Search Results - "KOETHE, JOHN"

Greater Weight Gain in Treatment-naive Persons Starting Dolutegravir-based Antiretroviral Therapy by Bourgi, Kassem, Rebeiro, Peter F, Turner, Megan, Castilho, Jessica L, Hulgan, Todd, Raffanti, Stephen P, Koethe, John R, Sterling, Timothy R

“…Abstract Background Recent studies have reported weight gain in virologically suppressed persons living with human immunodeficiency virus (PLWH) switched from…”
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Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials by Sax, Paul E, Erlandson, Kristine M, Lake, Jordan E, Mccomsey, Grace A, Orkin, Chloe, Esser, Stefan, Brown, Todd T, Rockstroh, Jürgen K, Wei, Xuelian, Carter, Christoph C, Zhong, Lijie, Brainard, Diana M, Melbourne, Kathleen, Das, Moupali, Stellbrink, Hans-Jürgen, Post, Frank A, Waters, Laura, Koethe, John R

“…Abstract Background Initiation of antiretroviral therapy (ART) often leads to weight gain. While some of this weight gain may be an appropriate…”
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Weight Gain in Persons with HIV Switched from Efavirenz-based to Integrase Strand Transfer Inhibitor-based Regimens by Norwood, Jamison, Koethe, John R, Turner, Megan, Bofill, Carmen, Rebeiro, Peter, Shepherd, Bryan, Bebawy, Sally, Hulgan, Todd, Raffanti, Stephen, Haas, David W, Sterling, Timothy R

“…BACKGROUND:With the introduction of integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART), persons living with HIV have a potent new…”
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Risk Factors for Weight Gain Following Switch to Integrase Inhibitor–Based Antiretroviral Therapy by Lake, Jordan E, Wu, Kunling, Bares, Sara H, Debroy, Paula, Godfrey, Catherine, Koethe, John R, McComsey, Grace A, Palella, Frank J, Tassiopoulos, Katherine, Erlandson, Kristine M

“…Abstract Background Treatment initiation with integrase strand transfer inhibitors (INSTIs) has been associated with excess weight gain. Whether similar gains…”
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Adipose Tissue and Immune Function: A Review of Evidence Relevant to HIV Infection by Koethe, John R., Hulgan, Todd, Niswender, Kevin

“…Human immunodeficiency virus type 1 (HIV) infection and antiretroviral therapy (ART) have long been associated with abnormalities in adipose tissue…”
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HIV and antiretroviral therapy-related fat alterations by Koethe, John R., Lagathu, Claire, Lake, Jordan E., Domingo, Pere, Calmy, Alexandra, Falutz, Julian, Brown, Todd T., Capeau, Jacqueline

“…Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss (lipoatrophy), with or without central fat accumulation (lipohypertrophy), was…”
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Obesity and Weight Gain in Persons with HIV by Bailin, Samuel S., Gabriel, Curtis L., Wanjalla, Celestine N., Koethe, John R.

“…Purpose of Review The proportion of overweight and obese persons with HIV (PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to…”
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Weight Gain and Antiretroviral Therapy by Bailin, Samuel S., Koethe, John R.

“…Antiretroviral therapy (ART) agents as a determinant of body weight in ART-naïve and ART-experienced persons with human immunodeficiency virus (HIV) (PWH) has…”
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Effect of the glucagon‐like peptide‐1 receptor agonist liraglutide, compared to caloric restriction, on appetite, dietary intake, body fat distribution and cardiometabolic biomarkers: A randomized trial in adults with obesity and prediabetes by Silver, Heidi J., Olson, Dianna, Mayfield, Dustin, Wright, Patricia, Nian, Hui, Mashayekhi, Mona, Koethe, John R., Niswender, Kevin D., Luther, James M., Brown, Nancy J.

“…Aims To investigate the hypothesis that weight loss with the glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) liraglutide alone would lead to a greater…”
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Obesity and Fat Metabolism in Human Immunodeficiency Virus-Infected Individuals: Immunopathogenic Mechanisms and Clinical Implications by Godfrey, Catherine, Bremer, Andrew, Alba, Diana, Apovian, Caroline, Koethe, John R, Koliwad, Suneil, Lewis, Dorothy, Lo, Janet, McComsey, Grace A, Eckard, Allison, Srinivasa, Suman, Trevillyan, Janine, Palmer, Clovis, Grinspoon, Steven

“…Metabolic complications relating to complex effects of viral and immune-mediated mechanisms are now a focus of clinical care among persons living with human…”
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Weight Change Following Antiretroviral Therapy Switch in People With Viral Suppression: Pooled Data from Randomized Clinical Trials by Erlandson, Kristine M, Carter, Christoph C, Melbourne, Kathleen, Brown, Todd T, Cohen, Cal, Das, Moupali, Esser, Stefan, Huang, Hailin, Koethe, John R, Martin, Hal, McComsey, Grace A, Orkin, Chloe, Post, Frank A, Rockstroh, Jürgen K, Sax, Paul E, Stellbrink, Hans-Jürgen, Waters, Laura, Wei, Xuelian, Lake, Jordan E

“…We sought to identify factors associated with weight gain in randomized clinical trials of antiretroviral therapy (ART) switch. We explored the effects of…”
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Obesity among women with HIV by Millman, Nina, Koethe, John R, Erlandson, Kristine M

“…With the introduction of novel and more potent antiretroviral therapies (ART), persons with HIV (PWH) are living longer lives and experiencing higher rates of…”
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Diabetes in HIV: the Link to Weight Gain by Bailin, Samuel S., Koethe, John R.

“…Purpose of Review The burden of metabolic diseases, including type 2 diabetes mellitus (T2DM), is rising among persons with HIV (PWH) on antiretroviral therapy…”
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Prevalence of low high-density lipoprotein among young adults receiving antiretroviral therapy in Zambia: An opportunity to consider non-communicable diseases in resource-limited settings by Hamooya, Benson M, Musonda, Patrick, Mutale, Wilbroad, Masenga, Sepiso K, Halwiindi, Hikabasa, Mutengo, Katongo H, Chiyeñu, Kaseya O R, Chongwe, Gershom, Koethe, John R, Lipworth, Loren, Heimburger, Douglas C

“…With the introduction of effective antiretroviral therapy (ART), people living with HIV (PLWH) are surviving longer and are at risk for developing metabolic…”
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Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada by Bourgi, Kassem, Jenkins, Cathy A, Rebeiro, Peter F, Palella, Frank, Moore, Richard D, Altoff, Keri N, Gill, John, Rabkin, Charles S, Gange, Stephen J, Horberg, Michael A, Margolick, Joseph, Li, Jun, Wong, Cherise, Willig, Amanda, Lima, Viviane D, Crane, Heidi, Thorne, Jennifer, Silverberg, Michael, Kirk, Gregory, Mathews, William C, Sterling, Timothy R, Lake, Jordan, Koethe, John R

“…Introduction Weight gain following antiretroviral therapy (ART) initiation is common, potentially predisposing some persons with HIV (PWH) to cardio‐metabolic…”
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Inflammation and Metabolic Complications in HIV by Bourgi, Kassem, Wanjalla, Celestine, Koethe, John R.

“…Purpose of Review We aim to provide an in-depth review of recent literature highlighting the role of inflammation involving the adipose tissue, liver, skeletal…”
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From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection by Koethe, John R., Heimburger, Douglas C., PrayGod, George, Filteau, Suzanne

“…The impact of human immunodeficiency virus (HIV) infection on innate and adaptive immune activation occurs in the context of host factors, which serve to…”
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Neurodevelopment: The Impact of Nutrition and Inflammation During Adolescence in Low-Resource Settings by Galler, Janina R, Koethe, John R, Yolken, Robert H

“…Approximately 1 out of 5 children worldwide suffers from childhood malnutrition or stunting and associated health conditions, including an increased…”
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Rising Obesity Prevalence and Weight Gain Among Adults Starting Antiretroviral Therapy in the United States and Canada by Koethe, John R, Jenkins, Cathy A, Lau, Bryan, Shepherd, Bryan E, Justice, Amy C, Tate, Janet P, Buchacz, Kate, Napravnik, Sonia, Mayor, Angel M, Horberg, Michael A, Blashill, Aaron J, Willig, Amanda, Wester, C William, Silverberg, Michael J, Gill, John, Thorne, Jennifer E, Klein, Marina, Eron, Joseph J, Kitahata, Mari M, Sterling, Timothy R, Moore, Richard D

“…The proportion of overweight and obese adults in the United States and Canada has increased over the past decade, but temporal trends in body mass index (BMI)…”
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Antiretrovirals and Weight Change: Weighing the Evidence by Wohl, David Alain, Koethe, John R, Sax, Paul E, McComsey, Grace A, Kuritzkes, Daniel R, Moyle, Graeme, Kaplan, Lee, van Wyk, Jean, Campo, Rafael E, Cohen, Calvin

“…Body weight is influenced by an interplay of individual and environmental factors. In people with HIV (PWH), weight is also influenced by disease status with…”
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