Search Results - "KLEMETSDAL, B"

Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population by KLEMETSDAL, B, STRAUME, B, WIST, E, AABARKKE, J

“…Red blood cell (RBC) thiopurine methyltransferase (TPMT), an inactivating pathway of 6-mercaptopurine, is controlled by genetic polymorphism and is subject to…”
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Low catechol-O-methyltransferase activity in a Saami population by KLEMETSDAL, B, STRAUME, B, GIVERHAUG, T, AARBAKKE, J

“…Catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol hormones, neurotransmitters and certain drugs. It is subject to genetic…”
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Intraindividual variability in red blood cell thiopurine methyltransferase activity by GIBERHAUG, T, KEMETSDAL, B, LYSAA, R, AARBAKKE, J

“…Long-term (13 weeks) and circadian (24 hours) intraindividual variability in red blood cell (RBC) thiopurine methyltransferase (TPMT) activity in healthy…”
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Possibilities for therapeutic drug monitoring of azathioprine : 6-thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells by BERGAN, S, RUGSTAD, H. E, KLEMETSDAL, B, GIVERHAUG, T, BENTDAL, Ø, SØDAL, G, HARTMANN, A, AARBAKKE, J, STOKKE, O

“…The objectives of this study were to establish monitoring of azathioprine (AZA) treatment in renal allograft recipients by red blood cell (RBC) 6-thioguanine…”
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Erythrocyte fraction affects red blood cell thiopurine methyltransferase activity by KLEMETSDAL, B, STRAUME, B, LYSAA, R, GIVERHAUG, T, AARBAKKE, J

“…Red blood cell (RBC) thiopurine methyltransferase (TPMT) metabolizes the cytotoxic drugs 6-mercaptopurine and azathioprine. RBC TPMT activity has been reported…”
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Gender difference in red blood cell thiopurine methyltransferase activity by Klemetsdal, B, Wist, E, Aarbakke, J

“…High red blood cell (RBC) thiopurine methyltransferase (TPMT) activity is associated with a higher relapse rate in children with acute lymphoblastic leukaemia…”
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Optimization of azathioprine therapy by measuring 6-thioguanine nucleotides and methylated mercaptopurine in renal allograft recipients by Bergan, S, Rugstad, H E, Bentdal, O, Sødal, G, Hartmann, A, Klemetsdal, B, Aarbakke, J, Stokke, O

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Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms by Otterness, Diane, Szumlanski, Carol, Lennard, Lynne, Klemetsdal, Bjørg, Aarbakke, Jarle, Park‐Hah, Jeong Ok, Iven, Heiko, Schmiegelow, Kjeld, Branum, Earl, O'Brien, John, Weinshilboum, Richard

“…Thiopurine methyltransferase (TPMT) catalyzes the S‐methylation of thiopurine drugs. TPMT activity is regulated by a common genetic polymorphism that is…”
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Is there a basis for prevention of breast cancer with drugs? by Klemetsdal, B

“…The anti-oestrogen drug tamoxifen has led to one of the most important improvements in therapy for breast cancer patients achieved during the last decades…”
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Thiopurine methyltransferase activity in a Korean population sample of children by Park-Hah, J O, Klemetsdal, B, Lysaa, R, Choi, K H, Aarbakke, J

“…Thiopurine methyltransferase (TPMT) is a cytoplasmic enzyme that catalyzes the S-methylation of the cytotoxic drugs 6-mercaptopurine and azathioprine. Red…”
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Interethnic difference in thiopurine methyltransferase activity by Klemetsdal, B, Tollefsen, E, Loennechen, T, Johnsen, K, Utsi, E, Gisholt, K, Wist, E, Aarbakke, J

“…A number of metabolic pathways are subject to both genetic polymorphism and interethnic differences. A catabolic pathway of 6-mercaptopurine, red blood cell…”
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Is there a gender difference in red blood cell thiopurine methyltransferase activity in healthy children? by Klemetsdal, B, Flaegstad, T, Aarbakke, J

“…We have examined red blood cell (RBC) thiopurine methyltransferase (TPMT) activity in a healthy population sample of Norwegian children, age 1-10 years. Boys…”
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Adverse effects of drugs in the elderly. Reasons for hospitalization by Kjustad, L, Klemetsdal, B, Pape, J

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