Search Results - "KOKKOTIS, GEORGIOS"
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Co-expression of fibrotic genes in inflammatory bowel disease; A localized event?
Published in Frontiers in immunology (23-12-2022)“…Extracellular matrix turnover, a ubiquitous dynamic biological process, can be diverted to fibrosis. The latter can affect the intestine as a serious…”
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Predictors of Response to Vedolizumab in Patients with Ulcerative Colitis: Results from the Greek VEDO-IBD Cohort
Published in Digestive diseases and sciences (01-03-2022)“…Background Optimization of treatment with biologics is currently an unmet need for patients with ulcerative colitis (UC). Real-world studies provide neutral…”
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Letter: COVID‐19 outcomes and anti‐TNF treatments—comprehensive evidence matters. Authors' reply
Published in Alimentary pharmacology & therapeutics (01-05-2022)“…LINKED CONTENT This article is linked to Kokkotis et al papers. To view these articles, visit https://doi.org/10.1111/apt.16717 and…”
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Targeting the Sphingosine-1-Phosphate Pathway: New Opportunities in Inflammatory Bowel Disease Management
Published in Drugs (New York, N.Y.) (01-10-2024)“…Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC) are chronic immune-mediated diseases which primarily target the…”
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Systematic review with meta‐analysis: COVID‐19 outcomes in patients receiving anti‐TNF treatments
Published in Alimentary pharmacology & therapeutics (01-01-2022)“…Summary Background Accumulating evidence suggests a beneficial effective of tumour necrosis factor‐alpha (TNF‐α) inhibitors on the outcomes of COVID‐19…”
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The IBD-F Patient Self-Assessment Scale Accurately Depicts the Level of Fatigue and Predicts a Negative Effect on the Quality of Life of Patients With IBD in Clinical Remission
Published in Inflammatory bowel diseases (17-05-2021)“…Abstract Background Fatigue is highly prevalent among patients with inflammatory bowel disease (IBD) and may have an unfavorable impact on quality of life…”
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Oncostatin M Induces a Pro-inflammatory Phenotype in Intestinal Subepithelial Myofibroblasts
Published in Inflammatory bowel diseases (04-11-2024)“…Abstract Background Oncostatin-M (OSM) is associated with antitumor necrosis factor (anti-TNF)-α resistance in inflammatory bowel disease (IBD) and fibrosis in…”
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Prevalence and predictors of arthralgia after initiation of vedolizumab in patients with inflammatory bowel disease: a retrospective cohort study
Published in European journal of gastroenterology & hepatology (01-04-2023)“…Vedolizumab is a mAb used for the treatment of moderate to severe ulcerative colitis and Crohn's disease. There is evidence that administration of vedolizumab…”
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Response to Anti-α4β7 Blockade in Patients With Ulcerative Colitis Is Associated With Distinct Mucosal Gene Expression Profiles at Baseline
Published in Inflammatory bowel diseases (05-01-2022)“…Abstract Background Improving treatment outcomes with biological therapy is a demanding current need for patients with inflammatory bowel disease. Discovery of…”
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The Burden of COVID-19 in Adult Patients With Hematological Malignancies: A Single-center Experience After the Implementation of Mass-vaccination Programs Against SARS-CoV-2
Published in In vivo (Athens) (01-11-2023)“…BACKGROUND/AIMDespite the widespread mass-vaccination programs worldwide and the continuing evolution of COVID-19 therapeutics, the burden of SARS-CoV-2…”
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Patients With Inflammatory Bowel Diseases Have Impaired Antibody Production After Anti-SARS-CoV-2 Vaccination: Results From a Panhellenic Registry
Published in Inflammatory bowel diseases (01-02-2023)“…Abstract Background Four EMA-approved vaccines against SARS-CoV-2 are currently available. Data regarding antibody responses to initial vaccination regimens in…”
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Pregnancy outcomes in Greek women with inflammatory bowel disease: a longitudinal national retrospective study
Published in European journal of gastroenterology & hepatology (23-09-2024)“…Inflammatory bowel disease (IBD) commonly affects patients of reproductive age. The effect of disease activity on the outcome of pregnancy and its impact on…”
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Prolonged SARS -CoV-2 Infection With Common Features in Two Patients Receiving Anti-CD20 Therapy
Published in In vivo (Athens) (01-01-2023)“…Anti-CD20-depleting monoclonal antibodies predispose patients to the development of severe disease of SARS-CoV-2 infection. These antibodies are given as…”
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The natural history of COVID-19 in patients with inflammatory bowel disease: a nationwide study by the Hellenic Society for the study of IBD
Published in European journal of gastroenterology & hepatology (01-12-2021)“…COVID-19 has evolved into a global health crisis, variably affecting the management of patients with chronic illnesses. Patients with inflammatory bowel…”
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The burden and management of anemia in Greek patients with inflammatory bowel disease: a retrospective, multicenter, observational study
Published in BMC gastroenterology (29-06-2021)“…Background Anemia is a common extraintestinal manifestation of Inflammatory Bowel Disease (IBD) affecting negatively the patients' quality of life. The aim of…”
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The Inflammatory Bowel Disease-Disk Tool for Assessing Disability in Inflammatory Bowel Disease Patients: Validation of the Greek Version
Published in Journal of clinical medicine (21-04-2023)“…The Inflammatory Bowel Disease-Disk (IBD-Disk) is a physician-administered tool that evaluates the functional status of patients with Inflammatory Bowel…”
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