Search Results - "KLEFFMANN, Torsten"

A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction by Sweetman, Eiren, Kleffmann, Torsten, Edgar, Christina, de Lange, Michel, Vallings, Rosamund, Tate, Warren

“…Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a serious and complex physical illness that affects all body systems with a multiplicity of…”
Get full text

A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic fatigue syndrome by Peppercorn, Katie, Edgar, Christina D., Kleffmann, Torsten, Tate, Warren P.

“…Of those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ~ 10% develop the chronic post-viral debilitating condition, long COVID…”
Get full text

Acetylation, Methylation and Allysine Modification Profile of Viral and Host Proteins during Influenza A Virus Infection by Ahmed, Farjana, Kleffmann, Torsten, Husain, Matloob

“…Protein modifications dynamically occur and regulate biological processes in all organisms. Towards understanding the significance of protein modifications in…”
Get full text

Proteomic characterization of macro-, micro- and nano-extracellular vesicles derived from the same first trimester placenta: relevance for feto-maternal communication by Tong, Mancy, Kleffmann, Torsten, Pradhan, Shantanu, Johansson, Caroline L., DeSousa, Joana, Stone, Peter R., James, Joanna L., Chen, Qi, Chamley, Larry W.

“…Abstract STUDY QUESTION What proteins are carried by extracellular vesicles (EVs) released from normal first trimester placentae? SUMMARY ANSWER One thousand…”
Get full text

Secreted Amyloid Precursor Protein Alpha, a Neuroprotective Protein in the Brain Has Widespread Effects on the Transcriptome and Proteome of Human Inducible Pluripotent Stem Cell-Derived Glutamatergic Neurons Related to Memory Mechanisms by Peppercorn, Katie, Kleffmann, Torsten, Jones, Owen, Hughes, Stephanie, Tate, Warren

“…Secreted amyloid precursor protein alpha (sAPPα) processed from a parent human brain protein, APP, can modulate learning and memory. It has potential for…”
Get full text

Secreted Amyloid Precursor Protein Alpha (sAPPα) Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes by Peppercorn, Katie, Kleffmann, Torsten, Hughes, Stephanie M, Tate, Warren P

“…Secreted amyloid precursor protein alpha (sAPPα), processed from a parent mammalian brain protein, amyloid precursor protein, can modulate learning and memory…”
Get full text

Quantitative comparison of manuka and clover honey proteomes with royal jelly by Paget, Blake W, Kleffmann, Torsten, Whiteman, Kim E, Thomas, Mark F, McMahon, Chris D

“…Royal jelly and honey are two substances produced successively by the worker bee caste. Modern proteomics approaches have been used to explore the protein…”
Get full text

Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals by Lassé, Moritz, Pilbrow, Anna P., Kleffmann, Torsten, Andersson Överström, Elin, von Zychlinski, Anne, Frampton, Christopher M. A., Poppe, Katrina K., Troughton, Richard W., Lewis, Lynley K., Prickett, Timothy C. R., Pemberton, Christopher J., Richards, Arthur M., Cameron, Vicky A.

“…To identify circulating proteins predictive of acute cardiovascular disease events in the general population, we performed a proteomic screen in plasma from…”
Get full text

Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis by Murphy, Eileen L., Singh, Kavindra V., Avila, Bryant, Kleffmann, Torsten, Gregory, Steven T., Murray, Barbara E., Krause, Kurt L., Khayat, Reza, Jogl, Gerwald

“…Enterococcus faecalis is a gram-positive organism responsible for serious infections in humans, but as with many bacterial pathogens, resistance has rendered a…”
Get full text

Earliest known funerary rites in Wallacea after the last glacial maximum by Hawkins, Stuart, Zetika, Gabriella Ayang, Kinaston, Rebecca, Firmando, Yulio Ray, Sari, Devi Mustika, Suniarti, Yuni, Lucas, Mary, Roberts, Patrick, Reepmeyer, Christian, Maloney, Tim, Kealy, Shimona, Stirling, Claudine, Reid, Malcolm, Barr, David, Kleffmann, Torsten, Kumar, Abhishek, Yuwono, Pratiwi, Litster, Mirani, Husni, Muhammad, Ririmasse, Marlon, Mahirta, Mujabuddawat, Muhammad, Harriyadi, O’Connor, Sue

“…The insular region of Wallacea has become a focal point for studying Pleistocene human ecological and cultural adaptations in island environments, however,…”
Get full text

Identification of Active Site Residues of the Siderophore Synthesis Enzyme PvdF and Evidence for Interaction of PvdF with a Substrate-Providing Enzyme by Philem, Priya, Kleffmann, Torsten, Gai, Sinan, Hawkins, Bill C, Wilbanks, Sigurd M, Lamont, Iain L

“…The problematic opportunistic pathogen secretes a siderophore, pyoverdine. Pyoverdine scavenges iron needed by the bacteria for growth and for pathogenicity in…”
Get full text

Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry by Kumar, Vikas, Kleffmann, Torsten, Hampton, Mark B., Cannell, Mark B., Winterbourn, Christine C.

“…There is strong evidence for the involvement of reactive oxygen species in ischemia/reperfusion injury. Although oxidation of individual thiol proteins has…”
Get full text

The Arabidopsis thaliana Chloroplast Proteome Reveals Pathway Abundance and Novel Protein Functions by Kleffmann, Torsten, Russenberger, Doris, von Zychlinski, Anne, Christopher, Wayne, Sjölander, Kimmen, Gruissem, Wilhelm, Baginsky, Sacha

“…Background: Chloroplasts are plant cell organelles of cyanobacterial origin. They perform essential metabolic and biosynthetic functions of global…”
Get full text

Comparison of SPEED, S-Trap, and In-Solution-Based Sample Preparation Methods for Mass Spectrometry in Kidney Tissue and Plasma by Templeton, Evelyn M, Pilbrow, Anna P, Kleffmann, Torsten, Pickering, John W, Rademaker, Miriam T, Scott, Nicola J A, Ellmers, Leigh J, Charles, Christopher J, Endre, Zoltan H, Richards, A Mark, Cameron, Vicky A, Lassé, Moritz

“…Mass spectrometry is a powerful technique for investigating renal pathologies and identifying biomarkers, and efficient protein extraction from kidney tissue…”
Get full text

Development of ULYSSIS, a Tool for the Biosynthesis of Cyclotides and Cyclic Knottins by Handley, Thomas N. G., Kleffmann, Torsten, Butler, Margi I.

“…Many human disorders and discomforts can potentially be treated by peptide-based medicines. There are two major problems in using peptide-based medicines:…”
Get full text

The application of MALDI TOF MS in biopharmaceutical research by Kafka, Alexandra P., Kleffmann, Torsten, Rades, Thomas, McDowell, Arlene

“…The development and quality assessment of modern biopharmaceuticals, particularly protein and peptide drugs, requires an array of analytical techniques to…”
Get full text

Comparing Walker's (2008) skull trait sex estimation standard to proteomic sex estimation for a group of South Asian individuals by Rogers, Laura M., Halcrow, Siân E., Kleffmann, Torsten, King, Charlotte L.

“…This research assesses the potential for misidentification of sex in individuals of South Asian ancestry using the Walker (2008) morphological skull sex…”
Get full text

Identifying Candidate Protein Markers of Acute Kidney Injury in Acute Decompensated Heart Failure by Templeton, Evelyn M, Lassé, Moritz, Kleffmann, Torsten, Ellmers, Leigh J, Palmer, Suetonia C, Davidson, Trent, Scott, Nicola J A, Pickering, John W, Charles, Christopher J, Endre, Zoltan H, Cameron, Vicky A, Richards, A Mark, Rademaker, Miriam T, Pilbrow, Anna P

“…One-quarter of patients with acute decompensated heart failure (ADHF) experience acute kidney injury (AKI)-an abrupt reduction or loss of kidney function…”
Get full text

Proteome Dynamics during Plastid Differentiation in Rice by Kleffmann, Torsten, von Zychlinski, Anne, Russenberger, Doris, Hirsch-Hoffmann, Matthias, Gehrig, Peter, Gruissem, Wilhelm, Baginsky, Sacha

“…We have analyzed proteome dynamics during light-induced development of rice (Oryza sativa) chloroplasts from etioplasts using quantitative two-dimensional gel…”
Get full text

Proteomic analysis of chinook salmon (Oncorhynchus tshawytscha) ovarian fluid by Johnson, Sheri L, Villarroel, Marsha, Rosengrave, Patrice, Carne, Alan, Kleffmann, Torsten, Lokman, P Mark, Gemmell, Neil J

“…The ovarian, or coelomic, fluid that is released with the egg mass of many fishes is increasingly found to play an important role in several biological…”
Get full text