Search Results - "KNORR, Maike"
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Lysozyme M―Positive Monocytes Mediate Angiotensin II―Induced Arterial Hypertension and Vascular Dysfunction
Published in Circulation (New York, N.Y.) (20-09-2011)“…Angiotensin II (ATII), a potent vasoconstrictor, causes hypertension, promotes infiltration of myelomonocytic cells into the vessel wall, and stimulates both…”
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Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction
Published in Journal of the American Heart Association (01-09-2016)“…Background The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure…”
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Interleukin 17 Drives Vascular Inflammation, Endothelial Dysfunction, and Arterial Hypertension in Psoriasis-Like Skin Disease
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2014)“…OBJECTIVE—Interleukin (IL)-17A is regarded as an important cytokine to drive psoriasis, an inflammatory skin disease marked by increased cardiovascular…”
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Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1-driven fibrotic remodeling in ischemic heart failure
Published in The Journal of clinical investigation (15-02-2023)“…Despite major advances in acute interventions for myocardial infarction (MI), adverse cardiac remodeling and excess fibrosis after MI causing ischemic heart…”
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Airborne disease: a case of a Takotsubo cardiomyopathie as a consequence of nighttime aircraft noise exposure
Published in European heart journal (01-10-2016)Get full text
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A sequential interferon gamma directed chemotactic cellular immune response determines survival and cardiac function post-myocardial infarction
Published in Cardiovascular research (01-11-2019)“…Abstract Aims Myelomonocytic cells are critical in injury and healing post-myocardial infarction (MI). Mechanisms of regulation, however, are incompletely…”
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Inflammatory Monocytes Determine Endothelial Nitric-oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II
Published in The Journal of biological chemistry (03-10-2014)“…Endothelial nitric-oxide synthase (eNOS) uncoupling and increased inducible NOS (iNOS) activity amplify vascular oxidative stress. The role of inflammatory…”
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Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension
Published in Science translational medicine (01-02-2017)“…Multicellular interactions of platelets, leukocytes, and the blood vessel wall support coagulation and precipitate arterial and venous thrombosis. High levels…”
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Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1—evidence for direct and indirect antioxidant actions of bilirubin
Published in Journal of molecular and cellular cardiology (01-08-2010)“…Abstract Heme oxygenase-1 (HO-1) is highly protective in various pathophysiological states such as cardiovascular and neurodegenerative diseases. HO-1-derived…”
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Interplay of NK cells and monocytes in vascular inflammation and myocardial infarction
Published in Frontiers in physiology (14-08-2014)“…Inflammatory monocytes and macrophages have been identified as key players in the pathogenesis of atherosclerosis, arterial hypertension, and myocardial…”
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Randomised, non-inferiority, controlled procedural outcomes TrIal comParing reverse T And Protrusion versus double-kissing and crush stenting: protocol of the TIP TAP I randomised trial
Published in BMJ open (16-06-2020)“…IntroductionTo assess the impact of ‘reverse T and Protrusion’ (TAP) technique on the outcome after stenting of true bifurcation lesions of the left main (LM)…”
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Late-Onset Prosthetic Endocarditis with Paraaortic Abscess Caused by Cutibacterium acnes
Published in Infectious disease reports (01-10-2023)“…Cutibacterium acnes, an integral component of the skin’s customary bacterial flora, represents a Gram-positive anaerobic bacterium characterized by its low…”
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Six-months clinical and intracoronary imaging follow-up after reverse T and protrusion or double-kissing and crush stenting for the treatment of complex left main bifurcation lesions
Published in Frontiers in cardiovascular medicine (27-04-2023)“…There is a debate regarding the best stent strategy for unprotected distal left main (LM) bifurcation disease. Among two-stent techniques, double-kissing and…”
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Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice
Published in Biology open (01-01-2019)“…The prototypic protein disulfide isomerase (PDI), encoded by the gene, has been described as a survival factor in ischemic cardiomyopathy. However, the role of…”
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Use of intravascular ultrasound for optimal vessel sizing in chronic total occlusion percutaneous coronary intervention
Published in Frontiers in cardiovascular medicine (03-08-2022)“…Aim The aim of this study is to provide evidence on how use of standardized intravascular ultrasound (IVUS) use impacts stent size choice in the setting of…”
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Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl peptidase-4 inhibition
Published in Cardiovascular research (01-10-2012)Get full text
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Regulation of Human Mitochondrial Aldehyde Dehydrogenase (ALDH-2) Activity by Electrophiles in Vitro
Published in The Journal of biological chemistry (18-03-2011)“…Recently, mitochondrial aldehyde dehydrogenase (ALDH-2) was reported to reduce ischemic damage in an experimental myocardial infarction model. ALDH-2 activity…”
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Vascular dysfunction in streptozotocin-induced experimental diabetes strictly depends on insulin deficiency
Published in Journal of vascular research (01-01-2011)“…In previous studies we and others have shown that streptozotocin (STZ)-induced diabetes in rats is associated with vascular oxidative stress and dysfunction…”
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Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation
Published in Journal of the American College of Cardiology (14-07-2015)“…Abstract Background Heme oxygenase-1 (HO-1) is an inducible stress-responsive enzyme converting heme to bilirubin, carbon monoxide, and free iron, which exerts…”
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