Search Results - "KJAER, Michael"

Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading by KJAeR, MICHAEL

“…Sports Medicine Research Unit, Department of Rheumatology, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark Kjær, Michael. Role of…”
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Basic components of connective tissues and extracellular matrix: elastin, fibrillin, fibulins, fibrinogen, fibronectin, laminin, tenascins and thrombospondins by Halper, Jaroslava, Kjaer, Michael

“…Collagens are the most abundant components of the extracellular matrix and many types of soft tissues. Elastin is another major component of certain soft…”
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The Effect of Aging and Mechanical Loading on the Metabolism of Articular Cartilage by Jørgensen, Adam El Mongy, Kjær, Michael, Heinemeier, Katja Maria

“…The morphology of articular cartilage (AC) enables painless movement. Aging and mechanical loading are believed to influence development of osteoarthritis…”
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Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial by Beyer, Rikke, Kongsgaard, Mads, Hougs Kjær, Birgitte, Øhlenschlæger, Tommy, Kjær, Michael, Magnusson, S. Peter

“…Background: Previous studies have shown that eccentric training has a positive effect on Achilles tendinopathy, but few randomized controlled trials have…”
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Influence of sex and estrogen on musculotendinous protein turnover at rest and after exercise by Hansen, Mette, Kjaer, Michael

“…Women differ from men with regard to muscle and tendon, most likely because of sex differences in estrogen. The present experimental findings suggest the…”
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Effect of aging and exercise on the tendon by Svensson, Rene B, Heinemeier, Katja Maria, Couppé, Christian, Kjaer, Michael, Magnusson, S Peter

“…Here, we review the literature on how tendons respond and adapt to ageing and exercise. With respect to aging, there are considerable changes early in life,…”
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Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration by Mackey, Abigail L., Magnan, Mélanie, Chazaud, Bénédicte, Kjaer, Michael

“…Key points Accumulation of skeletal muscle extracellular matrix is an unfavourable characteristic of many muscle diseases, muscle injury and sarcopenia. The…”
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The breaking and making of healthy adult human skeletal muscle in vivo by Mackey, Abigail L, Kjaer, Michael

“…While muscle regeneration has been extensively studied in animal and cell culture models, in vivo myogenesis in adult human skeletal muscle has not been…”
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Carbon‐14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover by Heinemeier, Katja Maria, Schjerling, Peter, Øhlenschlæger, Tommy F., Eismark, Christian, Olsen, Jesper, Kjær, Michael

“…ABSTRACT Tendons are essential weight‐bearing structures that are often affected by tendinopathy, which leads to pain and impaired mobility. In healthy…”
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Differentially Activated Macrophages Orchestrate Myogenic Precursor Cell Fate During Human Skeletal Muscle Regeneration by Saclier, Marielle, Yacoub‐Youssef, Houda, Mackey, Abigail L., Arnold, Ludovic, Ardjoune, Hamida, Magnan, Mélanie, Sailhan, Frédéric, Chelly, Jamel, Pavlath, Grace K., Mounier, Rémi, Kjaer, Michael, Chazaud, Bénédicte

“…Macrophages (MPs) exert either beneficial or deleterious effects on tissue repair, depending on their activation/polarization state. They are crucial for adult…”
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Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model by Hoeffner, Rikke, Svensson, Rene B, Dietrich-Zagonel, Franciele, Schefte, Daniel, Kjær, Michael, Eliasson, Pernilla, Magnusson, S Peter

“…Permanent loss of muscle function seen after an Achilles tendon rupture may partly be explained by tendon elongation and accompanying shortening of the muscle…”
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Increased Risk of Tendon Injury Following Structured Care in Patients With Type 2 Diabetes: Post Hoc Analysis of a Large Randomized Controlled Trial With 19 Years of Follow-up by Stausholm, Martin B, Siersma, Volkert, Køster-Rasmussen, Rasmus, Waagepetersen, Asger, Pedersen, Zandra O, Magnusson, S P, Kjær, Michael, Couppé, Christian

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Larger interface area at the human myotendinous junction in type 1 compared with type 2 muscle fibers by Jakobsen, Jens Rithamer, Mackey, Abigail Louise, Koch, Manuel, Imhof, Thomas, Hannibal, Jens, Kjær, Michael, Krogsgaard, Michael Rindom

“…The myotendinous junction (MTJ) is structurally specialized to transmit force. The highly folded muscle membrane at the MTJ increases the contact area between…”
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Radiocarbon dating reveals minimal collagen turnover in both healthy and osteoarthritic human cartilage by Heinemeier, Katja M, Schjerling, Peter, Heinemeier, Jan, Møller, Mathias B, Krogsgaard, Michael R, Grum-Schwensen, Tomas, Petersen, Michael M, Kjaer, Michael

“…The poor regenerative capacity of articular cartilage presents a major clinical challenge and may relate to a limited turnover of the cartilage collagen…”
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Interleukin-6: a growth factor stimulating collagen synthesis in human tendon by ANDERSEN, Mette Bisgaard, PINGEL, Jessica, KJAER, Michael, LANGBERG, Henning

“…Human connective tissue, e.g., tendon, responds dynamically to physical activity, with collagen synthesis being increased after both acute and prolonged…”
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Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men by Karlsen, Anders, Soendenbroe, Casper, Malmgaard‐Clausen, Nikolaj M., Wagener, Frederik, Moeller, Casper Emil, Senhaji, Zouhir, Damberg, Kristine, Andersen, Jesper Løvind, Schjerling, Peter, Kjaer, Michael, Mackey, Abigail L.

“…Blunted muscle hypertrophy and impaired regeneration with aging have been partly attributed to satellite cell (SC) dysfunction. However, true muscle…”
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Collagens in primary frozen shoulder: expression of collagen mRNA isoforms in the different phases of the disease by Marker, Line, Schjerling, Peter, Mackey, Abigail L, Hansen, Thomas, Jakobsen, Jens, Kjær, Michael, Krogsgaard, Michael R

“…Primary frozen shoulder (pFS) has three phases that differ in clinical presentation. It is characterized by contracture of the joint capsule. We hypothesized…”
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How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins? by Agergaard, Jakob, Kjær, Michael

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Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood by Demnitz, Naiara, Madsen, Kathrine Skak, Johnsen, Line K., Kjaer, Michael, Boraxbekk, Carl-Johan, Siebner, Hartwig R.

“…Ageing leads to a decline in white matter microstructure and dexterous function of the hand. In adolescents, it has previously been shown that the degree of…”
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Muscle and blood metabolites during a soccer game : Implications for sprint performance by KRUSTRUP, Peter, MOHR, Magni, STEENSBERG, Adam, BENCKE, Jesper, KJAIR, Michael, BANGSBO, Jens

“…To examine muscle and blood metabolites during soccer match play and relate it to possible changes in sprint performance. Thirty-one Danish fourth division…”
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