Search Results - "KLESCHYOV, A. L"

Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH‐2−/− mice by Wenzel, P, Hink, U, Oelze, M, Seeling, A, Isse, T, Bruns, K, Steinhoff, L, Brandt, M, Kleschyov, A L, Schulz, E, Lange, K, Weiner, H, Lehmann, J, Lackner, K J, Kawamoto, T, Münzel, T, Daiber, A

“…Background and purpose: Mitochondrial aldehyde dehydrogenase (ALDH‐2) has been shown to provide a pathway for bioactivation of organic nitrates and to be prone…”
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Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock by STOCLET, J. C, MARTINEZ, M. C, OHLMANN, P, CHASSEROT, S, SCHOTT, C, KLESCHYOV, A. L, SCHNEIDER, F, ANDRIANTSITOHAINA, R

“…The role of endogenous nitric oxide (NO) and cyclooxygenase metabolites was investigated in contractile responses of small omental arteries from patients with…”
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Nitric oxide production and endothelium‐dependent vasorelaxation induced by wine polyphenols in rat aorta by Andriambeloson, Emile, Kleschyov, Andrei L, Muller, Bernard, Beretz, Alain, Stoclet, Jean Claude, Andriantsitohaina, Ramaroson

“…The aim of this work was to investigate the mechanism of vasorelaxation induced by red wine polyphenolic compounds (RWPC) and two defined polyphenols contained…”
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Evidence for N‐acetylcysteine‐sensitive nitric oxide storage as dinitrosyl‐iron complexes in lipopolysaccharide‐treated rat aorta by Muller, Bernard, Kleschyov, Andrei L., Stoclet, Jean‐Claude

“…1 The aim of this study was to assess whether or not vasoactive nitric oxide (NO) stores exist within vascular tissue after lipopolysaccharide (LPS)‐treatment…”
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The inducible nitric oxide synthase in vascular and cardiac tissue by Stoclet, Jean-Claude, Muller, Bernard, György, Katalin, Andriantsiothaina, Ramaroson, Kleschyov, Andrei L

“…Expression of the inducible form of nitric oxide synthase (iNOS) has been reported in a variety of cardiovascular diseases. The resulting high output nitric…”
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Induction of nitric oxide production by polyosides from the cell walls of Streptococcus mutans OMZ 175, a gram-positive bacterium, in the rat aorta by MARTIN, V, KLESCHYOV, A. L, KLEIN, J.-P, BERETZ, A

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Inducible NO synthase activity in blood vessels and heart: new insight into cell origin and consequences by Muller, B, Kleschyov, A L, Gyorgy, K, Stoclet, J C

“…Induction of the inducible form of nitric oxide synthase (iNOS) in the vascular and cardiac tissue by several inflammatory stimuli may result in the production…”
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Role of adventitial nitric oxide in vascular hyporeactivity induced by lipopolysaccharide in rat aorta by Kleschyov, Andrei L, Muller, Bernard, Schott, Christa, Stoclet, Jean‐Claude

“…This study was designed to elucidate the role of the adventitia in NO‐mediated vascular effects of lipopolysaccharide (LPS). After incubation of rat aorta with…”
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Nitric oxide‐related cyclic GMP‐independent relaxing effect of N‐acetylcysteine in lipopolysaccharide‐treated rat aorta by Muller, Bernard, Kleschyov, Andrei L., Malblanc, Sophie, Stoclet, Jean‐Claude

“…1 We have recently demonstrated the formation of protein‐bound dinitrosyl‐iron complexes (DNIC) in rat aortic rings exposed to lipopolysaccharide (LPS) and…”
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Triggering role of nitric oxide in the delayed protective effect of monophosphoryl lipid A in rat heart by György, Katalin, Muller, Bernard, Végh, Agnes, Kleschyov, Andrei L, Stoclet, Jean‐Claud

“…The main objective of the present study was to further evaluate the role of nitric oxide (NO) in delayed cardiac protection against ischaemia‐reperfusion…”
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Does Nitric Oxide Mediate the Vasodilator Activity of Nitroglycerin? by Kleschyov, Andrei L, Oelze, Matthias, Daiber, Andreas, Huang, Yale, Mollnau, Hanke, Schulz, Eberhard, Sydow, Karsten, Fichtlscherer, Birgit, Mülsch, Alexander, Münzel, Thomas

“…ABSTRACT—Nitroglycerin (glyceryl trinitrate, GTN) relaxes blood vessels primarily via activation of the soluble guanylyl cyclase (sGC)/cGMP/cGMP-dependent…”
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Spin Trapping of Vascular Nitric Oxide Using Colloid Fe(II)-Diethyldithiocarbamate by Kleschyov, Andrei L., Mollnau, Hanke, Oelze, Mattias, Meinertz, Thomas, Huang, Yale, Harrison, David G., Munzel, Thomas

“…Currently available EPR spin-trapping techniques are not sensitive enough for quantification of basal vascular nitric oxide (NO) production from isolated…”
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Induction of NO production by polyosides from the wall of Streptococcus mutans OMZ175 in the rat aorta by Martin, V, Kleschyov, A L, Schöller, M, Klein, J P, Beretz, A

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Mechanisms of Increased Vascular Superoxide Production in an Experimental Model of Idiopathic Dilated Cardiomyopathy by Mollnau, Hanke, Oelze, Matthias, August, Michael, Wendt, Maria, Daiber, Andreas, Schulz, Eberhard, Baldus, Stephan, Kleschyov, Andrei L, Materne, Anke, Wenzel, Philip, Hink, Ulrich, Nickenig, Georg, Fleming, Ingrid, Münzel, Thomas

“…OBJECTIVE—In the present study, we sought to identify mechanisms underlying increased oxidative stress in vascular tissue in an experimental animal model of…”
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Adventitia-derived nitric oxide in rat aortas exposed to endotoxin: cell origin and functional consequences by Kleschyov, A L, Muller, B, Keravis, T, Stoeckel, M E, Stoclet, J C

“…The role of adventitial cells in bacterial lipopolysaccharide (LPS)-induced vascular nitric oxide (NO) overproduction has been largely ignored. In rat aortas…”
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Novel activation of non‐selective cationic channels by dinitrosyl iron‐thiosulfate in PC12 cells by Giannone, Grégory, Takeda, Kenneth, Kleschyov, Andrei L.

“…1 Low molecular mass dinitrosyl iron complexes (DNICs) are nitrosating agents and it is known that the dinitrosyl iron moiety can be transferred to proteins…”
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Heme oxygenase-1-mediated protection: potential role of nonheme iron-nitric oxide complexes by Kleschyov, Andrei L, Wendt, Maria, Munzel, Thomas

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AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis by Cordero-Herrera, Isabel, Kozyra, Mikael, Zhuge, Zhengbing, Haworth, Sarah McCann, Moretti, Chiara, Peleli, Maria, Caldeira-Dias, Mayara, Jahandideh, Arghavan, Huirong, Han, de Campos Cruz, Josiane, Kleschyov, Andrei L., Montenegro, Marcelo F., Ingelman-Sundberg, Magnus, Weitzberg, Eddie, Lundberg, Jon O., Carlstrom, Mattias

“…Advanced age and unhealthy dietary habits contribute to the increasing incidence of obesity and type 2 diabetes. These metabolic disorders, which are often…”
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Antibacterial mouthwash alters gut microbiome, reducing nutrient absorption and fat accumulation in Western diet-fed mice by Carvalho, Lucas Rannier Ribeiro Antonino, Boeder, Ariela M., Shimari, Miho, Kleschyov, Andrei L., Esberg, Anders, Johansson, Ingegerd, Weitzberg, Eddie, Lundberg, Jon O., Carlstrom, Mattias

“…Prolonged use of antibacterial mouthwash is linked to an increased risk of systemic disease. We aimed to investigate if disturbing the oral microbiota would…”
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Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell by Sun, Chiao-Wang, Yang, Jiangning, Kleschyov, Andrei L, Zhuge, Zhengbing, Carlström, Mattias, Pernow, John, Wajih, Nadeem, Isbell, T Scott, Oh, Joo-Yeun, Cabrales, Pedro, Tsai, Amy G, Townes, Tim, Kim-Shapiro, Daniel B, Patel, Rakesh P, Lundberg, Jon O

“…BACKGROUND:Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be…”
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