Search Results - "KOHBERGER, Robert"

Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial by Bhandari, Nita, PhD, Rongsen-Chandola, Temsunaro, MSc, Bavdekar, Ashish, DNB, John, Jacob, MD, Antony, Kalpana, MBA, Taneja, Sunita, PhD, Goyal, Nidhi, DPH, Kawade, Anand, MD, Kang, Gagandeep, Prof, Rathore, Sudeep Singh, MBBS, Juvekar, Sanjay, PhD, Muliyil, Jayaprakash, Prof, Arya, Alok, MPharm, Shaikh, Hanif, MPharm, Abraham, Vinod, MPH, Vrati, Sudhanshu, Prof, Proschan, Michael, PhD, Kohberger, Robert, PhD, Thiry, Georges, PhD, Glass, Roger, PhD, Greenberg, Harry B, Prof, Curlin, George, MD, Mohan, Krishna, PhD, Harshavardhan, G V J A, BVSc, Prasad, Sai, MBA, Rao, T S, PhD, Boslego, John, MD, Bhan, Maharaj Kishan, Dr Prof

“…Summary Background Rotavirus is the most common cause of severe dehydrating gastroenteritis in developing countries. Safe, effective, and affordable rotavirus…”
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Protective efficacy of a trivalent recombinant hemagglutinin protein vaccine (FluBlok® ) against influenza in healthy adults: A randomized, placebo-controlled trial by Treanor, John J, Sahly, Hana El, King, James, Graham, Irene, Izikson, Ruvim, Kohberger, Robert, Patriarca, Peter, Cox, Manon

“…Highlights ► Randomized, placebo-controlled, multicenter assessment of efficacy of baculovirus expressed hemagglutinin vaccine for prevention of…”
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Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies by Siber, George R, Chang, Ih, Baker, Sherryl, Fernsten, Philip, O’Brien, Katherine L, Santosham, Mathuram, Klugman, Keith P, Madhi, Shabir A, Paradiso, Peter, Kohberger, Robert

“…Abstract Estimates of minimum protective antibody concentrations for vaccine preventable diseases are of critical importance in assessing whether new vaccines…”
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Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media by Eskola, Juhani, Kilpi, Terhi, Palmu, Arto, Jokinen, Jukka, Eerola, Mervi, Haapakoski, Jaason, Herva, Elja, Takala, Aino, Käyhty, Helena, Karma, Pekka, Kohberger, Robert, Lockhart, Stephen, Siber, George, Mäkelä, P. Helena

“…Acute otitis media in children accounts for 20 million office visits per year in the United States, and 18 percent of ambulatory care visits among preschool…”
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Prediction of pertussis vaccine efficacy using a correlates of protection model by Kohberger, Robert C, Jemiolo, David, Noriega, Fernando

“…Abstract A previously developed statistical model relates vaccine immune responses to protection against pertussis disease in a household contact setting…”
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Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants by Jódar, Luis, Butler, Jay, Carlone, George, Dagan, Ron, Goldblatt, David, Käyhty, Helena, Klugman, Keith, Plikaytis, Brian, Siber, George, Kohberger, Robert, Chang, Ih, Cherian, Thomas

“…The World Health Organization (WHO) is undertaking a series of consultations on serological criteria for the evaluation and licensure of new…”
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Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children by BLACK, STEVEN, SHINEFIELD, HENRY, FIREMAN, BRUCE, LEWIS, EDWIN, RAY, PAULA, HANSEN, JOHN R, ELVIN, LAURA, ENSOR, KATHY M, HACKELL, JILL, SIBER, GEORGE, MALINOSKI, FRANK, MADORE, DACE, CHANG, IH, KOHBERGER, ROBERT, WATSON, WENDY, AUSTRIAN, ROBERT, EDWARDS, KATHY

“…OBJECTIVE. METHODS. RESULTS.In the interim analysis in August, 1998, 17 of the 17 cases of invasive disease caused by vaccine serotype in fully vaccinated…”
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Comments on 'Sample size for equivalence trials: A case study from a vaccine lot consistency trial' by J. Ganju, A. Izu and A. Anemona, Statistics in Medicine 2008; 27:3743-3754 by Kohberger, Robert C.

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Type I Error and Power in Noninferiority/Equivalence Trials with Correlated Multiple Endpoints: An Example from Vaccine Development Trials by Kong, Lan, Kohberger, Robert C., Koch, Gary G.

“…Clinical trials necessary for the development of new treatment often require testing of multiple endpoints for equivalence or noninferiority relative to an…”
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Evaluation of safety and immunogenicity of recombinant influenza hemagglutinin (H5/Indonesia/05/2005) formulated with and without a stable oil-in-water emulsion containing glucopyranosyl-lipid A (SE + GLA) adjuvant by Treanor, John J, Essink, Brandon, Hull, Steven, Reed, Steven, Izikson, Ruvim, Patriarca, Peter, Goldenthal, Karen L, Kohberger, Robert, Dunkle, Lisa M

“…Highlights • We evaluated baculovirus-expressed recombinant H5 hemagglutinin vaccine with the adjuvant GLE/SE. • Adjuvanted vaccine was substantially more…”
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A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection by Klugman, Keith P, Madhi, Shabir A, Huebner, Robin E, Kohberger, Robert, Mbelle, Nontombi, Pierce, Nathaniel

“…This controlled trial involving 39,836 children evaluated the efficacy of a 9-valent pneumococcal conjugate vaccine in South Africa. Vaccination decreased the…”
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Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian children in the second year of life by Bhandari, Nita, Rongsen-Chandola, Temsunaro, Bavdekar, Ashish, John, Jacob, Antony, Kalpana, Taneja, Sunita, Goyal, Nidhi, Kawade, Anand, Kang, Gagandeep, Rathore, Sudeep Singh, Juvekar, Sanjay, Muliyil, Jayaprakash, Arya, Alok, Shaikh, Hanif, Abraham, Vinod, Vrati, Sudhanshu, Proschan, Michael, Kohberger, Robert, Thiry, Georges, Glass, Roger, Greenberg, Harry B, Curlin, George, Mohan, Krishna, Harshavardhan, G.V.J.A, Prasad, Sai, Rao, T.S, Boslego, John, Bhan, Maharaj Kishan

“…Highlights • Efficacy of 116E against severe RVGE sustained in the second year of life. • Protection of 116E increased with greater severity of RV associated…”
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Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: group randomised trial by O'Brien, Katherine L, Moulton, Lawrence H, Reid, Raymond, Weatherholtz, Robert, Oski, Jane, Brown, Laura, Kumar, Gaurav, Parkinson, Alan, Hu, Diana, Hackell, Jill, Chang, Ih, Kohberger, Robert, Siber, George, Santosham, Mathuram

“…Streptococcus pneumoniae is the main cause of invasive bacterial disease in children aged younger than 2 years. Navajo and White Mountain Apache children have…”
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Anthrax vaccine-induced antibodies provide cross-species prediction of survival to aerosol challenge by Fay, Michael P, Follmann, Dean A, Lynn, Freyja, Schiffer, Jarad M, Stark, Gregory V, Kohberger, Robert, Quinn, Conrad P, Nuzum, Edwin O

“…Because clinical trials to assess the efficacy of vaccines against anthrax are not ethical or feasible, licensure for new anthrax vaccines will likely involve…”
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Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile by Picard, Michele D, Bodmer, Jean-Luc, Gierahn, Todd M, Lee, Alexander, Price, Jessica, Cohane, Kenya, Clemens, Veronica, DeVault, Victoria L, Gurok, Galina, Kohberger, Robert, Higgins, Darren E, Siber, George R, Flechtner, Jessica Baker, Geisler, William M

“…Chlamydia trachomatis is the causative agent of the most frequently reported bacterial sexually transmitted infection, the total burden of which is…”
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Serum Serotype-Specific Pneumococcal Anticapsular Immunoglobulin G Concentrations after Immunization with a 9-Valent Conjugate Pneumococcal Vaccine Correlate with Nasopharyngeal Acquisition of Pneumococcus by Dagan, Ron, Givon-Lavi, Noga, Fraser, Drora, Lipsitch, Marc, Siber, George R., Kohberger, Robert

“…BackgroundImmunization with pneumococcal conjugate vaccines (PCVs) reduces nasopharyngeal colonization by Streptococcus pneumoniae. We attempted to correlate…”
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Predictive models and correlates of protection for testing biodefence vaccines by Williamson, E Diane, Duchars, M G, Kohberger, Robert

“…The identification of immune correlates of protection is becoming increasingly important in order to derive a quantitative assessment of the benefit conferred…”
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Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian children in the second year of life: Rotavirus in India: An update on epidemiology and vaccines by BHANDARI, Nita, RONGSEN-CHANDOLA, Temsunaro, JUVEKAR, Sanjay, MULIYIL, Jayaprakash, ARYA, Alok, SHAIKH, Hanif, ABRAHAM, Vinod, VRATI, Sudhanshu, PROSCHAN, Michael, KOHBERGER, Robert, THIRY, Georges, GLASS, Roger, BAVDEKAR, Ashish, GREENBERG, Harry B, CURLIN, George, MOHAN, Krishna, HARSHAVARDHAN, G. V. J. A, PRASAD, Sai, RAO, T. S, BOSLEGO, John, MAHARAJ KISHAN BHAN, JOHN, Jacob, ANTONY, Kalpana, TANEJA, Sunita, GOYAL, Nidhi, KAWADE, Anand, KANG, Gagandeep, SUDEEP SINGH RATHORE

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Safety, Efficacy, and Immunogenicity of 2 Doses of Bovine-Human (UK) and Rhesus–Rhesus-Human Rotavirus Reassortant Tetravalent Vaccines in Finnish Children by Vesikari, Timo, Karvonen, Aino V., Majuri, Jukka, Zeng, Shang-Qin, Pang, Xiao-Li, Kohberger, Robert, Forrest, Bruce D., Hoshino, Yasutaka, Chanock, Robert M., Kapikian, Albert Z.

“…BackgroundLive oral rhesus–rhesus-human rotavirus reassortant tetravalent (RRV-TV) vaccine was efficacious against rotavirus gastroenteritis but was withdrawn…”
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Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers by SHINEFIELD, HENRY R, BLACK, STEVEN, RAY, PAULA, CHANG, IH, LEWIS, NED, FIREMAN, BRUCE, HACKELL, JILL, PARADISO, PETER R, SIBER, GEORGE, KOHBERGER, ROBERT, MADORE, DACE V, MALINOWSKI, FRANK J, KIMURA, ALAN, LE, CHINH, LANDAW, IRENE, AGUILAR, JANET, HANSEN, JOHN

“…OBJECTIVES.The objectives of this study were (1) to determine the safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate (PNCRM7) vaccine in…”
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