Search Results - "KOESTLER, Josef"

Association between Reactogenicity and Immunogenicity after Vaccination with BNT162b2 by Bauernfeind, Stilla, Salzberger, Bernd, Hitzenbichler, Florian, Scigala, Karolina, Einhauser, Sebastian, Wagner, Ralf, Gessner, André, Koestler, Josef, Peterhoff, David

“…It is not clear whether there is an association between adverse reactions and immune response after vaccination. Seven hundred and thirty-five vaccinees from…”
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Microbiota Disruption Induced by Early Use of Broad Spectrum Antibiotics is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation by Weber, Daniela, Jenq, Robert R, Peled, Jonathan U, Taur, Ying, Hiergeist, Andreas, Koestler, Josef, Dettmer, Katja, Weber, Markus, Wolff, Daniel, Hahn, Joachim, Pamer, Eric G, Herr, Wolfgang, Gessner, André, Oefner, Peter J, van den Brink, Marcel R.M, Holler, Ernst

“…Highlights • Intestinal microbiota play an important role in patients with allogeneic SCT • Early use of antibiotics affects intestinal microbiota composition…”
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Valid gene expression normalization by RT-qPCR in studies on hPDL fibroblasts with focus on orthodontic tooth movement and periodontitis by Kirschneck, Christian, Batschkus, Sarah, Proff, Peter, Köstler, Josef, Spanier, Gerrit, Schröder, Agnes

“…Meaningful, reliable and valid mRNA expression analyses by real-time quantitative PCR (RT-qPCR) can only be achieved, if suitable reference genes are chosen…”
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Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome by Weber, Daniela, Oefner, Peter J., Hiergeist, Andreas, Koestler, Josef, Gessner, André, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja, Holler, Ernst

“…Indole, which is produced from l-tryptophan by commensal bacteria expressing tryptophanase, not only is an important intercellular signal in microbial…”
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Immunity after COVID-19 and vaccination: follow-up study over 1 year among medical personnel by Glück, Vivian, Grobecker, Sonja, Köstler, Josef, Tydykov, Leonid, Bertok, Manuela, Weidlich, Tanja, Gottwald, Christine, Salzberger, Bernd, Wagner, Ralf, Zeman, Florian, Koller, Michael, Gessner, André, Schmidt, Barbara, Glück, Thomas, Peterhoff, David

“…Background The long-term course of immunity among individuals with a history of COVID-19, in particular among those who received a booster vaccination, has not…”
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Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone by Siska, Peter J, Decking, Sonja-Maria, Babl, Nathalie, Matos, Carina, Bruss, Christina, Singer, Katrin, Klitzke, Jana, Schön, Marian, Simeth, Jakob, Köstler, Josef, Siegmund, Heiko, Ugele, Ines, Paulus, Michael, Dietl, Alexander, Kolodova, Kristina, Steines, Louisa, Freitag, Katharina, Peuker, Alice, Schönhammer, Gabriele, Raithel, Johanna, Graf, Bernhard, Geismann, Florian, Lubnow, Matthias, Mack, Matthias, Hau, Peter, Bohr, Christopher, Burkhardt, Ralph, Gessner, Andre, Salzberger, Bernd, Wagner, Ralf, Hanses, Frank, Hitzenbichler, Florian, Heudobler, Daniel, Lüke, Florian, Pukrop, Tobias, Herr, Wolfgang, Wolff, Daniel, Spang, Rainer, Poeck, Hendrik, Hoffmann, Petra, Jantsch, Jonathan, Brochhausen, Christoph, Lunz, Dirk, Rehli, Michael, Kreutz, Marina, Renner, Kathrin

“…Metabolic pathways regulate immune responses and disrupted metabolism leads to immune dysfunction and disease. Coronavirus disease 2019 (COVID-19) is driven by…”
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Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis by Hutchinson, James A., Kronenberg, Katharina, Riquelme, Paloma, Wenzel, Jürgen J., Glehr, Gunther, Schilling, Hannah-Lou, Zeman, Florian, Evert, Katja, Schmiedel, Martin, Mickler, Marion, Drexler, Konstantin, Bitterer, Florian, Cordero, Laura, Beyer, Lukas, Bach, Christian, Koestler, Josef, Burkhardt, Ralph, Schlitt, Hans J., Hellwig, Dirk, Werner, Jens M., Spang, Rainer, Schmidt, Barbara, Geissler, Edward K., Haferkamp, Sebastian

“…Treatment of advanced melanoma with combined PD-1/CTLA-4 blockade commonly causes serious immune-mediated complications. Here, we identify a subset of patients…”
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Computational Design of Epitope-Enriched HIV-1 Gag Antigens with Preserved Structure and Function for Induction of Broad CD8+ T Cell Responses by Asbach, Benedikt, Meier, Johannes P., Pfeifer, Matthias, Köstler, Josef, Wagner, Ralf

“…The partially protective phenotype observed in HIV-infected long-term-non-progressors is often associated with certain HLA alleles, thus indicating that…”
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Detection of carbapenemase-producing Enterobacterales and the BD Phoenix CPO Detect panel by Simon, Michaela, Koestler, Josef, Reischl, Udo, Gessner, André, Jantsch, Jonathan

“…: Treatment options for infections with carbapenem-resistant Enterobacterales are strongly limited. New antimicrobials are not effective against all types of…”
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Liquillizer Does Not Interfere with Galactomannan Antigen Detection in Contrast to Dithiothreitol and N -Acetyl-l-Cysteine by Simon, Michaela, Held, Ingeborg, Teichmann, Lukas, Köstler, Josef, Gessner, André, Schmidt, Barbara, Jantsch, Jonathan

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Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost by Asbach, Benedikt, Kibler, Karen V, Köstler, Josef, Perdiguero, Beatriz, Yates, Nicole L, Stanfield-Oakley, Sherry, Tomaras, Georgia D, Kao, Shing-Fen, Foulds, Kathryn E, Roederer, Mario, Seaman, Michael S, Montefiori, David C, Parks, Robert, Ferrari, Guido, Forthal, Donald N, Phogat, Sanjay, Tartaglia, James, Barnett, Susan W, Self, Steven G, Gottardo, Raphael, Cristillo, Anthony D, Weiss, Deborah E, Galmin, Lindsey, Ding, Song, Heeney, Jonathan L, Esteban, Mariano, Jacobs, Bertram L, Pantaleo, Giuseppe, Wagner, Ralf

“…The use of heterologous immunization regimens and improved vector systems has led to increases in immunogenicity of HIV-1 vaccine candidates in nonhuman…”
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Reduction of aGVHD using chicken antibodies directed against intestinal pathogens in a murine model by Bouazzaoui, Abdellatif, Huber, Elisabeth, Dan, Alexander, Al-Allaf, Faisal A., Pfirstinger, Jochen, Sprotte, Günter, Köstler, Josef, Hiergeist, Andreas, Gessner, Andre, Herr, Wolfgang, Holler, Ernst

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Endotoxins potentiate COX-2 and RANKL expression in compressed PDL cells by Römer, Piero, Köstler, Josef, Koretsi, Vasiliki, Proff, Peter

“…Objective This study aims to demonstrate in vitro the synergistic effect of orthodontic forces and periodontal pathogens on cyclooxygenase-2 regulation and the…”
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IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study by Eidenschink, Lisa, Knoll, Gertrud, Tappe, Dennis, Offner, Robert, Drasch, Thomas, Ehrl, Yvonne, Banas, Bernhard, Banas, Miriam C, Niller, Hans Helmut, Gessner, André, Köstler, Josef, Lampl, Benedikt M J, Pregler, Matthias, Völkl, Melanie, Kunkel, Jürgen, Neumann, Bernhard, Angstwurm, Klemens, Schmidt, Barbara, Bauswein, Markus

“…More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern…”
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Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease by Holler, Ernst, Butzhammer, Peter, Schmid, Karin, Hundsrucker, Christian, Koestler, Josef, Peter, Katrin, Zhu, Wentao, Sporrer, Daniela, Hehlgans, Thomas, Kreutz, Marina, Holler, Barbara, Wolff, Daniel, Edinger, Matthias, Andreesen, Reinhard, Levine, John E, Ferrara, James L, Gessner, Andre, Spang, Rainer, Oefner, Peter J

“…Abstract Next-generation sequencing of the hypervariable V3 region of the 16s rRNA gene isolated from serial stool specimens collected from 31 patients…”
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Omicron’s binding to sotrovimab, casirivimab, imdevimab, CR3022, and sera from previously infected or vaccinated individuals by Mader, Anna-Lena, Tydykov, Leonid, Glück, Vivian, Bertok, Manuela, Weidlich, Tanja, Gottwald, Christine, Stefl, Alexa, Vogel, Matthias, Plentz, Annelie, Köstler, Josef, Salzberger, Bernd, Wenzel, Jürgen J., Niller, Hans Helmut, Jantsch, Jonathan, Wagner, Ralf, Schmidt, Barbara, Glück, Thomas, Gessner, André, Peterhoff, David

“…SARS-CoV-2 Omicron is the first pandemic variant of concern exhibiting an abrupt accumulation of mutations particularly in the receptor-binding domain that is…”
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Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype by Harari, Alexandre, Cellerai, Cristina, Enders, Felicitas Bellutti, Köstler, Josef, Codarri, Laura, Tapia, Gonzalo, Boyman, Onur, Castro, Erika, Gaudieri, Silvana, James, Ian, John, Mina, Wagner, Ralf, Mallal, Simon, Pantaleo, Giuseppe

“…We studied CD8 T cell responses against HIV-1, cytomegalovirus, Epstein-Barr virus, and influenza in 128 subjects and demonstrate that polyfunctional CD8 T…”
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Effects of mechanical strain on periodontal ligament fibroblasts in presence of Aggregatibacter actinomycetemcomitans lysate by Schröder, Agnes, Stumpf, Julia, Paddenberg, Eva, Neubert, Patrick, Schatz, Valentin, Köstler, Josef, Jantsch, Jonathan, Deschner, James, Proff, Peter, Kirschneck, Christian

“…Many adult orthodontic patients suffer from periodontitis, which is caused by oral pathogens such as the gram-negative Aggregatibacter actinomycetemcomitans…”
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Validation of T-Track® CMV to assess the functionality of cytomegalovirus-reactive cell-mediated immunity in hemodialysis patients by Banas, Bernhard, Böger, Carsten A, Lückhoff, Gerhard, Krüger, Bernd, Barabas, Sascha, Batzilla, Julia, Schemmerer, Mathias, Köstler, Josef, Bendfeldt, Hanna, Rascle, Anne, Wagner, Ralf, Deml, Ludwig, Leicht, Joachim, Krämer, Bernhard K

“…Uncontrolled cytomegalovirus (CMV) replication in immunocompromised solid-organ transplant recipients is a clinically relevant issue and an indication of…”
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Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens by Asbach, Benedikt, Kliche, Alexander, Köstler, Josef, Perdiguero, Beatriz, Esteban, Mariano, Jacobs, Bertram L, Montefiori, David C, LaBranche, Celia C, Yates, Nicole L, Tomaras, Georgia D, Ferrari, Guido, Foulds, Kathryn E, Roederer, Mario, Landucci, Gary, Forthal, Donald N, Seaman, Michael S, Hawkins, Natalie, Self, Steven G, Sato, Alicia, Gottardo, Raphael, Phogat, Sanjay, Tartaglia, James, Barnett, Susan W, Burke, Brian, Cristillo, Anthony D, Weiss, Deborah E, Francis, Jesse, Galmin, Lindsey, Ding, Song, Heeney, Jonathan L, Pantaleo, Giuseppe, Wagner, Ralf

“…In a follow-up to the modest efficacy observed in the RV144 trial, researchers in the HIV vaccine field seek to substantiate and extend the results by…”
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