Search Results - "KOCKUM, I."

Inflammation-related plasma and CSF biomarkers for multiple sclerosis by Huang, Jesse, Khademia, Mohsen, Fugger, Lars, Lindhe, Örjan, Novakova, Lenka, Axelsson, Markus, Malmeström, Clas, Constantinescu, Clara, Lycke, Jan, Piehl, Fredrik, Olsson, Tomas, Kockum, Ingrid

“…Effective biomarkers for multiple sclerosis diagnosis, assessment of prognosis, and treatment responses, in particular those measurable in blood, are largely…”
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Skewness of Temperature Data Implies an Abrupt Change in the Climate System Between 1985 and 1991 by Skelton, A., Kirchner, N., Kockum, I.

“…Instrumental records of mean annual temperature extend back to the seventeenth and eighteenth centuries at multiple sites in Europe. For such long time series,…”
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Plasma neurofilament light levels are associated with risk of disability in multiple sclerosis by Manouchehrinia, Ali, Stridh, Pernilla, Khademi, Mohsen, Leppert, David, Barro, Christian, Michalak, Zuzanna, Benkert, Pascal, Lycke, Jan, Alfredsson, Lars, Kappos, Ludwig, Piehl, Fredrik, Olsson, Tomas, Kuhle, Jens, Kockum, Ingrid

“…OBJECTIVETo investigate the association between plasma neurofilament light chain (pNfL) levels and the risk of developing sustained disability worsening…”
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Stressful life events are associated with the risk of multiple sclerosis by Jiang, X., Olsson, T., Hillert, J., Kockum, I., Alfredsson, L.

“…Background and purpose Unexpected stressful life events may alter immune function and affect susceptibility to autoimmune diseases including multiple sclerosis…”
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Changes in groundwater chemistry before two consecutive earthquakes in Iceland by Skelton, Alasdair, Andrén, Margareta, Kristmannsdóttir, Hrefna, Stockmann, Gabrielle, Mörth, Carl-Magnus, Sveinbjörnsdóttir, Árny, Jónsson, Sigurjón, Sturkell, Erik, Guðrúnardóttir, Helga Rakel, Hjartarson, Hreinn, Siegmund, Heike, Kockum, Ingrid

“…Precursor events to earthquakes are rarely reproduced. Measurement of groundwater chemistry in Iceland between 2008 and 2013 reveals distinct changes prior to…”
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Epstein–Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis by Biström, M., Jons, D., Engdahl, E., Gustafsson, R., Huang, J., Brenner, N., Butt, J., Alonso‐Magdalena, L., Gunnarsson, M., Vrethem, M., Bender, N., Waterboer, T., Granåsen, G., Olsson, T., Kockum, I., Andersen, O., Fogdell‐Hahn, A., Sundström, Peter

“…Background and purpose Infections with human herpesvirus 6A (HHV‐6A) and Epstein–Barr virus (EBV) have been linked to multiple sclerosis (MS) development. For…”
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Comparative effectiveness of natalizumab on cognition in multiple sclerosis: A cohort study by Manouchehrinia, Ali, Larsson, Hanna, Karim, Mohammad Ehsanul, Lycke, Jan, Olsson, Tomas, Kockum, Ingrid

“…Background: Cognitive impairment occurs in 40%–70% of persons with multiple sclerosis (MS). Objective: To examine the effectiveness of natalizumab compared…”
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Rapid discontinuation of baclofen as a treatment for spasticity among MS patients with incident and prevalent diagnoses by Smith, K. A., Piehl, F., Olsson, T., Alfredsson, L., Hillert, J., Kockum, I., Stridh, P., Montgomery, Scott

“…Introduction : Baclofen is the first line drug choice for spasticity; a common MS feature influencing function and quality of life. Its prescription and…”
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Epstein-Barr virus and multiple sclerosis: interaction with HLA by Sundqvist, E, Sundström, P, Lindén, M, Hedström, A K, Aloisi, F, Hillert, J, Kockum, I, Alfredsson, L, Olsson, T

“…Epstein-Barr virus (EBV) infection, history of infectious mononucleosis (IM) and HLA-A and DRB1 have all been proposed as risk factors for multiple sclerosis…”
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Cytomegalovirus seropositivity is negatively associated with multiple sclerosis by Sundqvist, E, Bergström, T, Daialhosein, H, Nyström, M, Sundström, P, Hillert, J, Alfredsson, L, Kockum, I, Olsson, T

“…Background: Epidemiological data suggest a role for common viruses in the pathogenesis of multiple sclerosis (MS), and recent data showed a negative…”
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Cytomegalovirus seropositivity is associated with reduced risk of multiple sclerosis—a presymptomatic case–control study by Grut, Viktor, Biström, Martin, Salzer, Jonatan, Stridh, Pernilla, Jons, Daniel, Gustafsson, Rasmus, Fogdell‐Hahn, Anna, Huang, Jesse, Brenner, Nicole, Butt, Julia, Bender, Noemi, Lindam, Anna, Alonso‐Magdalena, Lucia, Gunnarsson, Martin, Vrethem, Magnus, Bergström, Tomas, Andersen, Oluf, Kockum, Ingrid, Waterboer, Tim, Olsson, Tomas, Sundström, Peter

“…Background and purpose Epstein–Barr virus (EBV) and human herpesvirus 6A (HHV‐6A) are associated with increased risk of multiple sclerosis (MS). Conversely,…”
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Sunlight is associated with decreased multiple sclerosis risk: no interaction with human leukocyte antigen-DRB115 by Bäärnhielm, M., Hedström, A. K., Kockum, I., Sundqvist, E., Gustafsson, S. A., Hillert, J., Olsson, T., Alfredsson, L.

“…Background:  Both insufficient exposure to sunlight and vitamin D deficiency have been associated with an increased risk for multiple sclerosis (MS). An…”
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The impact of hybrid immunity on immune responses after SARS‐CoV‐2 vaccination in persons with multiple sclerosis treated with disease‐modifying therapies by Rabenstein, Monika, Thomas, Olivia G., Carlin, Giorgia, Khademi, Mohsen, Högelin, Klara Asplund, Malmeström, Clas, Axelsson, Markus, Brandt, Anne Frandsen, Gafvelin, Guro, Grönlund, Hans, Kockum, Ingrid, Piehl, Fredrik, Lycke, Jan, Olsson, Tomas, Hessa, Tara

“…Background and purpose Hybrid immunity to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) develops from a combination of natural infection and…”
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Smoking and alcohol associated to the risk of developing Myasthenia gravis in a Swedish nationwide prevalent cohort by Petersson, M., Jons, D., Feresiadou, A., Ilinca, A., Lundin, F., Johansson, R., Budzianowska, A., Roos, A., Kågström, V., Gunnarsson, Martin, Sundström, P., Klareskog, L., Olsson, T., Kockum, I., Piehl, F., Alfredsson, L., Brauner, S.

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Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity by Ineichen, B. V., Moridi, T., Ewing, E., Ouellette, R., Manouchehrinia, A., Stawiarz, L., Ferreira, D., Muehlboeck, S. J., Kuhle, J., Westman, E., Leppert, D., Hillert, J., Olsson, T., Kockum, I., Piehl, F., Granberg, T.

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Increase in Epstein Barr virus serologies precedes neuroaxonal damage in pre-symptomatic multiple sclerosis by Jons, D., Bergström, T., Zetterberg, H., Biström, M., Alonso-Magdalena, L., Gunnarsson, Martin, Vrethem, M., Blennow, K., Nilsson, S., Huang, J., Kockum, I., Olsson, T., Waterboer, T., Sundström, P., Andersen, O.

“…Introduction : Epstein-Barr virus (EBV) infection may be a pre-condition  for  the development  of  multiple  sclerosis  (MS).  EBV  antibodies, predominantly…”
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HLA-DRB1alleles and symptoms associated with Heerfordt's syndrome in sarcoidosis by Darlington, P, Tallstedt, L, Padyukov, L, Kockum, I, Cederlund, K, Eklund, A, Grunewald, J

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Technological readiness and implementation of genomic‐driven precision medicine for complex diseases by Franks, P. W., Melén, E., Friedman, M., Sundström, J., Kockum, I., Klareskog, L., Almqvist, C., Bergen, S. E., Czene, K., Hägg, S., Hall, P., Johnell, K., Malarstig, A., Catrina, A., Hagström, H., Benson, M., Gustav Smith, J., Gomez, M. F, Orho‐Melander, M., Jacobsson, B., Halfvarson, J., Repsilber, D., Oresic, M., Jern, C., Melin, B., Ohlsson, C., Fall, T., Rönnblom, L., Wadelius, M., Nordmark, G., Johansson, Å., Rosenquist, R., Sullivan, P. F.

“…The fields of human genetics and genomics have generated considerable knowledge about the mechanistic basis of many diseases. Genomic approaches to diagnosis,…”
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Humoral and cellular immune responses after SARSCoV-2-Vaccination in a Swedish cohort of persons with multiple sclerosis treated with disease modifying therapies by Rabenstein, M., Thomas, O. G., Carlin, G., Hellström, Cecilia, Nilsson, Peter, Khademi, M., Hogelin, K. Asplund, Lycke, J., Malmestrom, C., Axelsson, M., Brandt, A. Frandsen, Gafvelin, G., Gronlund, H., Kockum, I., Piehl, F., Olsson, T., Hessa, T.

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Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden by Carlsson, A, Kockum, I, Lindblad, B, Engleson, L, Nilsson, A, Forsander, G, Karlsson, A-K, Kernell, A, Ludvigsson, J, Marcus, C, Zachrisson, I, Ivarsson, S-A, Lernmark, Å

“…Objective: Type 1 diabetes and obesity has increased in childhood. We therefore tested the hypothesis that type 1 diabetes human leukocyte antigen DQ (HLA-DQ)…”
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