Search Results - "KNIGHT, Kristin R"

Platinum-Induced Ototoxicity in Children: A Consensus Review on Mechanisms, Predisposition, and Protection, Including a New International Society of Pediatric Oncology Boston Ototoxicity Scale by BROCK, Penelope R, KNIGHT, Kristin R, SULLIVAN, Michael, NEUWELT, Edward A, FREYER, David R, CAMPBELL, Kathleen C. M, STEYGER, Peter S, BLAKLEY, Brian W, RASSEKH, Shahrad R, CHANG, Kay W, FLIGOR, Brian J, RAJPUT, Kaukab

“…The platinum chemotherapy agents cisplatin and carboplatin are widely used in the treatment of adult and pediatric cancers. Cisplatin causes hearing loss in at…”
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Group-Wide, Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy (ACCL05C1): A Report From the Children's Oncology Group by Knight, Kristin R, Chen, Lu, Freyer, David, Aplenc, Richard, Bancroft, Mary, Bliss, Bonnie, Dang, Ha, Gillmeister, Biljana, Hendershot, Eleanor, Kraemer, Dale F, Lindenfeld, Lanie, Meza, Jane, Neuwelt, Edward A, Pollock, Brad H, Sung, Lillian

“…Purpose Optimal assessment methods and criteria for reporting hearing outcomes in children who receive treatment with cisplatin are uncertain. The objectives…”
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Ototoxicity in Children Receiving Platinum Chemotherapy: Underestimating a Commonly Occurring Toxicity That May Influence Academic and Social Development by GILMER KNIGHT, Kristin R, KRAEMER, Dale F, NEUWELT, Edward A

“…To describe the frequency and severity of ototoxicity in a series of pediatric patients treated with platinum-based chemotherapy. Serial audiologic evaluations…”
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Reevaluation of sodium thiosulfate otoprotection using the consensus International Society of Paediatric Oncology Ototoxicity Scale: A report from the Children's Oncology Group study ACCL0431 by Orgel, Etan, Knight, Kristin R., Villaluna, Doojduen, Krailo, Mark, Esbenshade, Adam J., Sung, Lillian, Freyer, David R.

“…In two randomized trials (Children's Oncology Group ACCL0431 and International Childhood Liver Tumour Strategy Group SIOPEL‐6), sodium thiosulfate (STS)…”
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Early Changes in Auditory Function As a Result of Platinum Chemotherapy: Use of Extended High-Frequency Audiometry and Evoked Distortion Product Otoacoustic Emissions by KNIGHT, Kristin R, KRAEMER, Dale F, WINTER, Christiane, NEUWELT, Edward A

“…The objective is to describe progressive changes in hearing and cochlear function in children and adolescents treated with platinum-based chemotherapy and to…”
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Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial by Orgel, Etan, Knight, Kristin R, Chi, Yueh-Yun, Malvar, Jemily, Rushing, Teresa, Mena, Victoria, Eisenberg, Laurie S, Rassekh, Shahrad R, Ross, Colin J D, Scott, Erika N, Neely, Michael, Neuwelt, Edward A, Muldoon, Leslie L, Freyer, David R

“…Cisplatin-induced hearing loss (CIHL) is common and permanent. As compared with earlier otoprotectants, we hypothesized N-acetylcysteine (NAC) offers potential…”
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Prevalence and risk factors for cisplatin-induced hearing loss in children, adolescents, and young adults: a multi-institutional North American cohort study by Moke, Diana J, Luo, Chunqiao, Millstein, Joshua, Knight, Kristin R, Rassekh, Shahrad R, Brooks, Beth, Ross, Colin J D, Wright, Michael, Mena, Victoria, Rushing, Teresa, Esbenshade, Adam J, Carleton, Bruce C, Orgel, Etan

“…Cisplatin is used to treat a wide range of childhood cancers and cisplatin-induced hearing loss (CIHL) is a common and debilitating toxicity. We aimed to…”
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Evaluation and Management of Hearing Loss in Survivors of Childhood and Adolescent Cancers: A Report From the Children's Oncology Group by Bass, Johnnie K., Knight, Kristin R., Yock, Torunn I., Chang, Kay W., Cipkala, Douglas, Grewal, Satkiran S.

“…Hearing loss (HL) is common in childhood cancer survivors exposed to platinum chemotherapy and/or cranial radiation and can severely impact quality of life…”
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Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report by Meijer, Annelot J M, van den Heuvel-Eibrink, Marry M, Brooks, Beth, Am Zehnhoff-Dinnesen, Antoinette G, Knight, Kristin R, Freyer, David R, Chang, Kay W, Hero, Barbara, Papadakis, Vassilios, Frazier, A Lindsay, Blattmann, Claudia, Windsor, Rachael, Morland, Bruce, Bouffet, Eric, Rutkowski, Stefan, Tytgat, Godelieve A M, Geller, James I, Hunter, Lisa L, Sung, Lillian, Calaminus, Gabriele, Carleton, Bruce C, Helleman, Hiske W, Foster, Jennifer H, Kruger, Mariana, Cohn, Richard J, Landier, Wendy, van Grotel, Martine, Brock, Penelope R, Hoetink, Alexander E, Rajput, Kaukab M

“…Ototoxicity is an irreversible direct and late effect of certain childhood cancer treatments. Audiologic surveillance during therapy as part of the supportive…”
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Intraarterial chemotherapy and osmotic blood‐brain barrier disruption for patients with embryonal and germ cell tumors of the central nervous system by Jahnke, Kristoph, Kraemer, Dale F., Knight, Kristin R., Fortin, David, Bell, Susan, Doolittle, Nancy D., Muldoon, Leslie L., Neuwelt, Edward A.

“…BACKGROUND. The rate of durable responses in embryonal and certain germ cell tumors of the central nervous system (CNS) is unsatisfactory. Intraarterial…”
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INTRAVENOUS N-ACETYLCYSTEINE TO PREVENT CISPLATIN-INDUCED HEARING LOSS IN CHILDREN: A NONRANDOMIZED CONTROLLED PHASE 1 TRIAL by Orgel, Etan, Knight, Kristin R., Chi, Yueh-Yun, Malvar, Jemily, Rushing, Teresa, Mena, Victoria, Eisenberg, Laurie S., Rassekh, Shahrad R., Ross, Colin JD, Scott, Erika N., Neely, Michael, Neuwelt, Edward A., Muldoon, Leslie L., Freyer, David R

“…Cisplatin-induced hearing loss (CIHL) results from oxidant-mediated damage to the cochlea. Sodium thiosulfate (STS) successfully reduced CIHL in recently…”
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