Search Results - "KLING, P. J"

Maternal pregnancy weight gain and cord blood iron status are associated with eosinophilia in infancy by Weigert, R, Dosch, N C, Bacsik-Campbell, M E, Guilbert, T W, Coe, C L, Kling, P J

“…Objective: Allergic disease is multifactorial in origin. Because iron nutrition affects immune responses and maternal pregnancy weight gain impairs fetal iron…”
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Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists by Evans, B. E, Rittle, K. E, Bock, M. G, DiPardo, R. M, Freidinger, R. M, Whitter, W. L, Lundell, G. F, Veber, D. F, Anderson, P. S, Chang, R. S. L, Lotti, V. J, Cerino, D. J, Chen, T. B, Kling, P. J, Kunkel, K. A, Springer, J. P, Hirshfield, J

“…3-(Acylamino)-5-phenyl-2H-1,4-benzodiazepines, antagonists of the peptide hormone cholecystokinin (CCK), are described. Developed by reasoned modification of…”
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Neonatal iron status is impaired by maternal obesity and excessive weight gain during pregnancy by Phillips, A K, Roy, S C, Lundberg, R, Guilbert, T W, Auger, A P, Blohowiak, S E, Coe, C L, Kling, P J

“…Objective: Maternal iron needs increase sixfold during pregnancy, but obesity interferes with iron absorption. We hypothesized that maternal obesity impairs…”
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Serum erythropoietin levels during infancy: Associations with erythropoiesis by Kling, Pamela J., Schmidt, Robert L., Roberts, Robin A., Widness, John A.

“…OBJECTIVE: To determine plasma erythropoietin levels and their association with hemoglobin and reticulocyte counts in healthy term infants. DESIGN: We compared…”
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Roles of erythropoietin in human milk by Kling, PJ

“…Erythropoietin (Epo) is one of many biologically active growth factors present in human and animal milk. Accumulating evidence shows important developmental…”
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Human milk as a potential enteral source of erythropoietin by KLING, P. J, SULLIVAN, T. M, ROBERTS, R. A, PHILIPPS, A. F, KOLDOVSKY, O

“…In addition to its content of traditional nutrients, milk is a rich source of hormones and peptides, which survive digestion in the neonatal gastrointestinal…”
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Plasma transferrin receptor levels and indices of erythropoiesis and iron status in healthy term infants by KLING, P. J, ROBERTS, R. A, WIDNESS, J. A

“…The goal of this study was to determine if the postnatal changes in plasma transferrin receptor (TfR) levels in healthy infants were associated with changes in…”
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Elevated zinc protoporphyrin heme ratios in umbilical cord blood after diabetic pregnancy by Lesser, K B, Schoel, S B, Kling, P J

“…Offspring of diabetes patients may suffer from tissue iron deficiency. Erythrocyte zinc protoporphyrin/heme (ZnPP/H) ratios measure impaired iron status. The…”
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Iron deprivation increases erythropoietin production in vitro, in normal subjects and patients with malignancy by Kling, P J, Dragsten, P R, Roberts, R A, Dos Santos, B, Brooks, D J, Hedlund, B E, Taetle, R

“…Although tissue hypoxia is the major stimulus for erythropoietin (EPO) production, serum EPO (sEPO) levels at any given Hb in iron-deficiency anaemia are…”
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Congenital cutaneous candidiasis: case report and review by Raval, D S, Barton, L L, Hansen, R C, Kling, P J

“…This report describes a preterm infant with congenital cutaneous candidiasis associated with paronychia, dystrophy of the nail plates, and marked, transient…”
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Iron-deficient erythropoiesis in premature infants measured by blood zinc protoporphyrin/heme by Winzerling, Joy J., Kling, Pamela J.

“…We measured red blood cell zinc protoporphyrin/heme (ZnPP/H) ratios in premature infants at hospital discharge. ZnPP/heme ratios correlated directly with red…”
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Pharmacokinetics and pharmacodynamics of erythropoietin during therapy in an infant with renal failure by Kling, P J, Widness, J A, Guillery, E N, Veng-Pedersen, P, Peters, C, DeAlarcon, P A

“…We treated an infant with anemia and chronic renal failure with recombinant human erythropoietin (300 to 750 U/kg subcutaneously per week) and iron (6 mg/kg…”
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Analgesic activity of diflunisal [MK-647; 5-(2,4-difluorophenyl)salicylic acid] in rats with hyperalgesia induced by Freund's adjuvant by Winter, C A, Kling, P J, Tocco, D J, Tanabe, K

“…A method is described for testing analgesia for narcotic or nonnarcotic drugs in rats injected with Freund's adjuvant in the tail, by manipulation of the tail…”
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Absorption of Milk‐Borne Insulin‐Like Growth Factor‐I Into Portal Blood of Suckling Rats by Philipps, Anthony F., Dvořák, Bohuslav, Kling, Pamela J., Grille, James G., Koldovský, Otakar

“…ABSTRACT Background Insulin‐like growth factors (IGFs) are potent mitogens that have been implicated in control of growth and development during the perinatal…”
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Enteral absorption of erythropoietin in the suckling rat by MILLER-GILBERT, Amy L, DUBUQUE, Suzanne H, DVORAK, Bohuslav, WILLIAMS, Catherine S, GRILLE, James G, WOODWARD, Suann S, KOLDOVSKY, Otakar, KLING, Pamela J

“…Milk contains biologically relevant concentrations of erythropoietin (Epo), the primary hormone responsible for erythrocyte production. In animals, milk-borne…”
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Evidence that cholecystokinin octapeptide (CCK-8) acts as a potent, full agonist on gastrin receptors for acid secretion in the isolated mouse stomach: lack of antagonism by the specific CCK antagonist asperlicin by Lotti, V J, Chang, R S, Kling, P J, Cerino, D J

“…Cholecystokinin octapeptide (CCK-8) (EC50 = 5 nM) was considerably more potent than pentagastrin (EC50 = 161 nM) in stimulating acid secretion in the isolated…”
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Score for neonatal acute physiology and phlebotomy blood loss predict erythrocyte transfusions in premature infants by Kling, P J, Sullivan, T M, Leftwich, M E, Roe, D J

“…To test the hypothesis that utilization of a previously described measure of acuity (ie, the score for neonatal acute physiology [SNAP]) during the first 7…”
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In vitro pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for AT2 receptors by CHANG, R. S. L, LOTTI, V. J, MANTLO, N. B, TSING-BAU CHEN, O'MALLEY, S. S, BENDESKY, R. J, KLING, P. J, KIVLIGHN, S. D, SIEGL, P. K. S, ONDEYKA, D, GREENLEE, W. J

“…L-163,017 (6-[benzoylamino]-7-methyl-2-propyl-3-[[2'-(N-(3-methyl-1-butoxy) carbonylaminosulfonyl) [1,1']-biphenyl-4-yl]methyl]-3H-imidazo[4,5-b]pyridine)…”
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A faculty-house staff retreat by Kling, P J, Fost, N C

“…There has been much discussion regarding the causes of stress in residency training programs and solutions to alleviate the pressure. As a partial solution, we…”
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A new simple mouse model for the in vivo evaluation of cholecystokinin (CCK) antagonists: comparative potencies and durations of action of nonpeptide antagonists by Lotti, V J, Cerino, D J, Kling, P J, Change, R S

“…A new simple mouse assay for the in vivo evaluation of CCK antagonists which is based upon visual determination of the gastric emptying of a charcoal meal is…”
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