often slowly progressive, and it can be difficult to treat with conventional cytotoxic drugs. Nonsteroidal antiinflammatory drugs inhibit…”
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Regulation of retinoic acid receptor β expression by peroxisome proliferator-activated receptor γ ligands in cancer cells by JAMES, Sharon Y, FENG LIN, SIVA KUMAR KOLLURI, DAWSON, Marcia I, ZHANG, Xiao-Kun

“…The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor family member that can form a heterodimeric complex with retinoid X…”
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Unique anti-activator protein-1 activity of retinoic acid receptor β by FENG LIN, DONGMEI XIAO, SIVA KUMAR KOLLURI, ZHANG, X.-K

“…The anticancer effects of retinoids are mainly mediated by two classes of nuclear receptors, the retinoic acid receptors (RARs) and retinoid X receptors…”
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Complementation of Ah Receptor Deficiency in Hepatoma Cells: Negative Feedback Regulation and Cell Cycle Control by the Ah Receptor by Weiß, Carsten, Kolluri, Siva Kumar, Kiefer, Franz, Göttlicher, Martin

“…The Ah receptor (AhR) is a ligand-dependent transcription factor subunit that heterodimerizes with the AhR nuclear translocator (Arnt) and mediates the…”
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Orphan Receptor COUP-TF Is Required for Induction of Retinoic Acid Receptor β, Growth Inhibition, and Apoptosis by Retinoic Acid in Cancer Cells by Lin, Bingzhen, Chen, Guo-quan, Xiao, Dongmei, Kolluri, Siva Kumar, Cao, Xihua, Su, Hong, Zhang, Xiao-kun

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Novel target genes of the Ah (dioxin) receptor: Transcriptional induction of N-myristoyltransferase 2 by SIVA KUMAR KOLLURI, BALDUF, Carolin, HOFMANN, Martin, GÖTTLICHER, Martin

“…Dioxins are potent mammalian carcinogens and toxins affecting liver, skin, and immune and reproductive systems. The intracellular Ah receptor, a…”
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Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity by DAWSON, Marcia I, HOBBS, Peter D, ZHANG, Xiao-Kun, YUXIANG ZHANG, FONTANA, Joseph A, PETERSON, Valerie J, LEID, Mark, LANGE, Christopher W, FENG, Kai-Chia, CHEN, Guo-Quan, JIAN GU, HUI LI, SIVA KUMAR KOLLURI

“…The retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) is reported to have anticancer activity in vivo. Induction of cell cycle…”
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Regulation of Retinoic Acid-induced Inhibition of AP-1 Activity by Orphan Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor by Lin, Feng, Kolluri, Siva Kumar, Chen, Guo-quan, Zhang, Xiao-kun

“…Retinoids are therapeutically effective in the treatment of various cancers, and some of the therapeutic action of retinoids can be ascribed to their potent…”
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Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects by O’Donnell, Edmond Francis, Jang, Hyo Sang, Liefwalker, Daniel F, Kerkvliet, Nancy I, Kolluri, Siva Kumar

“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic Helix-Loop-Helix/Per-Arnt-Sim) family of…”
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