Search Results - "KOCKX, M. M"
-
1
Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression
Published in Breast cancer research : BCR (18-02-2019)“…Inflammatory breast cancer (IBC) is a rare and rapidly progressive form of invasive breast cancer. The aim of this study was to explore the clinical evolution,…”
Get full text
Journal Article -
2
Phagocytosis of Apoptotic Cells by Macrophages Is Impaired in Atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2005)“…OBJECTIVE—Apoptotic cell death has been demonstrated in advanced human atherosclerotic plaques. Apoptotic cells (ACs) should be rapidly removed by macrophages,…”
Get full text
Journal Article -
3
Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma
Published in Modern pathology (01-10-2014)“…Uveal melanoma is a lethal cancer with a strong propensity to metastasize. Limited therapeutic options are available once the disease has disseminated. A…”
Get full text
Journal Article -
4
Apoptosis in atherosclerosis: beneficial or detrimental?
Published in Cardiovascular research (01-02-2000)“…Several groups have demonstrated apoptotic cell death in atherosclerotic plaques. The significance of apoptosis in atherosclerosis depends on the stage of the…”
Get full text
Journal Article -
5
Optimal Evaluation of Programmed Death Ligand-1 on Tumor Cells Versus Immune Cells Requires Different Detection Methods
Published in Archives of pathology & laboratory medicine (1976) (01-08-2018)“…- The benefit of programmed death ligand-1 (PD-L1) immunohistochemistry (IHC) as a method to select patients who may benefit from programmed death receptor-1…”
Get full text
Journal Article -
6
Apoptosis in the Atherosclerotic Plaque: Quantitative and Qualitative Aspects
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-1998)“…Several laboratories have demonstrated the presence of apoptotic cell death in atherosclerotic plaques. Apoptosis occurs in at least 2 stages. The final…”
Get full text
Journal Article -
7
Development and Validation of a Histological Method to Measure Microvessel Density in Whole-Slide Images of Cancer Tissue
Published in PloS one (01-09-2016)“…Despite all efforts made to develop predictive biomarkers for antiangiogenic therapies, no unambiguous markers have been identified so far. This is due to…”
Get full text
Journal Article -
8
Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy
Published in Journal of the American College of Cardiology (13-02-2007)“…Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy Stefan Verheye, Wim Martinet, Mark M. Kockx, Michiel W. M. Knaapen, Koen Salu,…”
Get full text
Journal Article -
9
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques
Published in Circulation (New York, N.Y.) (20-08-2002)“…The formation of reactive oxygen species is a critical event in atherosclerosis because it promotes cell proliferation, hypertrophy, growth arrest, and/or…”
Get full text
Journal Article -
10
Reactive oxygen species induce RNA damage in human atherosclerosis
Published in European journal of clinical investigation (01-05-2004)“…Background Reactive oxygen species (ROS)‐induced DNA damage has recently been identified in both human and experimental atherosclerosis. This study was…”
Get full text
Journal Article -
11
Apoptosis and related proteins in different stages of human atherosclerotic plaques
Published in Circulation (New York, N.Y.) (16-06-1998)“…The transition of a fatty streak into an atherosclerotic plaque is characterized by the appearance of focal and diffuse regions of cell death. We have…”
Get full text
Journal Article -
12
Apoptotic versus autophagic cell death in heart failure
Published in Cardiovascular research (01-08-2001)“…Progressive loss of cardiomyocytes is one of the most important pathogenic characteristics of heart failure. Apoptosis may be an important mode of cell death…”
Get full text
Journal Article -
13
Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms
Published in American journal of physiology. Heart and circulatory physiology (01-04-2006)“…Circulating stem cells home within the myocardium, probably as the first step of a tissue regeneration process. This step requires adhesion to cardiac…”
Get more information
Journal Article -
14
EGFR fluorescence in situ hybridisation assay: guidelines for application to non-small-cell lung cancer
Published in Journal of clinical pathology (01-11-2009)“…There is a need for predictive biomarkers that identify non-small-cell lung cancer (NSCLC) patients most likely to respond to epidermal growth factor receptor…”
Get more information
Journal Article -
15
7-Ketocholesterol Induces Protein Ubiquitination, Myelin Figure Formation, and Light Chain 3 Processing in Vascular Smooth Muscle Cells
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2004)“…OBJECTIVE—Oxysterols such as 7-ketocholesterol (7-KC) are important mediators of cell death in atherosclerosis. Therefore, in vitro studies of human smooth…”
Get full text
Journal Article -
16
Rapid Detection of Enterovirus RNA in Cerebrospinal Fluid Specimens with a Novel Single-Tube Real-Time Reverse Transcription-PCR Assay
Published in Journal of Clinical Microbiology (01-11-2001)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
17
Oxidative DNA Damage and Repair in Experimental Atherosclerosis Are Reversed by Dietary Lipid Lowering
Published in Circulation research (13-04-2001)“…Increased oxidative stress is a major characteristic of hypercholesterolemia-induced atherosclerosis. The oxidative environment is mainly created by the…”
Get full text
Journal Article -
18
In Situ Detection of Starvation-induced Autophagy
Published in The journal of histochemistry and cytochemistry (01-01-2006)“…Autophagy is a regulated bulk degradation process involved in many different human pathologies. Transmission electron microscopy (TEM) is currently the only…”
Get full text
Journal Article -
19
The spatial relations among immune cells are prognostic in inflammatory breast cancer
Published in Annals of oncology (01-05-2019)Get full text
Journal Article -
20
Targeted Next Generation Sequencing reveals previously unidentified TSC1 and TSC2 mutations
Published in BMC medical genetics (25-02-2015)“…Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in TSC1 and TSC2. Conventional DNA diagnostic screens identify a TSC1 or…”
Get full text
Journal Article