Search Results - "KOHNO, Kakeru"

A Redox-Silent Analogue of Tocotrienol May Break the Homeostasis of Proteasomes in Human Malignant Mesothelioma Cells by Inhibiting STAT3 and NRF1 by Ishii, Kyota, Fusegi, Momoka, Mori, Tatsuki, Teshima, Kosuke, Ninomiya, Nanako, Kohno, Kakeru, Sato, Ayami, Ishida, Tatsuya, Miyakoshi, Yuichi, Yano, Tomohiro

“…6- -Carboxypropyl-alpha-tocotrienol (α-T3E) is a multi-target redox-silent analogue of tocotrienol that exhibits cytotoxicity against many cancer cells,…”
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Endocrine secretory granule production is caused by a lack of REST and intragranular secretory content and accelerated by PROX1 by Ishii, Jun, Sato-Yazawa, Hanako, Kashiwagi, Korehito, Nakadate, Kazuhiko, Iwamoto, Masami, Kohno, Kakeru, Miyata-Hiramatsu, Chie, Masawa, Meitetsu, Onozaki, Masato, Noda, Shuhei, Miyazawa, Tadasuke, Takagi, Megumi, Yazawa, Takuya

“…Endocrine secretory granules (ESGs) are morphological characteristics of endocrine/neuroendocrine cells and store peptide hormones/neurotransmitters. ESGs…”
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Tocotrienol-rich fraction from annatto ameliorates expression of lysyl oxidase in human osteoblastic MG-63 cells by Kohno, Kakeru, Yamada, Wakana, Ishitsuka, Aya, Sekine, Miki, Virgona, Nantiga, Ota, Masako, Yano, Tomohiro

“…Lysyl oxidase (LOX) is required for the formation of bone collagen cross-links. Inactivation of the LOX gene in osteoblasts by DNA methylation and JAK…”
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Combination Effect of Bowman-Birk Inhibitor and α-Tocopheryl Succinate on Prostate Cancer Stem-Like Cells by KANEKO, Saki, YAMAZAKI, Takumi, KOHNO, Kakeru, SATO, Ayami, KATO, Kazunori, YANO, Tomohiro

“…The reoccurrence of androgen-dependent prostate cancer after anti-androgen therapy mainly depends on prostate cancer stem-like cells. To reduce the risk, it is…”
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A Succinate Ether Derivative of Tocotrienol Enhances Dickkopf-1 Gene Expression through Epigenetic Alterations in Malignant Mesothelioma Cells by Sato, Ayami, Ueno, Haruka, Fusegi, Momoka, Kaneko, Saki, Kohno, Kakeru, Virgona, Nantiga, Ando, Akira, Sekine, Yuko, Yano, Tomohiro

“…Wnt signaling plays an essential role in tumor cell growth, including the development of malignant mesothelioma (MM). Epigenetic silencing of negative Wnt…”
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REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma by Masawa, Meitetsu, Sato-Yazawa, Hanako, Kashiwagi, Korehito, Ishii, Jun, Miyata-Hiramatsu, Chie, Iwamoto, Masami, Kohno, Kakeru, Miyazawa, Tadasuke, Onozaki, Masato, Noda, Shuhei, Shimizu, Yasuo, Niho, Seiji, Yazawa, Takuya

“…Although recent reports have revealed the importance of the inactivation of both RB1 and TP53 in the transformation from lung adenocarcinoma into…”
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LXRβ Activation Inhibits the Proliferation of Small-cell Lung Cancer Cells by Depleting Cellular Cholesterol by Kashiwagi, Korehito, Sato-Yazawa, Hanako, Ishii, Jun, Kohno, Kakeru, Tatsuta, Isaaki, Miyazawa, Tadasuke, Takagi, Megumi, Chiba, Hideki, Yazawa, Takuya

“…Liver X receptors (LXRs) are nuclear receptors with various functions, including the regulation of cholesterol metabolism, glucose homeostasis, and…”
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