Search Results - "KLEE, George G"

Antibody-Based Protein Multiplex Platforms: Technical and Operational Challenges by Ellington, Allison A, Kullo, Iftikhar J, Bailey, Kent R, Klee, George G

“…The measurement of multiple protein biomarkers may refine risk stratification in clinical settings. This concept has stimulated development of multiplexed…”
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The Prostate Health Index Selectively Identifies Clinically Significant Prostate Cancer by Loeb, Stacy, Sanda, Martin G, Broyles, Dennis L, Shin, Sanghyuk S, Bangma, Chris H, Wei, John T, Partin, Alan W, Klee, George G, Slawin, Kevin M, Marks, Leonard S, van Schaik, Ron H.N, Chan, Daniel W, Sokoll, Lori J, Cruz, Amabelle B, Mizrahi, Isaac A, Catalona, William J

“…Purpose The Prostate Health Index (phi) is a new test combining total, free and [-2]proPSA into a single score. It was recently approved by the FDA and is now…”
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Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation by Spratt, Daniel E, Evans, Michael J, Davis, Brian J, Doran, Michael G, Lee, Man Xia, Shah, Neel, Wongvipat, John, Carnazza, Kathryn E, Klee, George G, Polkinghorn, William, Tindall, Donald J, Lewis, Jason S, Sawyers, Charles L

“…Clinical trials have established the benefit of androgen deprivation therapy (ADT) combined with radiotherapy in prostate cancer. ADT sensitizes prostate…”
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National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers by Sturgeon, Catharine M, Duffy, Michael J, Stenman, Ulf-Hakan, Lilja, Hans, Brunner, Nils, Chan, Daniel W, Babaian, Richard, Bast, Robert C., Jr, Dowell, Barry, Esteva, Francisco J, Haglund, Caj, Harbeck, Nadia, Hayes, Daniel F, Holten-Andersen, Mads, Klee, George G, Lamerz, Rolf, Looijenga, Leendert H, Molina, Rafael, Nielsen, Hans Jorgen, Rittenhouse, Harry, Semjonow, Axel, Shih, Ie-Ming, Sibley, Paul, Soletormos, Gyorgy, Stephan, Carsten, Sokoll, Lori, Hoffman, Barry R, Diamandis, Eleftherios P

“…Updated National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been…”
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Global Methylation Profiling for Risk Prediction of Prostate Cancer by MAHAPATRA, Saswati, KLEE, Eric W, YOUNG, Charles Y. F, ZHIFU SUN, JIMENEZ, Rafael E, KLEE, George G, TINDALL, Donald J, VANAJA DONKENA, Krishna

“…The aim of this study was to investigate the promoter hypermethylation as diagnostic markers to detect malignant prostate cells and as prognostic markers to…”
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A tissue biomarker panel predicting systemic progression after PSA recurrence post-definitive prostate cancer therapy by Nakagawa, Tohru, Kollmeyer, Thomas M, Morlan, Bruce W, Anderson, S Keith, Bergstralh, Eric J, Davis, Brian J, Asmann, Yan W, Klee, George G, Ballman, Karla V, Jenkins, Robert B

“…Many men develop a rising PSA after initial therapy for prostate cancer. While some of these men will develop a local or metastatic recurrence that warrants…”
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The Cistrome and Gene Signature of Androgen Receptor Splice Variants in Castration Resistant Prostate Cancer Cells by Lu, Ji, Lonergan, Peter E, Nacusi, Lucas P, Wang, Liguo, Schmidt, Lucy J, Sun, Zhifu, Van der Steen, Travis, Boorjian, Stephen A, Kosari, Farhad, Vasmatzis, George, Klee, George G, Balk, Steven P, Huang, Haojie, Wang, Chunxi, Tindall, Donald J

“…Purpose Spliced variant forms of androgen receptor were recently identified in castration resistant prostate cancer cell lines and clinical samples. We…”
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Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor‐specific fluorescent ligands by He, Wei, Kularatne, Sumith A., Kalli, Kimberly R., Prendergast, Franklyn G., Amato, Robert J., Klee, George G., Hartmann, Lynn C., Low, Philip S.

“…Quantitation of circulating tumor cells (CTCs) can provide information on the stage of a malignancy, onset of disease progression and response to therapy. In…”
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Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the Mayo Clinic proteomic markers of arteriosclerosis study by Kim, Charles X, Bailey, Kent R, Klee, George G, Ellington, Allison A, Liu, Guanghui, Mosley, Jr, Thomas H, Rehman, Hamid, Kullo, Iftikhar J

“…Cardiovascular disease (CVD) susceptibility differs between men and women and varies with ethnicity. This variability is not entirely explained by conventional…”
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Prospective multicenter evaluation of the Beckman Coulter Prostate Health Index using WHO calibration by Loeb, Stacy, Sokoll, Lori J, Broyles, Dennis L, Bangma, Chris H, van Schaik, Ron H N, Klee, George G, Wei, John T, Sanda, Martin G, Partin, Alan W, Slawin, Kevin M, Marks, Leonard S, Mizrahi, Isaac A, Shin, Sanghyuk S, Cruz, Amabelle B, Chan, Daniel W, Roberts, William L, Catalona, William J

“…Reported prostate specific antigen values may differ substantially among assays using Hybritech® or WHO standardization. The Beckman Coulter® Prostate Health…”
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Absolute Quantification of the Model Biomarker Prostate-Specific Antigen in Serum by LC−MS/MS Using Protein Cleavage and Isotope Dilution Mass Spectrometry by Barnidge, David R, Goodmanson, Marcia K, Klee, George G, Muddiman, David C

“…Protein cleavage-isotope dilution mass spectrometry (PC-IDMS) can be used to quantify proteins, with an isotope-labeled analogue of the peptide fragment used…”
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LC-MS/MS quantification of Zn-α2 glycoprotein : A potential serum biomarker for prostate cancer by BONDAR, Olga P, BARNIDGE, David R, KLEE, Eric W, DAVIS, Brian J, KLEE, George G

“…Abstract Background: Zn-α2 glycoprotein (ZAG) is a relatively abundant glycoprotein that has potential as a biomarker for prostate cancer. We present a…”
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Establishment of Outcome-Related Analytic Performance Goals by KLEE, George G

“…Accrediting organizations require laboratories to establish analytic performance criteria that ensure their tests provide results of the high quality required…”
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Criteria for assigning laboratory measurands to models for analytical performance specifications defined in the 1st EFLM Strategic Conference by Ceriotti, Ferruccio, Fernandez-Calle, Pilar, Klee, George G, Nordin, Gunnar, Sandberg, Sverre, Streichert, Thomas, Vives-Corrons, Joan-Lluis, Panteghini, Mauro

“…This paper, prepared by the EFLM Task and Finish Group on Allocation of laboratory tests to different models for performance specifications (TFG-DM), is…”
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The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis by Patel, Anand H, Harnois, Denise M, Klee, George G, LaRusso, Nicholas F, Gores, Gregory J

“…The diagnosis of cholangiocarcinoma is often difficult, making management approaches problematic. A reliable serum tumor marker for cholangiocarcinoma would be…”
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B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema by Rana, Rimki, Vlahakis, Nicholas E, Daniels, Craig E, Jaffe, Allan S, Klee, George G, Hubmayr, Rolf D, Gajic, Ognjen

“…OBJECTIVE:The role of plasma B-type natriuretic peptide (BNP) in critically ill patients with acute pulmonary edema is controversial. We postulated that a low…”
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Longitudinal Changes of Benign Prostate-specific Antigen and [−2]Proprostate-specific Antigen in Seven Years in a Community-based Sample of Men by Rhodes, Thomas, Jacobson, Debra J, McGree, Michaela E, St. Sauver, Jennifer L, Girman, Cynthia J, Lieber, Michael M, Klee, George G, Demissie, Kitaw, Jacobsen, Steven J

“…Objective To determine the longitudinal changes of benign prostate-specific antigen (BPSA) and [−2]proPSA and how these changes relate to the outcomes. These…”
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Serum sex hormones and measures of benign prostatic hyperplasia by Roberts, Rosebud O., Jacobson, Debra J., Rhodes, Thomas, Klee, George G., Leiber, Michael M., Jacobsen, Steven J.

“…BACKGROUND Despite biologic plausibility, the associations between sex hormones and measures of benign prostatic hyperplasia (BPH) have not been consistently…”
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Human anti-mouse antibodies by Klee, G G

“…Human anti-mouse antibodies (HAMA) are human immunoglobulins with specificity for mouse immunoglobulins. This topic currently is of interest because of the…”
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Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk patient population by Karnes, R Jeffrey, Bergstralh, Eric J, Davicioni, Elai, Ghadessi, Mercedeh, Buerki, Christine, Mitra, Anirban P, Crisan, Anamaria, Erho, Nicholas, Vergara, Ismael A, Lam, Lucia L, Carlson, Rachel, Thompson, Darby J S, Haddad, Zaid, Zimmermann, Benedikt, Sierocinski, Thomas, Triche, Timothy J, Kollmeyer, Thomas, Ballman, Karla V, Black, Peter C, Klee, George G, Jenkins, Robert B

“…Patients with locally advanced prostate cancer after radical prostatectomy are candidates for secondary therapy. However, this higher risk population is…”
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