Search Results - "KO, Kinarm"

Generation of integration-free human induced pluripotent stem cells from a patient with sporadic Parkinson’s disease by Lee, Yukyeong, Jeong, Dahee, Ham, Seokbeom, Son, Jaeseung, Ko, Kinarm

“…A human induced pluripotent stem cell (iPSC) line (KKUi002-A) was generated from a skin fibroblast of a 57-years-old (at sampling) male patient diagnosed with…”
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Oct4-Induced Pluripotency in Adult Neural Stem Cells by Kim, Jeong Beom, Sebastiano, Vittorio, Wu, Guangming, Araúzo-Bravo, Marcos J., Sasse, Philipp, Gentile, Luca, Ko, Kinarm, Ruau, David, Ehrich, Mathias, van den Boom, Dirk, Meyer, Johann, Hübner, Karin, Bernemann, Christof, Ortmeier, Claudia, Zenke, Martin, Fleischmann, Bernd K., Zaehres, Holm, Schöler, Hans R.

“…The four transcription factors Oct4, Sox2, Klf4, and c-Myc can induce pluripotency in mouse and human fibroblasts. We previously described direct reprogramming…”
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Epiblast Stem Cell Subpopulations Represent Mouse Embryos of Distinct Pregastrulation Stages by Han, Dong Wook, Tapia, Natalia, Joo, Jin Young, Greber, Boris, Araúzo-Bravo, Marcos J., Bernemann, Christof, Ko, Kinarm, Wu, Guangming, Stehling, Martin, Do, Jeong Tae, Schöler, Hans R.

“…Embryonic stem cells (ESCs) comprise at least two populations of cells with divergent states of pluripotency. Here, we show that epiblast stem cells (EpiSCs)…”
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Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Proteome Quantitation of Mouse Embryonic Stem Cells to a Depth of 5,111 Proteins by Graumann, Johannes, Hubner, Nina C., Kim, Jeong Beom, Ko, Kinarm, Moser, Markus, Kumar, Chanchal, Cox, Jürgen, Schöler, Hans, Mann, Matthias

“…Embryonic stem (ES) cells are pluripotent cells isolated from mammalian preimplantation embryos. They are capable of differentiating into all cell types and…”
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CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2 by Yu, Kyung-Rok, Yang, Se-Ran, Jung, Ji-Won, Kim, Hyongbum, Ko, Kinarm, Han, Dong Wook, Park, Sang-Bum, Choi, Soon Won, Kang, Soo-Kyung, Schöler, Hans, Kang, Kyung-Sun

“…CD49f (integrin subunit α6) regulates signaling pathways in a variety of cellular activities. However, the role of CD49f in regulating the differentiation and…”
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Induction of Pluripotency in Adult Unipotent Germline Stem Cells by Ko, Kinarm, Tapia, Natalia, Wu, Guangming, Kim, Jeong Beom, Bravo, Marcos J. Araúzo, Sasse, Philipp, Glaser, Tamara, Ruau, David, Han, Dong Wook, Greber, Boris, Hausdörfer, Kirsten, Sebastiano, Vittorio, Stehling, Martin, Fleischmann, Bernd K., Brüstle, Oliver, Zenke, Martin, Schöler, Hans R.

“…Mouse and human stem cells with features similar to those of embryonic stem cells have been derived from testicular cells. Although pluripotent stem cells have…”
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Therapeutic Potential of Induced Neural Stem Cells for Spinal Cord Injury by Hong, Jin Young, Lee, Sung Ho, Lee, Seung Chan, Kim, Jong-Wan, Kim, Kee-Pyo, Kim, Sung Min, Tapia, Natalia, Lim, Kyung Tae, Kim, Jonghun, Ahn, Hong-Sun, Ko, Kinarm, Shin, Chan Young, Lee, Hoon Taek, Schöler, Hans R., Hyun, Jung Keun, Han, Dong Wook

“…The spinal cord does not spontaneously regenerate, and treatment that ensures functional recovery after spinal cord injury (SCI) is still not available…”
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Distinct Developmental Ground States of Epiblast Stem Cell Lines Determine Different Pluripotency Features by Bernemann, Christof, Greber, Boris, Ko, Kinarm, Sterneckert, Jared, Han, Dong Wook, Araúzo‐Bravo, Marcos J., Schöler, Hans R.

“…Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from mouse postimplantation embryos at embryonic day (E) 5.5–E7.5 at the onset of gastrulation,…”
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The role of microRNA-325-3p as a critical player in cell death in NSCs and astrocytes by Lee, Yukyeong, Lee, Seung-Won, Jeong, Dahee, Lee, Hye Jeong, Ko, Kinarm

“…Neural stem cells (NSCs) are defined by their ability to self-renew and generate various cell types within the nervous system. Understanding the underlying…”
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Effect of an Endoplasmic Reticulum Retention Signal Tagged to Human Anti-Rabies mAb SO57 on Its Expression in Arabidopsis and Plant Growth by Song, Ilchan, Lee, Young Koung, Kim, Jin Wook, Lee, Seung-Won, Park, Se Ra, Lee, Hae Kyung, Oh, Soyeon, Ko, Kinarm, Kim, Mi Kyung, Park, Soon Ju, Kim, Dae Heon, Kim, Moon-Soo, Kim, Do Sun, Ko, Kisung

“…Transgenic expressing an anti-rabies monoclonal antibody (mAb), SO57, was obtained using -mediated floral dip transformation. The endoplasmic reticulum (ER)…”
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Multigenerational effect of maternal bisphenol A exposure on DNA methylation in F1 sperm by Jeong, Dahee, Ham, Seokbeom, Lee, Minseong, Lee, Hye Jeong, Choi, Na Young, Lee, Seung-Won, Ko, Kinarm

“…Backgrounds Bisphenol A (BPA), an environmental contaminant, is known as an endocrine disruptor and has developmental, reproductive, and epigenetic toxicity…”
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Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming by Lim, Kyung Tae, Lee, Seung Chan, Gao, Yimeng, Kim, Kee-Pyo, Song, Guangqi, An, Su Yeon, Adachi, Kenjiro, Jang, Yu Jin, Kim, Jonghun, Oh, Kyoung-Jin, Kwak, Tae Hwan, Hwang, Seon In, You, Jueng Soo, Ko, Kinarm, Koo, Seung-Hoi, Sharma, Amar Deep, Kim, Jong-Hoon, Hui, Lijian, Cantz, Tobias, Schöler, Hans R., Han, Dong Wook

“…Recent studies have shown that defined factors could lead to the direct conversion of fibroblasts into induced hepatocyte-like cells (iHeps). However, reported…”
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Establishment of an integration-free human induced pluripotent stem cell line (TJCi001-A) from normal bone marrow-derived mesenchymal stem cells by Choi, Na Young, Lee, YuRa, Park, Yo Seph, Ko, Kinarm, Park, BoonSaeng, Koh, Yong-Gon

“…Bone marrow-derived mesenchymal stem cells (BM-MSCs) possess excellent therapeutic potential for the treatment of various diseases including graft-versus-host…”
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A Plant-Derived Antigen-Antibody Complex Induces Anti-Cancer Immune Responses by Forming a Large Quaternary Structure by Kim, Deuk-Su, Kang, Yang Joo, Lee, Kyung Jin, Qiao, Lu, Ko, Kinarm, Kim, Dae Heon, Myeung, Soon Chul, Ko, Kisung

“…The antigen-antibody complex (AAC) has novel functions for immunomodulation, encouraging the application of diverse quaternary protein structures for…”
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Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody by Lee, Jeong-Hwan, Park, Da-Young, Lee, Kyung-Jin, Kim, Young-Kwan, So, Yang-Kang, Ryu, Jae-Sung, Oh, Seung-Han, Han, Yeon-Soo, Ko, Kinarm, Choo, Young-Kug, Park, Sung-Joo, Brodzik, Robert, Lee, Kyoung-Ki, Oh, Doo-Byoung, Hwang, Kyung-A, Koprowski, Hilary, Lee, Yong Seong, Ko, Kisung

“…Plant genetic engineering, which has led to the production of plant-derived monoclonal antibodies (mAb(P)s), provides a safe and economically effective…”
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Coadministration of endothelial and smooth muscle cells derived from human induced pluripotent stem cells as a therapy for critical limb ischemia by Park, Jin Ju, Kwon, Yang Woo, Kim, Jeong Won, Park, Gyu Tae, Yoon, Jung Won, Kim, Ye Seul, Kim, Da Sol, Kwon, Sang Mo, Bae, Sun Sik, Ko, Kinarm, Kim, Chang‐Seok, Kim, Jae Ho

“…Critical limb ischemia is a condition in which tissue necrosis occurs due to arterial occlusion, resulting in limb amputation in severe cases. Both endothelial…”
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Generation of human androgenetic induced pluripotent stem cells by Choi, Na Young, Bang, Jin Seok, Park, Yo Seph, Lee, Minseong, Hwang, Han Sung, Ko, Kisung, Myung, Soon Chul, Tapia, Natalia, Schöler, Hans R., Kim, Gwang Jun, Ko, Kinarm

“…In humans, parthenogenesis and androgenesis occur naturally in mature cystic ovarian teratomas and androgenetic complete hydatidiform moles (CHM),…”
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Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant by Kim, Kibum, Kang, Yang Joo, Park, Se Ra, Kim, Do-Sun, Lee, Seung-Won, Ko, Kinarm, Ponndorf, Daniel, Ko, Kisung

“…Immunization with thetumor-associated antigen GA733 glycoprotein, which is highly expressed in colorectal cancer, is considered to be a promising strategy for…”
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Enhancement of proliferation of human umbilical cord blood–derived CD34+ hematopoietic stem cells by a combination of hyper-interleukin-6 and small molecules by Park, Yo Seph, Lee, Yukyeong, Choi, Na Young, Hwang, Han Sung, Rose-John, Stefan, Zenke, Martin, Ko, Kinarm

“…Umbilical cord blood (UCB) is an alternative source of allogeneic hematopoietic stem cells (HSCs) for transplantation to treat various hematological disorders…”
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Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system by Lee, Minseong, Choi, Na Young, Park, Soree, Bang, Jin Seok, Lee, Yukyeong, Jeong, Dahee, Ham, Seokbeom, Lim, Sohee, Kim, Kyun-Hwan, Ko, Kinarm

“…OCT4 and NANOG are core transcription factor genes in self-renewal, differentiation, and reprogramming. Here, we generated an OCT4-EGFP, NANOG-tdTomato dual…”
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