Search Results - "KLUGHERZ, Bruce D"

Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model by SUZUKI, Takeshi, KOPIA, Greg, YEUNG, Alan C, TIO, Fermin, TSAO, Philip S, FALOTICO, Robert, CARTER, Andrew J, HAYASHI, Shin-Ichiro, BAILEY, Lynn R, LLANOS, Gerard, WILENSKY, Robert, KLUGHERZ, Bruce D, PAPANDREOU, George, NARAYAN, Pallassana, LEON, Martin B

“…The purpose of this study was to determine the efficacy of stent-based delivery of sirolimus (SRL) alone or in combination with dexamethasone (DEX) to reduce…”
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Gene delivery from a DNA controlled-release stent in porcine coronary arteries by Levy, Robert J, Klugherz, Bruce D, Jones, Peter L, Cui, Xiumin, Chen, Weiliam, Meneveau, Nicolas F, DeFelice, Suzanne, Connolly, Jeanne, Wilensky, Robert L

“…Expandable intra-arterial stents are widely used for treating coronary disease. We hypothesized that local gene delivery could be achieved with the controlled…”
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Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent by Klugherz, Bruce D, Llanos, Gerard, Lieuallen, Warren, Kopia, Gregory A, Papandreou, George, Narayan, Pallassana, Sasseen, Brett, Adelman, Steven J, Falotico, Robert, Wilensky, Robert L

“…BACKGROUNDIn-stent restenosis is caused by neointimal hyperplasia. Sirolimus (rapamycin; Wyeth Research, Radnor, Pennsylvania, USA) inhibits vascular smooth…”
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Spontaneous Coronary Artery Dissection: A Case Series of 9 Patients With Literature Review by Ghani, Ali Raza, Inayat, Faisal, Ali, Nouman Safdar, Anjum, Reema, Viray, Michael, Hashmi, Arsalan Talib, Riaz, Iqra, Klugherz, Bruce D., Virk, Hafeez Ul Hassan

“…Spontaneous coronary artery dissection is an increasingly recognized nonatherosclerotic cause of acute coronary syndrome. Reports regarding the prognosis and…”
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Relation of percutaneous coronary intervention of complex lesions to clinical outcomes (from the NHLBI Dynamic Registry) by Wilensky, Robert L, Selzer, Faith, Johnston, Janet, Laskey, Warren K, Klugherz, Bruce D, Block, Peter, Cohen, Howard, Detre, Katherine, Williams, David O

“…Advances in percutaneous coronary intervention (PCI) have reduced complications but expanded indications. We used the National Heart, Lung, and Blood Insitute…”
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Hemodynamic Effects of Sildenafil in Men with Severe Coronary Artery Disease by Herrmann, Howard C, Chang, Gene, Klugherz, Bruce D, Mahoney, Paul D

“…Erectile dysfunction affects up to 30 million men in the United States 1 and may be particularly common in patients with heart disease, because of the presence…”
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Tetralogy of Fallot: The Oldest Reported Survivor of Brock's Procedure by Manchikalapudi, Rama Bindu, Klugherz, Bruce D.

“…We report the case of a 79‐y‐old male with Tetralogy of Fallot (TOF) who underwent Brock's procedure in his twenties and has survived event‐free. Brock's…”
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Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus by Klugherz, Bruce D, Song, Cunxian, DeFelice, Suzanne, Cui, Xiumin, Lu, Zhiban, Connolly, Jeanne, Hinson, J Travis, Wilensky, Robert L, Levy, Robert J

“…Deployment of coronary stents to relieve atherosclerotic obstruction has benefitted millions of patients. However, gene therapy to prevent in-stent restenosis,…”
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One-year clinical outcomes of protected and unprotected left main coronary artery stenting by Kelley, Michael P., Klugherz, Bruce D., Hashemi, Seyed M., Meneveau, Nicolas F., Johnston, Janet M., Matthai, William H., Banka, Vidya S., Herrmann, Howard C., Hirshfeld, John W., Kimmel, Stephen E., Kolansky, Daniel M., Horwitz, Phillip A., Schiele, Francois, Bassand, Jean-Pierre L., Wilensky, Robert L.

“…Aims To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA…”
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Comparison of degree of platelet inhibition by abciximab versus tirofiban in patients with unstable angina pectoris and non–Q-wave myocardial infarction undergoing percutaneous coronary intervention by Herrmann, Howard C., Swierkosz, Tomasz A., Kapoor, Shiv, Tardiff, Danielle C., DiBattiste, Peter M., Hirshfeld, John W., Klugherz, Bruce D., Kolansky, Daniel M., Magness, Kathleen, Valettas, Nicholas, Wilensky, Robert L.

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Reduced vascular complications after percutaneous coronary interventions with a nonmechanical suture device: Results from the randomized RACE study by Sanborn, Timothy A., Ogilby, J. David, Ritter, James M., Stone, Gregg W., Klugherz, Bruce D., Fields, Ronald H., White, Christopher C., Wilensky, Robert L.

“…The objective of this study was to evaluate the safety and efficacy of a novel nonmechanical percutaneous suture device, X‐Press, after diagnostic…”
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Three-year clinical follow-up after Palmaz-Schatz stenting by Klugherz, Bruce D., DeAngelo, Debra L., Kim, Back K., Herrmann, Howard C., Hirshfeld, John W., Kolansky, Daniel M.

“…Our goals were to examine late clinical outcome in a cohort of patients who electively received Palmaz-Schatz intracoronary stents, to identify specific…”
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Percutaneous coronary intervention of complex lesions is associated with increased in-hospital and one-year adverse event rates: results from the NHLBI dynamic registry by Wilensky, Robert L., Johnston, Janet, Selzer, Faith, Klugherz, Bruce D., Laskey, Warre K., Block, Peter, Cohen, Howard, Detre, Katherine, Williams, David O.

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Prediction rule for insignificant coronary artery disease in patients being considered for elective coronary angiography by Samaha, Frederick F., Klugherz, Bruce D., Wilensky, Robert L., Localio, A.Russel, Williams, Monica, Kimmel, Stephen E.

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Adenovirus-catheter compatibility determines gene expression following delivery to porcine myocardium by Nalmark, Wendy A., Klugherz, Bruce D., Lepore, John J., Guy, Sloane, Moainie, Sina, Gorman, Robert, Palasis, Maria, Wilensky, Robert L.

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Adenovirus-catheter compatibility increases gene expression after delivery to porcine myocardium by Naimark, Wendy A, Lepore, John J, Klugherz, Bruce D, Wang, Zihua, Guy, T Sloane, Osman, Hashim, Moainie, Sina L, Gorman, Robert C, Reed, Guy, Gorman, 3rd, Joseph H, Palasis, Maria, Parmacek, Michael S, Wilensky, Robert L

“…Endomyocardial injection of adenoviral gene vectors enables localized delivery to comprised myocardial tissue. However, many materials used in endomyocardial…”
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One-year outcomes of unprotected and protected left main stenting in the current era by Kelley, Michael P., Klugherz, Bruce D., Hashemi, Sayed M., Meneveau, Nicolas F., Johnston, Janet M., Matthai, William H., Banka, Vidya S., Herrmann, Howard C., Hirshfeld, John W., Kolansky, Daniel M., Horwitz, Phillip A., Schiele, Francois, Bassand, Jean-Pierre L., Wilensky, Robert L.

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Predictors of clinical outcome following percutaneous intervention for in-stent restenosis by Klugherz, Bruce D., Meneveau, Nicolas F., Kolansky, Daniel M., Herrmann, Howard C., Schiele, François, Matthai, William H., Groh, William C., Untereker, William J., Hirshfeld, John W., Bassand, Jean-Pierre L., Wilensky, Robert L.

“…Percutaneous intervention for the first episode of in-stent restenosis was performed in 177 patients 5.4 ± 0.3 months after native coronary stent implantation…”
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Separate and combined effects of local and continuous intravenous administration of beta-cyclodextrin tetradecasulfate on intimal hyperplasia after angioplasty in porcine coronary arteries by Meneveau, Nicolas F, Klugherz, Bruce D, Chaquor, Brahim, Golden, Michael A, Jouille, Madeleine M, Macarek, Edward, Weisz, Paul B, Wilensky, Robert L

“…Beta-Cyclodextrin tetradecasulfate binds fibroblast growth factors and possesses anticoagulant properties. This study was designed to assess the separate and…”
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β-Cyclodextrin tetradecasulfate, a novel cyclic oligosaccharide, inhibits thrombus and neointimal formation after coronary vascular injury by Meneveau, Nicolas F, Klugherz, Bruce D, Chaqour, Brahim, Anand, Vibha, Tomaszewski, John E, Joullié, Madeleine M, Macarak, Edward, Golden, Michael, Weisz, Paul B, Wilensky, Robert L

“…BACKGROUNDNeointimal formation is a major cause of restenosis after interventional vascular procedures. β-Cyclodextrin tetradecasulfate (β-CDT) has been shown…”
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