Search Results - "KOIZUMI, JUNJI"

Genotypic and phenotypic features in homozygous familial hypercholesterolemia caused by proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) gain-of-function mutation by Mabuchi, Hiroshi, Nohara, Atsushi, Noguchi, Tohru, Kobayashi, Junji, Kawashiri, Masa-aki, Inoue, Takeshi, Mori, Mika, Tada, Hayato, Nakanishi, Chiaki, Yagi, Kunimasa, Yamagishi, Masakazu, Ueda, Kousei, Takegoshi, Tadayoshi, Miyamoto, Susumu, Inazu, Akihiro, Koizumi, Junji

“…Abstract Backgrounds Familial hypercholesterolemia (FH) is an autosomal dominant disease characterized by hypercholesterolemia, tendon xanthomas, and premature…”
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Development of quality indicators for care of chronic kidney disease in the primary care setting using electronic health data: a RAND-modified Delphi method by Fukuma, Shingo, Shimizu, Sayaka, Niihata, Kakuya, Sada, Ken-ei, Yanagita, Motoko, Hatta, Tsuguru, Nangaku, Masaomi, Katafuchi, Ritsuko, Fujita, Yoshiro, Koizumi, Junji, Koizumi, Shunzo, Kimura, Kenjiro, Fukuhara, Shunichi, Shibagaki, Yugo

“…Background The prevalence of chronic kidney disease (CKD) has recently increased, and maintaining high quality of CKD care is a major factor in preventing…”
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Impacts of Visceral Adipose Tissue and Subcutaneous Adipose Tissue on Metabolic Risk Factors in Middle-aged Japanese by Oka, Rie, Miura, Katsuyuki, Sakurai, Masaru, Nakamura, Koshi, Yagi, Kunimasa, Miyamoto, Susumu, Moriuchi, Tadashi, Mabuchi, Hiroshi, Koizumi, Junji, Nomura, Hideki, Takeda, Yoshiyu, Inazu, Akihiro, Nohara, Atsushi, Kawashiri, Masa-aki, Nagasawa, Shinya, Kobayashi, Junji

“…Regional fat distribution rather than overall fat volume has been considered to be important to understanding the link between obesity and metabolic disorders…”
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Mentoring the next generation of physician-scientists in Japan: a cross-sectional survey of mentees in six academic medical centers by Sakushima, Ken, Mishina, Hiroki, Fukuhara, Shunichi, Sada, Kenei, Koizumi, Junji, Sugioka, Takashi, Kobayashi, Naoto, Nishimura, Masaharu, Mori, Junichiro, Makino, Hirofumi, Feldman, Mitchell D

“…Physician-scientists play key roles in biomedical research across the globe, yet prior studies have found that it is increasingly difficult to recruit and…”
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Reduction of Serum Ubiquinol-10 and Ubiquinone-10 Levels by Atorvastatin in Hypercholesterolemic Patients by Mabuchi, Hiroshi, Higashikata, Toshinori, Kawashiri, Masaaki, Katsuda, Shoji, Mizuno, Mihoko, Nohara, Atsushi, Inazu, Akihiro, Koizumi, Junji, Kobayashi, Junji

“…Reduction of serum cholesterol levels with statin therapy decreases the risk of coronary heart disease. Inhibition of HMG-CoA reductase by statin results in…”
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Diabetes in the elderly by Koizumi, Junji

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Long-term efficacy of low-density lipoprotein apheresis on coronary heart disease in familial hypercholesterolemia by Mabuchi, Hiroshi, Koizumi, Junji, Shimizu, Masami, Kajinami, Kouji, Miyamoto, Susumu, Ueda, Kousei, Takegoshi, Tadayoshi

“…Familial hypercholesterolemia (FH) is characterized by severe hypercholesterolemia and premature coronary heart disease (CHD). The lower the plasma cholesterol…”
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Identification of a Novel Missense Mutation in the Sterol 27-Hydroxylase Gene in Two Japanese Patients with Cerebrotendinous Xanthomatosis by Nozue, Tsuyoshi, Higashikata, Toshinori, Inazu, Akihiro, Kawashiri, Masa-aki, Nohara, Atsushi, Kobayashi, Junji, Koizumi, Junji, Yamagishi, Masakazu, Mabuchi, Hiroshi

“…Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive sterol storage disease caused by a mutated sterol 27-hydroxylase (CYP27A1) gene. We analyzed…”
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Serum lipoprotein lipase mass: Clinical significance of its measurement by Kobayashi, Junji, Nohara, Atsushi, Kawashiri, Masa-aki, Inazu, Akihiro, Koizumi, Junji, Nakajima, Katsuyuki, Mabuchi, Hiroshi

“…Lipoprotein lipase (LPL) is a lipolytic enzyme involved in catalyzing hydrolysis of triglycerides (TG) in chylomicrons and very low-density lipoprotein (VLDL)…”
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Clinical trials of cholesterol lowering for the secondary prevention of coronary heart disease by Koizumi, Junji

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ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects by Miwa, Kenji, Inazu, Akihiro, Kobayashi, Junji, Higashikata, Toshinori, Nohara, Atsushi, Kawashiri, Masaaki, Katsuda, Shoji, Takata, Mutsuko, Koizumi, Junji, Mabuchi, Hiroshi

“…The ratio of serum plant sterols to cholesterol is positively correlated with the fractional cholesterol absorption, whereas serum precursors of cholesterol…”
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Diabetes Progression from "High-Normal" Glucose in School Teachers by Moriuchi, Tadashi, Oka, Rie, Yagi, Kunimasa, Miyamoto, Susumu, Nomura, Hideki, Yamagishi, Masakazu, Mabuchi, Hiroshi, Kobayashi, Junji, Koizumi, Junji

“…Objective High-normal, the intermediate category between normal fasting glucose (NFG) and impaired fasting glucose (IFG), was introduced in the criteria of the…”
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Global Anthropology versus Anthropologies by Koizumi, Junji

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Global Anthropology versus Anthropologies: Comment by Koizumi, Junji

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Extreme Contrast of Postprandial Remnant-Like Particles Formed in Abetalipoproteinemia and Homozygous Familial Hypobetalipoproteinemia by Kawashiri, Masa-aki, Tada, Hayato, Hashimoto, Marowa, Taniyama, Matsuo, Nakano, Takamitsu, Nakajima, Katsuyuki, Inoue, Takeshi, Mori, Mika, Nakanishi, Chiaki, Konno, Tetsuo, Hayashi, Kenshi, Nohara, Atsushi, Inazu, Akihiro, Koizumi, Junji, Ishihara, Hirotaka, Kobayashi, Junji, Hirano, Tsutomu, Mabuchi, Hiroshi, Yamagishi, Masakazu

“…Background: Familial hypobetalipoproteinemia (FHBL) and abetalipoproteinemia (ABL) are rare inherited forms of hypolipidemia. Their differential diagnosis is…”
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Effects of NK-104, a new hydroxymethylglutaryl-coenzyme reductase inhibitor, on low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia by Kajinami, Kouji, Koizumi, Junji, Ueda, Kosei, Miyamoto, Susumu, Takegoshi, Tadayoshi, Mabuchi, Hiroshi

“…The clinical efficacy of NK-104, a novel and totally synthetic hydroxymethylglutaryl-coenzyme A reductase inhibitor, was assessed in 30 patients (men/women =…”
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Efficacy of Colestimide Coadministered With Atorvastatin in Japanese Patients With Heterozygous Familial Hypercholesterolemia (FH) by Kawashiri, Masa-aki, Higashikata, Toshinori, Nohara, Atsushi, Kobayashi, Junji, Inazu, Akihiro, Koizumi, Junji, Mabuchi, Hiroshi

“…Background Colestimide, a 2-methylimidazole-epichlorohydrin polymer, is a new bile-acid-sequestering resin, that is 4-fold as powerful at lowering low-density…”
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Marked Aortic Valve Stenosis Progression After Receiving Long-Term Aggressive Cholesterol-Lowering Therapy Using Low-Density Lipoprotein Apheresis in a Patient With Familial Hypercholesterolemia by Tsuchida, Masayuki, Kawashiri, Masa-aki, Tada, Hayato, Takata, Mutsuko, Nohara, Atsushi, Ino, Hidekazu, Inazu, Akihiro, Kobayashi, Junji, Koizumi, Junji, Mabuchi, Hiroshi, Yamagishi, Masakazu

“…In 1982, a 49-year-old Japanese woman had been referred to our hospital for further investigation of her hypercholesterolemia. She was diagnosed as…”
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Increased High-Density Lipoprotein Levels Caused by a Common Cholesteryl-Ester Transfer Protein Gene Mutation by Inazu, Akihiro, Brown, Maryanne L, Hesler, Charles B, Agellon, Luis B, Koizumi, Junji, Takata, Koki, Maruhama, Yoshisuke, Mabuchi, Hiroshi, Tall, Alan R

“…MOST prospective epidemiologic studies have found an inverse correlation between levels of high-density lipoprotein (HDL) and the incidence of atherosclerotic…”
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Abetalipoproteinemia Caused by Maternal Isodisomy of Chromosome 4q Containing an Intron 9 Splice Acceptor Mutation in the Microsomal Triglyceride Transfer Protein Gene by Yang, Xiao Ping, Inazu, Akihiro, Yagi, Kunimasa, Kajinami, Kouji, Koizumi, Junji, Mabuchi, Hiroshi

“…Uniparental disomy (UPD), a rare inheritance of 2 copies of a single chromosome homolog or a region of a chromosome from one parent, can result in various…”
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