Search Results - "KOJIMA, Hiroshi"

Comparison of the Effect of Ranibizumab and Verteporfin for Polypoidal Choroidal Vasculopathy: 12-Month LAPTOP Study Results by Oishi, Akio, Kojima, Hiroshi, Mandai, Michiko, Honda, Shigeru, Matsuoka, Toshiyuki, Oh, Hideyasu, Kita, Mihori, Nagai, Tomoko, Fujihara, Masashi, Bessho, Nobuhiro, Uenishi, Mamoru, Kurimoto, Yasuo, Negi, Akira

“…Purpose To compare the effect of photodynamic therapy (PDT) and intravitreal ranibizumab in patients with polypoidal choroidal vasculopathy (PCV). Design…”
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Lung cancer detection in perioperative patients' exhaled breath with nanomechanical sensor array by Saeki, Yusuke, Maki, Naoki, Nemoto, Takahiro, Inada, Katsushige, Minami, Kosuke, Tamura, Ryo, Imamura, Gaku, Cho-Isoda, Yukiko, Kitazawa, Shinsuke, Kojima, Hiroshi, Yoshikawa, Genki, Sato, Yukio

“…[Display omitted] •Early lung cancer detection is vital due to its high mortality in advanced stage.•We created a novel membrane-type surface stress sensor for…”
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Increased Soluble CD155 in the Serum of Cancer Patients by Iguchi-Manaka, Akiko, Okumura, Genki, Kojima, Hiroshi, Cho, Yukiko, Hirochika, Rei, Bando, Hiroko, Sato, Toyomi, Yoshikawa, Hiroyuki, Hara, Hisato, Shibuya, Akira, Shibuya, Kazuko

“…Emerging evidence suggests that DNAM-1 (CD226) play an important role in the recognition of tumor cells and their lysis by cytotoxic T lymphocytes (CTL) and NK…”
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Statistical Evaluation of Total Expiratory Breath Samples Collected throughout a Year: Reproducibility and Applicability toward Olfactory Sensor-Based Breath Diagnostics by Inada, Katsushige, Kojima, Hiroshi, Cho-Isoda, Yukiko, Tamura, Ryo, Imamura, Gaku, Minami, Kosuke, Nemoto, Takahiro, Yoshikawa, Genki

“…The endogenous volatile organic compounds (VOCs) in exhaled breath can be promising biomarkers for various diseases including cancers. An olfactory sensor has…”
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Multi-institutional prospective feasibility study to explore tolerability and efficacy of oral nutritional supplements for patients with gastric cancer undergoing gastrectomy (CCOG1301) by Kobayashi, Daisuke, Ishigure, Kiyoshi, Mochizuki, Yoshinari, Nakayama, Hiroshi, Sakai, Mitsuru, Ito, Seiji, Kojima, Hiroshi, Kajikawa, Masaki, Ando, Masahiko, Kodera, Yasuhiro

“…Background Postoperative malnutrition after gastrectomy is deemed inevitable, which could have prejudicial influence on survival for gastric cancer patients. A…”
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PPARγ Agonists Attenuate Palmitate-Induced ER Stress through Up-Regulation of SCD-1 in Macrophages by Ikeda, Jiro, Ichiki, Toshihiro, Takahara, Yusuke, Kojima, Hiroshi, Sankoda, Chikahiro, Kitamoto, Shiro, Tokunou, Tomotake, Sunagawa, Kenji

“…Clinical trials have shown that treatment of patients with type 2 diabetes with pioglitazone, a peroxisome proliferator-activated receptor (PPAR)γ agonist,…”
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Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study by Oki, Eiji, Emi, Yasunori, Kojima, Hiroshi, Higashijima, Jun, Kato, Takeshi, Miyake, Yasuhiro, Kon, Masanori, Ogata, Yutaka, Takahashi, Kenichi, Ishida, Hideyuki, Saeki, Hiroshi, Sakaguchi, Yoshihisa, Yamanaka, Takeharu, Kono, Toru, Tomita, Naohiro, Baba, Hideo, Shirabe, Ken, Kakeji, Yoshihiro, Maehara, Yoshihiko

“…Background Peripheral sensory neurotoxicity is a frequent adverse effect of oxaliplatin therapy. Calcium and magnesium (Ca/Mg) infusions are frequently used as…”
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Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa by Guo, Congrong, Otani, Atsushi, Oishi, Akio, Kojima, Hiroshi, Makiyama, Yukiko, Nakagawa, Satoko, Yoshimura, Nagahisa

“…Neuroinflammation involving CC chemokines such as monocyte chemoattractant protein-1 (MCP-1) has been demonstrated in the pathological process of retinitis…”
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Oral Antibiotics are Effective for Preventing Colonoscopy-associated Peritonitis as a Preemptive Therapy in Patients on Peritoneal Dialysis by Suzuki, Yasuhiro, Mizuno, Masashi, Kojima, Hiroshi, Sato, Yuka, Kim, Hangsoo, Kinashi, Hiroshi, Katsuno, Takayuki, Ishimoto, Takuji, Maruyama, Shoichi, Ito, Yasuhiko

“…Objective In patients on peritoneal dialysis (PD), it was reported that colonoscopy, but not upper gastrointestinal endoscopy, could cause peritonitis as a…”
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Refractory Hypotension Caused by Selenium Deficiency in a Patient on Peritoneal Dialysis by Ryuge, Akihiro, Kim, Hangsoo, Suzuki, Yasuhiro, Okazaki, Masaki, Kojima, Hiroshi, Saito, Shoji, Kato, Noritoshi, Ishimoto, Takuji, Kosugi, Tomoki, Maruyama, Shoichi, Mizuno, Masashi

“…Selenium is essential for human health; its deficiency leads to cardiac dysfunction. We herein report a 79-year-old man on peritoneal dialysis who presented…”
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Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial by Tsuburaya, Akira, MD, Yoshida, Kazuhiro, Dr, Kobayashi, Michiya, MD, Yoshino, Shigefumi, MD, Takahashi, Masazumi, MD, Takiguchi, Nobuhiro, MD, Tanabe, Kazuaki, MD, Takahashi, Naoto, MD, Imamura, Hiroshi, MD, Tatsumoto, Naokuni, MD, Hara, Akinori, MD, Nishikawa, Kazuhiro, MD, Fukushima, Ryoji, MD, Nozaki, Isao, MD, Kojima, Hiroshi, MD, Miyashita, Yumi, RN, Oba, Koji, PhD, Buyse, Marc, ScD, Morita, Satoshi, PhD, Sakamoto, Junichi, MD

“…Summary Background The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant…”
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Peritoneal Expression of Membrane Complement Regulators Is Decreased in Peritoneal Dialysis Patients with Infected Peritonitis by Fukui, Sosuke, Mizuno, Masashi, Tawada, Mitsuhiro, Suzuki, Yasuhiro, Kojima, Hiroshi, Matsukawa, Yoshihisa, Imai, Masaki, Kim, Hangsoo, Kinashi, Hiroshi, Mizutani, Makoto, Minoshima, Kenichi, Maruyama, Shoichi, Ito, Yasuhiko

“…In peritoneal dialysis (PD) patients, fungi and are considered important causative microorganisms for peritonitis with poor prognosis. Our objective was to…”
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Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy by Kono, Toru, Hata, Taishi, Morita, Satoshi, Munemoto, Yoshinori, Matsui, Takanori, Kojima, Hiroshi, Takemoto, Hiroyoshi, Fukunaga, Mutsumi, Nagata, Naoki, Shimada, Mitsuo, Sakamoto, Junichi, Mishima, Hideyuki

“…Purpose Oxaliplatin-induced peripheral neurotoxicity (OPN) is frequent and potentially severe, but successful treatment of this condition is still an unmet…”
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Higher dental care is positively associated with key prognosis factors in peritoneal dialysis patients: findings from a retrospective study by Hiramatsu, Takeyuki, Okumura, Shota, Iguchi, Daiki, Kojima, Hiroshi

“…Abstract Background Oral disease may be increased in people with end-stage renal disease and associated with inflammation, cardiovascular disease, and…”
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Serum affects keratinization and tight junctions in three-dimensional cultures of the mouse keratinocyte cell line COCA through retinoic acid receptor-mediated signaling by Ozaki, Akane, Otani, Takahito, Kitagawa, Norio, Ogata, Kayoko, Iida, Hiroshi, Kojima, Hiroshi, Inai, Tetsuichiro

“…Vitamin A, which is found in serum, is known to affect keratinocyte proliferation, epidermal differentiation, and keratinization. In mice, stratified epithelia…”
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Serum and plasma levels of Ba, but not those of soluble C5b-9, might be affected by renal function in chronic kidney disease patients by Yamane, Ryoko, Yasuda, Yoshinari, Oshima, Aki, Suzuki, Yasuhiro, Kojima, Hiroshi, Kim, Hangsoo, Fukui, Sosuke, Maruyama, Shoichi, Ito, Yasuhiko, Mizuno, Masashi

“…During the last few decades, pathogenic mechanisms associated with uncontrolled activation of the complement (C) system and development of anti-C agents have…”
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TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility by Sekiya, Takeshi, Ogura, Yukino, Kai, Hirayasu, Kawaguchi, Atsushi, Okawa, Shino, Hirohama, Mikako, Kuroki, Takahiro, Morii, Wataru, Hara, Akira, Hiramatsu, Yuji, Hitomi, Shigemi, Kawakami, Yasushi, Arakawa, Yoshihiro, Maruo, Kazushi, Chiba, Shigeru, Suzuki, Hiromichi, Kojima, Hiroshi, Tachikawa, Hirokazu, Yamagata, Kunihiro

“…COVID-19 has a wide range of clinical presentations, and the susceptibility to SARS-CoV-2 infection and the mortality rate also vary by region and ethnicity…”
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Prognostic and predictive value of extended RAS mutation and mismatch repair status in stage III colorectal cancer by Sasaki, Yusuke, Akasu, Takayuki, Saito, Norio, Kojima, Hiroshi, Matsuda, Keiji, Nakamori, Shoji, Komori, Koji, Amagai, Kenji, Yamaguchi, Tatsuro, Ohue, Masayuki, Nagashima, Kengo, Yamada, Yasuhide

“…The prognostic and predictive value of KRAS gene mutations in stage III colorectal cancer is controversial because many recent clinical trials have not…”
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Morphological study of tooth development in podoplanin-deficient mice by Takara, Kenyo, Maruo, Naoki, Oka, Kyoko, Kaji, Chiaki, Hatakeyama, Yuji, Sawa, Naruhiko, Kato, Yukinari, Yamashita, Junro, Kojima, Hiroshi, Sawa, Yoshihiko

“…Podoplanin is a mucin-type highly O-glycosylated glycoprotein identified in several somatyic cells: podocytes, alveolar epithelial cells, lymphatic endothelial…”
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Plasma concentrations of dasatinib have a clinical impact on the frequency of dasatinib dose reduction and interruption in chronic myeloid leukemia: an analysis of the DARIA 01 study by Mizuta, Shuichi, Sawa, Masashi, Tsurumi, Hisashi, Matsumoto, Kana, Miyao, Kotaro, Hara, Takeshi, Takahashi, Takeshi, Sakemura, Reona, Kojima, Hiroshi, Kohno, Akio, Oba, Mari S., Morita, Satoshi, Sakamoto, Junichi, Emi, Nobuhiko

“…Background Dasatinib has shown promising anti-leukemic activity against chronic myeloid leukemia (CML). However, patients receiving dasatinib frequently…”
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