Search Results - "KODO, Kazuki"

MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells by Ong, Sang-Ging, Lee, Won Hee, Kodo, Kazuki, Wu, Joseph C.

“…MicroRNAs (miRNAs) are key components of a broadly conserved post-transcriptional mechanism that controls gene expression by targeting mRNAs. miRNAs regulate…”
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A Japanese Boy with Dysmorphic Syndrome with Multiple Pituitary Hormone Deficiency and Gingival Fibromatosis Due to a Pathogenic KCNQ1 Variant by Nakajima, Hisakazu, Kodo, Kazuki, Morimoto, Hidechika, Hori, Shinsuke, Sugimoto, Satoru

“…A six-year-old boy presented with short stature and gingival fibromatosis (GF). Dysmorphic features included slant optic fissures, a high-arched palate, thick…”
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Modeling Inherited Cardiac Disorders: A Cell Is Worth a Thousand Genes by Sallam, Karim, Kodo, Kazuki, Wu, Joseph C.

“…Advances in the understanding and treatment of cardiac disorders have been thwarted by the inability to study beating human cardiac cells in vitro. Induced…”
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Echocardiographic Left Ventricular Z-Score Utility in Predicting Pulmonary-Systemic Flow Ratio in Children With Ventricular Septal Defect or Patent Ductus Arteriosus by Sumitomo, Naofumi F., Kodo, Kazuki, Maeda, Jun, Miura, Masaru, Yamagishi, Hiroyuki

“…Background:The correlation between the Z-score of the left ventricular (LV) diameter and the LV volume-overload due to pulmonary over-circulation in children…”
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HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore by Ong, Sang-Ging, Lee, Won Hee, Theodorou, Louise, Kodo, Kazuki, Lim, Shiang Y, Shukla, Deepa H, Briston, Thomas, Kiriakidis, Serafim, Ashcroft, Margaret, Davidson, Sean M, Maxwell, Patrick H, Yellon, Derek M, Hausenloy, Derek J

“…Hypoxia-inducible factor-1 (HIF-1) has been reported to promote tolerance against acute myocardial ischaemia-reperfusion injury (IRI). However, the mechanism…”
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GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling by Kodo, Kazuki, Nishizawa, Tsutomu, Furutani, Michiko, Arai, Shoichi, Yamamura, Eiji, Joo, Kunitaka, Takahashi, Takao, Matsuoka, Rumiko, Yamagishi, Hiroyuki

“…Congenital heart diseases (CHD) occur in nearly 1% of all live births and are the major cause of infant mortality and morbidity. Although an improved…”
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Angiotensin 1-7 stimulates brown adipose tissue and reduces diet-induced obesity by Morimoto, Hidechika, Mori, Jun, Nakajima, Hisakazu, Kawabe, Yasuhiro, Tsuma, Yusuke, Fukuhara, Shota, Kodo, Kazuki, Ikoma, Kazuya, Matoba, Satoaki, Oudit, Gavin Y, Hosoi, Hajime

“…The renin-angiotensin system is a key regulator of metabolism with beneficial effects of the angiotensin 1-7 (Ang 1-7) peptide. We hypothesized that the…”
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Successful and unsuccessful management for indolent Kawasaki disease by Kikuoka, Izumi, Yamamoto, Kazuki, Kodo, Kazuki, Maeda, Jun, Yamagishi, Hiroyuki

“…1,2 Therefore, it is necessary to pay attention to additional treatment for afebrile cases, which are not mentioned in the Guidelines on Acute Stage Kawasaki…”
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Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction by Ong, Sang-Ging, Huber, Bruno C, Lee, Won Hee, Kodo, Kazuki, Ebert, Antje D, Ma, Yu, Nguyen, Patricia K, Diecke, Sebastian, Chen, Wen-Yi, Wu, Joseph C

“…Human induced pluripotent stem cells (iPSCs) are attractive candidates for therapeutic use, with the potential to replace deficient cells and to improve…”
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Genetic and Cellular Interaction During Cardiovascular Development Implicated in Congenital Heart Diseases by Kodo, Kazuki, Uchida, Keiko, Yamagishi, Hiroyuki

“…Congenital heart disease (CHD) is the most common life-threatening congenital anomaly. CHD occurs due to defects in cardiovascular development, and the…”
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Polysplenia Syndrome as a Risk Factor for Early Progression of Pulmonary Hypertension by Shibata, Akimichi, Mori, Hiroki, Kodo, Kazuki, Nakanishi, Toshio, Yamagishi, Hiroyuki

“…Background: Recent progress in surgical and intensive care has improved the prognosis of congenital heart disease (CHD) associated with heterotaxy syndrome…”
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Comparison of Non‐Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell‐ versus Induced Pluripotent Stem Cell‐Derived Cardiomyocytes by Lee, Won Hee, Chen, Wen‐Yi, Shao, Ning‐Yi, Xiao, Dan, Qin, Xulei, Baker, Natalie, Bae, Hye Ryeong, Wei, Tzu‐Tang, Wang, Yongjun, Shukla, Praveen, Wu, Haodi, Kodo, Kazuki, Ong, Sang‐Ging, Wu, Joseph C.

“…Both human embryonic stem cell‐derived cardiomyocytes (ESC‐CMs) and human induced pluripotent stem cell‐derived CMs (iPSC‐CMs) can serve as unlimited cell…”
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Type 2 inositol 1,4,5-trisphosphate receptor inhibits the progression of pulmonary arterial hypertension via calcium signaling and apoptosis by Shibata, Akimichi, Uchida, Keiko, Kodo, Kazuki, Miyauchi, Takayuki, Mikoshiba, Katsuhiko, Takahashi, Takao, Yamagishi, Hiroyuki

“…Pulmonary arterial hypertension (PAH) is a progressive disease associated with vasoconstriction and remodeling. Intracellular Ca 2+ signaling regulates the…”
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Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice by Kodo, Kazuki, Sugimoto, Satoru, Nakajima, Hisakazu, Mori, Jun, Itoh, Ikuyo, Fukuhara, Shota, Shigehara, Keiichi, Nishikawa, Taichiro, Kosaka, Kitaro, Hosoi, Hajime

“…Erythropoietin (EPO), clinically used as a hematopoietic drug, has received much attention due to its nonhematopoietic effects. EPO reportedly has beneficial…”
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Successful Preoperative Partial Splenic Artery and Aneurysm Embolization for Thrombocytopenia Associated with Failed Fontan Circulation by Sumitomo, Naofumi F, Tamura, Masashi, Asano, Satoshi, Yuasa, Erika, Oyanagi, Takayuki, Inoue, Masanori, Kodo, Kazuki, Yamagishi, Hiroyuki

“…Long-term complications after the Fontan procedure are important concerns for patients with pediatric and adult congenital heart disease. Although…”
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Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development by Kodo, Kazuki, Shibata, Shinsuke, Miyagawa-Tomita, Sachiko, Ong, Sang-Ging, Takahashi, Hiroshi, Kume, Tsutomu, Okano, Hideyuki, Matsuoka, Rumiko, Yamagishi, Hiroyuki

“…The cardiac neural crest cells (cNCCs) and the second heart field (SHF) play key roles in development of the cardiac outflow tract (OFT) for establishment of…”
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Erythropoietin and long-acting erythropoiesis stimulating agent ameliorate non-alcoholic fatty liver disease by increasing lipolysis and decreasing lipogenesis via EPOR/STAT pathway by Tsuma, Yusuke, Mori, Jun, Ota, Takeshi, Kawabe, Yasuhiro, Morimoto, Hidechika, Fukuhara, Shota, Kodo, Kazuki, Umemura, Atsushi, Nakajima, Hisakazu, Hosoi, Hajime

“…Erythropoietin (EPO) has been reported to exert a beneficial effect on glucose metabolism in obesity. However, the effect of EPO on lipid metabolism and…”
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Case Report: COVID-19 Pandemic Exacerbates Eating Disorder by Social and Intrafamilial Isolation by Katsumi, Yoshiki, Kodo, Kazuki, Goto, Sachiko

“…The coronavirus disease-2019 (COVID-19) pandemic has increased the stress levels of children and their parents and diagnoses of eating disorders (EDs),…”
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High-fat diet accelerates extreme obesity with hyperphagia in female heterozygous Mecp2-null mice by Fukuhara, Shota, Nakajima, Hisakazu, Sugimoto, Satoru, Kodo, Kazuki, Shigehara, Keiichi, Morimoto, Hidechika, Tsuma, Yusuke, Moroto, Masaharu, Mori, Jun, Kosaka, Kitaro, Morimoto, Masafumi, Hosoi, Hajime

“…Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutation of the methyl-CpG-binding protein 2 (MECP2) gene. Although RTT has been…”
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A 3-year-old boy with congenital absence of the portal vein presenting fasting hypoglycemia and postprandial hyperglycemia with hyperinsulinemia by Nakajima, Hisakazu, Kodo, Kazuki

“…A 3-year-old boy developed hypoglycemia with convulsions, rectal bleeding and hyperammonemia. Three-dimensional computed tomography scanning revealed the…”
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