Search Results - "KOHNER, E. M"

Microvascular disease: what does the UKPDS tell us about diabetic retinopathy? by Kohner, E. M.

“…Background  The UK Prospective Diabetes Study (UKPDS) was a randomised controlled clinical study which looked at the effect of improved blood glucose and blood…”
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UKPDS 50 : Risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis by STRATTON, I. M, KOHNER, E. M, ALDINGTON, S. J, TURNER, R. C, HOLMAN, R. R, MANLEY, S. E, MATTHEWS, D. R

“…To determine risk factors related to the incidence and progression of diabetic retinopathy over 6 years from diagnosis of Type II (non-insulin-dependent)…”
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Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy by Kohner, E. M., Patel, V., Rassam, S. M.

“…Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy. E M Kohner , V Patel and S M Rassam Royal Postgraduate Medical…”
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Methodology for retinal photography and assessment of diabetic retinopathy : the EURODIAB IDDM Complications Study by ALDINGTON, S. J, KOHNER, E. M, MEUER, S, KLEIN, R, SJØLIE, A. K

“…We present the methodology for 45 degrees retinal photography and detail the development, application and validation of a new system of 45 degrees field…”
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Microaneurysms in the development of diabetic retinopathy (UKPDS 42) by KOHNER, E. M, STRATTON, I. M, ALDINGTON, S. J, TURNER, R. C, MATTHEWS, D. R

“…Aims/hypothesis. To determine whether microaneurysms, in the absence of other lesions, have a predictive role in the progression of diabetic retinopathy in…”
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Clinical validation of a link between TNF-α and the glycosylation enzyme core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy by BEN-MAHMUD, B. M, CHAN, W. H, ABDULAHAD, R. M, DATTI, A, ORLACCHIO, A, KOHNER, E. M, CHIBBER, R

“…Increasing evidence suggests that chronic, subclinical inflammation plays an important role in the pathogenesis of diabetic retinopathy. We recently reported…”
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Markers of insulin resistance are strong risk factors for Retinopathy incidence in Type 1 diabetes: The EURODIAB Prospective Complications Study by CHATURVEDI, Nish, SJOELIE, Anne-Katrin, PORTA, Massimo, ALDINGTON, Steven J, FULLER, John H, SONGINI, Marco, KOHNER, Eva M

“…To determine the incidence of retinopathy and the relative importance of its risk factors in type 1 diabetes. This is a 7.3-year follow-up of 764 of 1,215…”
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Toxic action of advanced glycation end products on cultured retinal capillary pericytes and endothelial cells : relevance to diabetic retinopathy by CHIBBER, R, MOLINATTI, P. A, ROSATTO, N, LAMBOURNE, B, KOHNER, E. M

“…The toxic effects of advanced glycation end products (AGEs) on bovine retinal capillary pericytes (BRP) and endothelial cells (BREC) were studied. AGE-modified…”
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Quality assurance for diabetic retinopathy telescreening by Schneider, S., Aldington, S. J., Kohner, E. M., Luzio, S., Owens, D. R., Schmidt, V., Schuell, H., Zahlmann, G.

“…Aims  TOSCA was an EU‐Commission supported international research project designed to develop telescreening services in diabetic retinopathy and glaucoma. This…”
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Relationship between the severity of retinopathy and progression to photocoagulation in patients with Type 2 diabetes mellitus in the UKPDS (UKPDS 52) by Group, Uk Prospective Diabetes Study (ukpds), Kohner, E. M., Stratton, I. M., Aldington, S. J., Holman, R. R., Matthews, D. R.

“…Summary Aim  to establish the degree to which the severity of retinopathy determines the risk for the need for subsequent photocoagulation in those with newly…”
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Why some cases of retinopathy worsen when diabetic control improves by Chantelau, E, Kohner, E M

“…Doctors have decided that worsening retinopathy is not a reason to withhold intensive insulin treatment, if the insulin improves the diabetic problem…”
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Effect of isovolaemic haemodilution on visual outcome in branch retinal vein occlusion by Chen, Hean C, Wiek, Jutta, Gupta, Anita, Luckie, Alan, Kohner, Eva M

“…AIMS To assess the efficacy of isovolaemic haemodilution therapy (IHT) in the treatment of patients with branch retinal vein occlusion (BRVO). METHODS Patients…”
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The effect of growth hormone (GH) replacement therapy in adult patients with type 1 diabetes mellitus and GH deficiency by Christ, E. R., Simpson, H. L., Breen, L., Russell-Jones, D. L., Kohner, E. M.

“…Summary objectives Specific problems in patients with insulin‐dependent diabetes mellitus (IDDM) and GH deficiency are hypoglycaemic attacks, increased insulin…”
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Retinal blood flow changes during pregnancy in women with diabetes by Chen, HC, Newsom, RS, Patel, V, Cassar, J, Mather, H, Kohner, EM

“…To study retinal blood flow (RBF) during pregnancy in subjects with and without diabetes and to relate the changes to progression in diabetic retinopathy. RBF…”
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The effect of experimental hypertension on retinal vascular autoregulation in humans: a mechanism for the progression of diabetic retinopathy by Rassam, S M, Patel, V, Kohner, E M

“…Since the retinal vessels have no sympathetic innervation, blood flow in response to raised blood pressure is dependent on autoregulation. To determine the…”
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Activity of the glycosylating enzyme, core 2 GlcNAc (beta1,6) transferase, is higher in polymorphonuclear leukocytes from diabetic patients compared with age-matched control subjects: relevance to capillary occlusion in diabetic retinopathy by Chibber, R, Ben-Mahmud, B M, Coppini, D, Christ, E, Kohner, E M

“…Activity of the glycosylating enzyme, core 2 GlcNAc (beta1,6) transferase, is higher in polymorphonuclear leukocytes from diabetic patients compared with…”
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Autoregulation in the Human Retinal Circulation: Assessment Using Isometric Exercise, Laser Doppler Velocimetry, and Computer-Assisted Image Analysis by Dumskyj, Martin J., Eriksen, Jesper E., Doré, Caroline J., Kohner, Eva M.

“…Autoregulation of blood flow in response to changes in perfusion pressure is known to occur in a number of tissues including the human retina. Defective…”
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Accurate vessel width measurement from fundus photographs: a new concept by Rassam, S M, Patel, V, Brinchmann-Hansen, O, Engvold, O, Kohner, E M

“…Accurate determination of retinal vessel width measurement is important in the study of the haemodynamic changes that accompany various physiological and…”
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Raised serum apolipoprotein (a) in active diabetic retinopathy by MAIOLI, M, TONOLO, G, PACIFICO, A, CICCARESE, M, BRIZZI, P, KOHNER, E. M, PORTA, M

“…Progressive capillary occlusion often leads to severe retinopathy within 15-20 years of the onset of Type 1 (insulin-dependent) diabetes mellitus…”
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Intracellular protein glycation in cultured retinal capillary pericytes and endothelial cells exposed to high-glucose concentration by Chibber, R, Molinatti, P A, Kohner, E M

“…There is now increasing evidence suggesting that non-enzymatic glycation (NEG) of proteins is involved in the pathogenesis of chronic diabetic complication. In…”
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