Search Results - "KOI, M"

Naphthyl Tetronic Acids as Multi-Target Inhibitors of Bacterial Peptidoglycan Biosynthesis by Mansour, Tarek S., Caufield, Craig E., Rasmussen, Beth, Chopra, Rajiv, Krishnamurthy, Girija, Morris, Koi M., Svenson, Kristine, Bard, Joel, Smeltzer, Claudia, Naughton, Shaughnessy, Antane, Schuyler, Yang, Youjun, Severin, Anatoly, Quagliato, Dominick, Petersen, Peter J., Singh, Guy

“…A pathway screen targeting multiple muramyl peptide synthesis inhibitors identified the naphthyl tetronic acids series. Optimization of this series based on…”
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A change in microsatellite instability caused by cisplatin-based chemotherapy of ovarian cancer by WATANABE, Y, KOI, M, HEMMI, H, HOSHAI, H, NODA, K

“…To clarify the mechanism of acquired CDDP resistance in ovarian cancer, we compared the microsatellite instability (MSI) by the amplification of 10…”
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Tumor Cell Growth Arrest Caused by Subchromosomal Transferable DNA Fragments from Chromosome 11 by Koi, Minoru, Johnson, Laura A., Kalikin, Linda M., Peter F. R. Little, Nakamura, Yusuke, Feinberg, Andrew P.

“…A fundamental problem in the identification and isolation of tumor suppressor and other growth-inhibiting genes is the loss of power of genetic complementation…”
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Loss of Tumor-Suppressive Function during Chemically Induced Neoplastic Progression of Syrian Hamster Embryo Cells by Koi, M., Barrett, J. Carl

“…Cell hybrids between normal, early-passage Syrian hamster embryo cells and a highly tumorigenic, chemically transformed hamster cell line, BP6T, were formed,…”
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Role of a Tumor-Suppressor Gene in the Negative Control of Anchorage-Independent Growth of Syrian Hamster Cells by Koi, Minoru, Afshari, Cynthia A., Annab, Lois A., Barrett, J. Carl

“…Tumor-suppressor genes control the neoplastic phenotype of tumor cells, but the function of these genes in normal cells is unknown. In this report we show that…”
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Microsatellite instability at tetranucleotide repeats in sporadic colorectal cancer in Japan by YAMADA, Kanae, KANAZAWA, Shinsaku, KOIKE, Junichi, SUGIYAMA, Hisahiko, CAN XU, FUNAHASHI, Kimihiko, RICHARD BOLAND, C, KOI, Minoru, HEMMI, Hiromichi

“…Most tumors of patients with Lynch syndrome and a fraction of sporadic colorectal cancers (CRCs) exhibit high levels of microsatellite instability (MSI) at…”
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Loss of DNA mismatch repair in acquired resistance to cisplatin by AEBI, S, KURDI-HAIDAR, B, HOWELL, S. B, GORDON, R, CENNI, B, ZHENG, H, FINK, D, CHRISTEN, R. D, BOLAND, C. R, KOI, M, FISHEL, R

“…Selection of cells for resistance to cisplatin, a well-recognized mutagen, could result in mutations in genes involved in DNA mismatch repair and thereby to…”
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One-milliliter wet-digestion for inductively coupled plasma mass spectrometry (ICP-MS): determination of platinum-DNA adducts in cells treated with platinum(II) complexes by Yamada, Kanae, Kato, Naoyuki, Takagi, Akimitsu, Koi, Minoru, Hemmi, Hiromichi

“…Platinum (Pt)-DNA adducts formed by the anti-tumor agent cisplatin are recognized by the DNA mismatch repair (MMR) system. To investigate the involvement of…”
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Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation by Koi, M, Umar, A, Chauhan, D P, Cherian, S P, Carethers, J M, Kunkel, T A, Boland, C R

“…The human colon tumor cell line HCT 116 is known to have a homozygous mutation in the mismatch repair gene hMLH1 on human chromosome 3, to exhibit…”
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Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint by HAWN, M. T, ASAD UMAR, CARETHERS, J. M, MARRA, G, KUNKEL, T. A, BOLAND, C. R, KOI, M

“…The human colon tumor cell line HCT116 is deficient in wild-type hMLH1, is defective in mismatch repair (MMR), exhibits microsatellite instability, and is…”
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Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes by Mellon, Isabel, Rajpal, Deepak K., Koi, Minoru, Boland, C. Richard, Champe, Gregory N.

“…Deficiencies in mismatch repair have been linked to a common cancer predisposition syndrome in humans, hereditary nonpolyposis colorectal cancer (HNPCC), and a…”
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Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6 by UMAR, A, KOI, M, RISINGER, J. I, GLAAB, W. E, TINDALL, K. R, KOLODNER, R. D, BOLAND, C. R, BARRETT, J. C, KUNKEL, T. A

“…The human DNA mismatch repair genes hMSH2 and hMSH6 encode the proteins that, together, bind to mismatches to initiate repair of replication errors. Human…”
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Microsatellite Status and Immunohistochemical Features of Ovarian Clear-cell Carcinoma by UEDA, Haruhiko, WATANABE, Yoh, NAKAI, Hidekatsu, HEMMI, Hiromichi, KOI, Minoru, HOSHIAI, Hiroshi

“…Background: Ovarian clear-cell carcinoma (OCC) is known to have a poor prognosis and selected genetic features of OCC remain unknown. We investigated…”
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Kinetic Study for the Reactions of Si Atoms with SiH4 by Koi, Makoto, Tonokura, Kenichi, Tezaki, Atsumu, Koshi, Mitsuo

“…Rate constants for the reactions of Si (3P, 1D, and 1S) atoms with SiH4 have been determined using a combined laser photolysis/laser induced fluorescence…”
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Unipolar morphology–guided critical isthmus emphasis in a patient with scar-related ventricular tachycardia by Kataoka, Naoya, Imamura, Teruhiko, Uchida, Keisuke, Koi, Takahisa, Kinugawa, Koichiro

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Restoration of radiation resistance in ataxia telangiectasia cells by the introduction of normal human chromosome 11 by Komatsu, K, Kodama, S, Okumura, Y, Koi, M, Oshimura, M

“…In order to identify the human chromosome which carries a mutated gene in cells from a patient with the hereditary disorder ataxia telangiectasia belonging to…”
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Two-step chromosomal control of tumorigenicity of Chinese hamster cells in nude mice by Ebina, T, Koi, M, Ishida, N

“…A simple method for microinjecting isolated chromosomes into a single living cell under an inverted microscope has been developed. Of the 368 injected cells,…”
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A Novel Concept for Americium-containing Target for Use in Fast Reactors by OSAKA, Masahiko, KOI, Mamoru, TAKANO, Sho, YAMANE, Yoshihiro, MISAWA, Tsuyoshi

“…A novel concept for the americium-containing target, which consists of (Th,Am)O2-x and molybdenum support material, is proposed that can fulfill several…”
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Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine by Carethers, J M, Hawn, M T, Chauhan, D P, Luce, M C, Marra, G, Koi, M, Boland, C R

“…The phenomenon of alkylation tolerance has been observed in cells that are deficient in some component of the DNA mismatch repair (MMR) system. An…”
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Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors by Takahashi, Tomonori, Min, Zhenghua, Uchida, Iichiro, Arita, Michitsune, Watanabe, Yoh, Koi, Minoru, Hemmi, Hiromichi

“…We studied the cytotoxic effects of various DNA replication inhibitors on MMR-deficient and -proficient colon carcinoma cell lines. DNA polymerase (pol)…”
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