Search Results - "KOHN, D"

Classifications in Brief: Kellgren-Lawrence Classification of Osteoarthritis by Kohn, Mark D., Sassoon, Adam A., Fernando, Navin D.

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A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency by Hacein-Bey-Abina, Salima, Pai, Sung-Yun, Gaspar, H. Bobby, Armant, Myriam, Berry, Charles C, Blanche, Stephane, Bleesing, Jack, Blondeau, Johanna, de Boer, Helen, Buckland, Karen F, Caccavelli, Laure, Cros, Guilhem, De Oliveira, Satiro, Fernández, Karen S, Guo, Dongjing, Harris, Chad E, Hopkins, Gregory, Lehmann, Leslie E, Lim, Annick, London, Wendy B, van der Loo, Johannes C.M, Malani, Nirav, Male, Frances, Malik, Punam, Marinovic, M. Angélica, McNicol, Anne-Marie, Moshous, Despina, Neven, Benedicte, Oleastro, Matías, Picard, Capucine, Ritz, Jerome, Rivat, Christine, Schambach, Axel, Shaw, Kit L, Sherman, Eric A, Silberstein, Leslie E, Six, Emmanuelle, Touzot, Fabien, Tsytsykova, Alla, Xu-Bayford, Jinhua, Baum, Christopher, Bushman, Frederic D, Fischer, Alain, Kohn, Donald B, Filipovich, Alexandra H, Notarangelo, Luigi D, Cavazzana, Marina, Williams, David A, Thrasher, Adrian J

“…Correction of the genetic lesion leading to X-linked SCID with first-generation retroviral vectors has been associated with a 25% risk of acute leukemia. A…”
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Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells by Ueno, Shuichi, Weidinger, Gilbert, Osugi, Tomoaki, Kohn, Aimee D, Golob, Jonathan L, Pabon, Lil, Reinecke, Hans, Moon, Randall T, Murry, Charles E

“…Understanding pathways controlling cardiac development may offer insights that are useful for stem cell-based cardiac repair. Developmental studies indicate…”
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Selective bundle tensioning in double-bundle MPFL reconstruction to improve restoration of dynamic patellofemoral contact pressure by Zumbansen, N., Haupert, A., Kohn, D., Lorbach, O.

“…Purpose To evaluate the optimal graft tension angles in a medial patellofemoral ligament (MPFL) reconstruction with selective bundle tensioning in order to…”
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Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype by Meyer-Lindenberg, Andreas, Kohn, Philip D, Kolachana, Bhaskar, Kippenhan, Shane, McInerney-Leo, Aideen, Nussbaum, Robert, Weinberger, Daniel R, Berman, Karen Faith

“…Using multimodal neuroimaging in humans, we demonstrate specific interactions between prefrontal activity and midbrain dopaminergic synthesis. A common…”
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PET-measured human dopamine synthesis capacity and receptor availability predict trading rewards and time-costs during foraging by Ianni, Angela M., Eisenberg, Daniel P., Boorman, Erie D., Constantino, Sara M., Hegarty, Catherine E., Gregory, Michael D., Masdeu, Joseph C., Kohn, Philip D., Behrens, Timothy E., Berman, Karen F.

“…Foraging behavior requires weighing costs of time to decide when to leave one reward patch to search for another. Computational and animal studies suggest that…”
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Wnt and calcium signaling: β-Catenin-independent pathways by Kohn, Aimee D., Moon, Randall T.

“…Wnt signaling is a complex pathway in which β-catenin is typically viewed as a central mediator. However, within the past 15 years, at least three Wnt-mediated…”
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Tissue engineering: state of the art in oral rehabilitation by SCHELLER, E. L., KREBSBACH, P. H., KOHN, D. H.

“…Summary  More than 85% of the global population requires repair or replacement of a craniofacial structure. These defects range from simple tooth decay to…”
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Alterations of the subchondral bone in osteochondral repair--translational data and clinical evidence by Orth, P, Cucchiarini, M, Kohn, D, Madry, H

“…Alterations of the subchondral bone are pathological features associated with spontaneous osteochondral repair following an acute injury and with articular…”
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A Novel Thyroid Stimulating Immunoglobulin Bioassay Is a Functional Indicator of Activity and Severity of Graves’ Orbitopathy by Lytton, S. D., Ponto, K. A., Kanitz, M., Matheis, N., Kohn, L. D., Kahaly, G. J.

“…Context: Immunoglobulins stimulating the TSH receptor (TSI) influence thyroid function and likely mediate extrathyroidal manifestations of Graves’ disease…”
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Evidence for Abnormal Cortical Functional Connectivity During Working Memory in Schizophrenia by Meyer-Lindenberg, Andreas, Poline, Jean-Baptiste, Kohn, Philip D., Holt, John L., Egan, Michael F., Weinberger, Daniel R., Berman, Karen Faith

“…OBJECTIVE: Disturbed neuronal interactions may be involved in schizophrenia because it is without clear regional pathology. Aberrant connectivity is further…”
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Translating Dental, Oral, and Craniofacial Regenerative Medicine Innovations to the Clinic through Interdisciplinary Commercial Translation Architecture by Taylor, D.P., Yoshida, M., Fuller, K., Giannobile, W.V., Sfeir, C.S., Wagner, W.R., Kohn, D.H.

“…Few university-based regenerative medicine innovations in the dental, oral, and craniofacial (DOC) space have been commercialized and affected clinical…”
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Differences in fixation stability between spacer plate and plate fixator following high tibial osteotomy by Pape, D., Kohn, D., van Giffen, N., Hoffmann, A., Seil, R., Lorbach, O.

“…Purpose Since in vivo stability following high tibial osteotomy is unknown, surgeons customize the postoperative rehabilitation to the assumed implant…”
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Phenylmethimazole Decreases Toll-Like Receptor 3 and Noncanonical Wnt5a Expression in Pancreatic Cancer and Melanoma Together with Tumor Cell Growth and Migration by Schwartz, Anthony L, Malgor, Ramiro, Dickerson, Eric, Weeraratna, Ashani T, Slominski, Andrzej, Wortsman, Jacobo, Harii, Norikazu, Kohn, Aimee D, Moon, Randall T, Schwartz, Frank L, Goetz, Douglas J, Kohn, Leonard D, McCall, Kelly D

“…Purpose: To evaluate whether ( a ) Wnt5a expression in pancreatic cancer and malignant melanoma cells might be associated with constitutive levels of Toll-like…”
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The NIMH Intramural Longitudinal Study of the Endocrine and Neurobiological Events Accompanying Puberty: Protocol and rationale for methods and measures by Cole, Katherine M., Wei, Shau-Ming, Martinez, Pedro E., Nguyen, Tuong-Vi, Gregory, Michael D., Kippenhan, J. Shane, Kohn, Philip D., Soldin, Steven J., Nieman, Lynnette K., Yanovski, Jack A., Schmidt, Peter J., Berman, Karen F.

“…•Reviews the relevance of puberty and gonadal sex steroids in human neurodevelopment.•Details the protocol and rationale of our ongoing longitudinal…”
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Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies by Chen, Gang, Nash, Tiffany A., Cole, Katherine M., Kohn, Philip D., Wei, Shau-Ming, Gregory, Michael D., Eisenberg, Daniel P., Cox, Robert W., Berman, Karen F., Shane Kippenhan, J.

“…The ubiquitous adoption of linearity for quantitative predictors in statistical modeling is likely attributable to its advantages of straightforward…”
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Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain by Gregory, Michael D., Kippenhan, J. Shane, Eisenberg, Daniel P., Kohn, Philip D., Dickinson, Dwight, Mattay, Venkata S., Chen, Qiang, Weinberger, Daniel R., Saad, Ziad S., Berman, Karen F.

“…Before their disappearance from the fossil record approximately 40,000 years ago, Neanderthals, the ancient hominin lineage most closely related to modern…”
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Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia by Meyer-Lindenberg, Andreas, Miletich, Robert S, Kohn, Philip D, Esposito, Giuseppe, Carson, Richard E, Quarantelli, Mario, Weinberger, Daniel R, Berman, Karen Faith

“…Both dopaminergic neurotransmission and prefrontal cortex (PFC) function are known to be abnormal in schizophrenia. To test the hypothesis that these phenomena…”
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Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells by Woll, Petter S., Morris, Julie K., Painschab, Matt S., Marcus, Rebecca K., Kohn, Aimee D., Biechele, Travis L., Moon, Randall T., Kaufman, Dan S.

“…Human embryonic stem cells (hESCs) provide an important means to effectively study soluble and cell-bound mediators that regulate development of early blood…”
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Parathyroid hormone [1-34] improves articular cartilage surface architecture and integration and subchondral bone reconstitution in osteochondral defects in vivo by Orth, P, Cucchiarini, M, Zurakowski, D, Menger, M.D, Kohn, D.M, Madry, H

“…Summary Objective The 1-34 amino acid segment of the parathyroid hormone (PTH [1-34]) mediates anabolic effects in chondrocytes and osteocytes. The aim of this…”
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