Search Results - "KOH, SANG SEOK"
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A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness
Published in Nature communications (16-12-2015)“…The switch between stem/progenitor cell expansion and differentiation is critical for organ homeostasis. The mammalian Hippo pathway effector and oncoprotein…”
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2
Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor
Published in Experimental & molecular medicine (01-03-2021)“…Cancer cachexia is a highly debilitating condition characterized by weight loss and muscle wasting that contributes significantly to the morbidity and…”
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3
Translocalization of enhanced PKM2 protein into the nucleus induced by cancer upregulated gene 2 confers cancer stem cell-like phenotypes
Published in BMB reports (2022)“…Increased mRNA levels of cancer upregulated gene (CUG)2 have been detected in many different tumor tissues using Affymetrix microarray. Oncogenic capability of…”
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4
Pancreatic adenocarcinoma up‐regulated factor (PAUF), a novel up‐regulated secretory protein in pancreatic ductal adenocarcinoma
Published in Cancer science (01-05-2009)“…The identification of novel tumor‐specific proteins or antigens is of great importance for diagnostic and therapeutic applications in pancreatic cancer. Using…”
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5
Identification of novel universal housekeeping genes by statistical analysis of microarray data
Published in Journal of biochemistry and molecular biology (31-03-2007)“…Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase…”
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6
PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway
Published in International journal of molecular sciences (27-09-2022)“…PAUF, a tumor-promoting protein secreted by cancer cells, exerts paracrine effects on immune cells through TLR4 receptors expressed on immune cell surfaces…”
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7
Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells
Published in Carcinogenesis (New York) (01-03-2013)“…Collagen triple helix repeat containing-1 (CTHRC1) is a secreted protein involved in vascular remodeling, bone formation and developmental morphogenesis…”
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8
Phosphofructokinase 1 Platelet Isoform Promotes β-Catenin Transactivation for Tumor Development
Published in Frontiers in oncology (05-03-2020)“…Metabolism plays a critical role in direct regulation of a variety of cellular activities via metabolic enzymes and metabolites. Here, we demonstrate that…”
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9
Translocalization of enhanced PKM2 protein into the nucleus induced by cancer upregulated gene 2 confers cancer stem cell-like phenotypes
Published in BMB reports (28-02-2022)“…Increased mRNA levels of cancer upregulated gene (CUG)2 have been detected in many different tumor tissues using Affymetrix microarray. Oncogenic capability of…”
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10
PAUF as a Target for Treatment of High PAUF-Expressing Ovarian Cancer
Published in Frontiers in pharmacology (06-05-2022)“…Pancreatic adenocarcinoma up-regulated factor (PAUF) plays an important role in tumor growth, metastasis, and immune evasion in the pancreatic tumor…”
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11
Claudin-4 overexpression is associated with epigenetic derepression in gastric carcinoma
Published in Laboratory investigation (01-11-2011)“…The tight junction (TJ) protein claudin-4 is aberrantly upregulated in gastric cancer, but its clinical significance and the molecular mechanisms underlying…”
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12
Monocarboxylate transporter 9 (MCT9) is down‐regulated in renal cell carcinoma
Published in Genes & genomics (01-04-2021)“…Background The renal cell carcinoma (RCC) incidences are continuously increasing, however, their proper characterization remains difficult. Mammalian kidneys…”
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13
NDR1 modulates the UV-induced DNA-damage checkpoint and nucleotide excision repair
Published in Biochemical and biophysical research communications (05-06-2015)“…Nucleotide excision repair (NER) is the sole mechanism of UV-induced DNA lesion repair in mammals. A single round of NER requires multiple components including…”
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14
Identification of novel reference genes using multiplatform expression data and their validation for quantitative gene expression analysis
Published in PloS one (07-07-2009)“…Normalization of mRNA levels using endogenous reference genes (ERGs) is critical for an accurate comparison of gene expression between different samples…”
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15
Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells
Published in International journal of oncology (01-04-2014)“…During the screening of natural chemicals that can reverse multidrug resistance in human A549 lung cancer cells resistant to etoposide (A549RT-eto), we…”
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16
Newly identified tumor-associated role of human Sharpin
Published in Molecular and cellular biochemistry (01-07-2010)“…In order to discover previously unidentified cancer-associated genes, we analyzed genome-wide differences in gene expression between tumor biopsies and normal…”
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17
Remodeling of yeast genome expression in response to environmental changes
Published in Molecular biology of the cell (01-02-2001)“…We used genome-wide expression analysis to explore how gene expression in Saccharomyces cerevisiae is remodeled in response to various changes in extracellular…”
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18
Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer
Published in Oncotarget (09-08-2016)“…Pancreatic cancer is characterized by an immunosuppressive tumor microenvironment (TME) with a profound immune infiltrate populated by a significant number of…”
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19
Hepatitis B virus X (HBX) protein upregulates β-catenin in a human hepatic cell line by sequestering SIRT1 deacetylase
Published in Oncology reports (01-07-2012)“…Hepatitis B virus X (HBX) protein has been reported to induce upregulation of β-catenin, a known proto-oncogene, in p53-knockout and p53-mutant hepatic cell…”
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20
PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase
Published in Experimental & molecular medicine (2011)“…Pancreatic cancer is a notorious disease with a poor prognosis and low survival rates, which is due to limited advances in understanding of the molecular…”
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