Search Results - "KLOTZ, U."

Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem by Klotz, U

“…Proton pump inhibitors (e.g. omeprazole/esomeprazole, lansoprazole, pantoprazole, rabeprazole) have a prominent role in the short- and long-term management of…”
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Colonic targeting of aminosalicylates for the treatment of ulcerative colitis by Klotz, U.

“…Aminosalicylates (5-aminosalicylic acid) represent drugs of first choice in the treatment of ulcerative colitis. Two different therapeutic approaches have been…”
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Topical delivery of therapeutic agents in the treatment of inflammatory bowel disease by Klotz, Ulrich, Schwab, Matthias

“…For targeting local and systemic inflammatory processes in inflammatory bowel disease (IBD) therapeutic agents of first choice (e.g. aminosalicylates,…”
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Ziconotide--a novel neuron-specific calcium channel blocker for the intrathecal treatment of severe chronic pain--a short review by Klotz, U

“…Worldwide a large number of patients suffer from severe chronic pain even after treatment with opioids following the 3-step analgesic ladder developed by the…”
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Diffusion bonding of gamma-TiAl using modified Ti/Al nanolayers by Duarte, L.I., Viana, F., Ramos, A.S., Vieira, M.T., Leinenbach, C., Klotz, U.E., Vieira, M.F.

“…► Ti/Al multilayers are promising interlayers for getting joins between titanium aluminides. ► When Ti/Al multilayers are doped with Ag or Cu it is observed a…”
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Interface formation in infiltrated Al(Si)/diamond composites by Beffort, O., Khalid, F.A., Weber, L., Ruch, P., Klotz, U.E., Meier, S., Kleiner, S.

“…This study pertains to the investigation of interface formation in infiltrated Al-based composites with high-volume fractions of monocrystalline synthetic…”
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Influence of crystallinity on thermo-process ability and mechanical properties in a Au-based bulk metallic glass by Cardinal, S., Pelletier, J.M., Eisenbart, M., Klotz, U.E.

“…The present investigation addresses the impact of crystallinity on the mechanical properties: hardness (HV) and toughness (KIC) in an…”
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Critical evaluation of the Fe–Ni, Fe–Ti and Fe–Ni–Ti alloy systems by Cacciamani, G., De Keyzer, J., Ferro, R., Klotz, U.E., Lacaze, J., Wollants, P.

“…The Fe–Ni–Ti alloy system has been evaluated, together with Fe–Ni and Fe–Ti binary subsystems, to provide reliable information for applications and in view of…”
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Experimental study of the Fe–Ni–Ti system by Duarte, L.I., Klotz, U.E., Leinenbach, C., Palm, M., Stein, F., Löffler, J.F.

“…In this investigation phase relations in the Fe–Ni–Ti system were studied and two isothermal sections at 800 °C and 1000 °C as well as a revised liquidus…”
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The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2′- O-methyl-RNA directed against telomerase in lung cancer cells by Taetz, S., Nafee, N., Beisner, J., Piotrowska, K., Baldes, C., Mürdter, T.E., Huwer, H., Schneider, M., Schaefer, U.F., Klotz, U., Lehr, C.-M.

“…Tailorable cationic chitosan/PLGA nanoparticles (CPNP) were used for the delivery of an antisense 2′- O-methyl-RNA (2OMR) directed against RNA template of…”
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The role of aminosalicylates at the beginning of the new millennium in the treatment of chronic inflammatory bowel disease by KLOTZ, U

“…To discuss the pharmacological properties of aminosalicylates and their potential value in the treatment of chronic inflammatory bowel disease (IBD). A review…”
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Nanocrystalline phases and epitaxial interface reactions during brazing of diamond grits with silver based Incusil-ABA alloy by Klotz, U.E., Khalid, F.A., Elsener, H.-R.

“…The commercial active brazing alloy “Incusil-ABA” was used for the bonding of diamond grits in order to assess their suitability for high performance machining…”
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Effects of aminosalicylates on thiopurine S‐methyltransferase activity: an ex vivo study in patients with inflammatory bowel disease by Xin, H., Fischer, C., Schwab, M., Klotz, U.

“…Summary Background : Based on in vitro experiments using recombinant human thiopurine S‐methyltransferase this enzyme is inhibited by sulfasalazine…”
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On the interfacial nanostructure of brazed diamond grits by Khalid, F.A, Klotz, U.E, Elsener, H.-R, Zigerlig, B, Gasser, P

“…The interfacial structure, phases and carbides have been examined in a brazing filler metal with embedded diamond grits. Brazing of superhard and superabrasive…”
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Investigation of mechanical, corrosion and optical properties of an 18 carat Au–Cu–Si–Ag–Pd bulk metallic glass by Mozgovoy, S., Heinrich, J., Klotz, U.E., Busch, R.

“…The following article shows that amorphous gold based alloys are a promising material for jewelry applications. Specimens in form of amorphous plates were…”
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Hepatic expression of galectin-3 and receptor for advanced glycation end products in patients with liver disease by Butscheid, M, Hauptvogel, P, Fritz, P, Klotz, U, Alscher, D M

“…Background: Advanced glycation end products (AGEs) are a heterogeneous group of glycosylated proteins (of which carboxymethyl-lysine (CML) is the most common)…”
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Data integration for identification of important transcription factors of STAT6-mediated cell fate decisions by Jargosch, M, Kröger, S, Gralinska, E, Klotz, U, Fang, Z, Chen, W, Leser, U, Selbig, J, Groth, D, Baumgrass, R

“…Data integration has become a useful strategy for uncovering new insights into complex biological networks. We studied whether this approach can help to…”
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Reassessment of the benefit/risk-ratio of selective COX-2-inhibitors by Klotz, U

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Influence of diet and nutritional status on drug metabolism by WALTER-SACK, I, KLOTZ, U

“…Genetic and environmental factors contribute to a wide inter- and intraindividual variability in drug metabolism. Among the environmental factors that may…”
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Biopharmaceutical characterization of the telomerase inhibitor BRACO19 by TAETZ, S, BALDES, C, KLOTZ, U, LEHR, C.-M, MÜRDTER, T. E, KLEIDEITER, E, PIOTROWSKA, K, BOCK, U, HALTNER-UKOMADU, E, MUELLER, J, HUWER, H, SCHAEFER, U. F

“…To characterize the telomerase inhibitor and G-quadruplex stabilizing substance 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis (3-pyrrolodino-propionamido)…”
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