Search Results - "KITAZAWA, Sohei"

Prominent CD8‐positive lymphocyte‐associated insulitis immediately after onset of childbirth‐related fulminant type 1 diabetes mellitus observed at autopsy by Kitazawa, Sohei, Kitazawa, Riko

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Laceration of umbilical cord artery by fetus nail—Rare but possible cause of sudden infantile death at birth by Kitazawa, Sohei, Kitazawa, Riko

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RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter by Kitazawa, Riko, Haraguchi, Ryuma, Kohara, Yukihiro, Kitazawa, Sohei

“…Receptor Activator of NF-κB (RANK) expressed on osteoclasts and their precursors is a receptor for RANK ligand (RANKL). Signals transduced by RANKL-RANK…”
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In situ sequence-specific visualization of single methylated cytosine on tissue sections using ICON probe and rolling-circle amplification by Kitazawa, Sohei, Haraguchi, Ryuma, Takaoka, Yuki, Kitazawa, Riko

“…Since epigenetic modifications differ from cell to cell, detecting the DNA methylation status of individual cells is requisite. Therefore, it is important to…”
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Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro by Kohara, Yukihiro, Haraguchi, Ryuma, Kitazawa, Riko, Kitazawa, Sohei

“…Low density lipoprotein receptor-related protein 1 (LRP1), a multifunctional cell surface protein, is expressed in bone marrow-derived macrophages. While LRP1…”
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Histone Modification in Histochemistry and Cytochemistry by Kitazawa, Riko, Haraguchi, Ryuma, Kitazawa, Sohei

“…Keeping chromatin in a stable state is essential for genome stability, scheduled transcription, replication, DNA repair, and precise and reliable chromosome…”
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New Insights into the Pathogenesis of Diabetic Nephropathy: Proximal Renal Tubules Are Primary Target of Oxidative Stress in Diabetic Kidney by Haraguchi, Ryuma, Kohara, Yukihiro, Matsubayashi, Kanako, Kitazawa, Riko, Kitazawa, Sohei

“…Diabetic nephropathy is a major source of end-stage renal failure, affecting about one-third cases of diabetes mellitus. It has long been accepted that…”
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Novel animal model of soft tissue tumor due to aberrant hedgehog signaling activation in pericyte lineage by Haraguchi, Ryuma, Kitazawa, Riko, Kohara, Yukihiro, Imai, Yuuki, Kitazawa, Sohei

“…Pericytes are pluripotent cells that enclose the endothelium of small blood vessels in the whole body. These cells are thought to play a limited role in…”
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Two autopsy cases of wild-type transthyretin cardiac amyloidosis who died 10 days after technetium-99m-pyrophosphate scintigraphy by Takahashi, Koji, Morioka, Hiroe, Sasaki, Daisuke, Yamamura, Nobuhisa, Kitazawa, Sohei, Ueda, Mitsuharu, Sakaue, Tomoki, Enomoto, Daijiro, Uemura, Shigeki, Okura, Takafumi, Ikeda, Shuntaro

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Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of Smo in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss by Kohara, Yukihiro, Haraguchi, Ryuma, Kitazawa, Riko, Imai, Yuuki, Kitazawa, Sohei

“…The functional role of the Hedgehog (Hh)-signaling pathway has been widely investigated in bone physiology/development. Previous studies have, however, focused…”
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Pathologic conditions of hard tissue: role of osteoclasts in osteolytic lesion by Kitazawa, Riko, Haraguchi, Ryuma, Fukushima, Mana, Kitazawa, Sohei

“…Hard tissue homeostasis is regulated by the balance between bone formation by osteoblasts and bone resorption by osteoclasts. This physiologic process allows…”
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Recent Insights into Long Bone Development: Central Role of Hedgehog Signaling Pathway in Regulating Growth Plate by Haraguchi, Ryuma, Kitazawa, Riko, Kohara, Yukihiro, Ikedo, Aoi, Imai, Yuuki, Kitazawa, Sohei

“…The longitudinal growth of long bone, regulated by an epiphyseal cartilaginous component known as the "growth plate", is generated by epiphyseal chondrocytes…”
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ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts by Yan, Minglu, Komatsu, Noriko, Muro, Ryunosuke, Huynh, Nam Cong-Nhat, Tomofuji, Yoshihiko, Okada, Yukinori, Suzuki, Hiroshi I., Takaba, Hiroyuki, Kitazawa, Riko, Kitazawa, Sohei, Pluemsakunthai, Warunee, Mitsui, Yuichi, Satoh, Takashi, Okamura, Tadashi, Nitta, Takeshi, Im, Sin-Hyeog, Kim, Chan Johng, Kollias, George, Tanaka, Sakae, Okamoto, Kazuo, Tsukasaki, Masayuki, Takayanagi, Hiroshi

“…Fibroblasts, the most abundant structural cells, exert homeostatic functions but also drive disease pathogenesis. Single-cell technologies have illuminated the…”
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Acute myocardial infarction caused by coronary mucormycotic embolism by Kitazawa, Sohei, Kitazawa, Riko

“…Described here is a rare cardiac complication attributed to mucormycosis in a 63-year-old woman who developed sudden cardiac arrest and pulmonary insufficiency…”
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Histochemistry, Cytochemistry and Epigenetics by Kitazawa, Sohei, Ohno, Teruyuki, Haraguchi, Ryuma, Kitazawa, Riko

“…Over the past few decades, many researchers have individually identified tumor-related genes, and have accumulated information on their basic research in a…”
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CpG Methylation of Receptor Activator NF-κB (RANK) Gene Promoter Region Delineates Senescence-Related Decrease of RANK Gene Expression by Kitazawa, Riko, Haraguchi, Ryuma, Murata, Yuki, Takaoka, Yuki, Kitazawa, Sohei

“…While the rapid decrease in estrogen is well known as the main cause of postmenopausal osteoporosis in women, the precise pathogenesis of senile osteoporosis…”
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sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss by Haraguchi, Ryuma, Kitazawa, Riko, Mori, Kiyoshi, Tachibana, Ryosuke, Kiyonari, Hiroshi, Imai, Yuuki, Abe, Takaya, Kitazawa, Sohei

“…sFRP4 is an extracellular Wnt antagonist that fine-tunes its signal activity by direct binding to Wnts. Bone fragility under oxidative stress by diabetes and…”
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Localization of DLL1- and NICD-positive osteoblasts in cortical bone during postnatal growth in rats by Kohara, Yukihiro, Kitazawa, Sohei, Kitazawa, Riko, Haraguchi, Ryuma, Arai, Kiyotaka, Amasaki, Hajime, Soeta, Satoshi

“…The long bone midshaft expands by forming primary osteons at the periosteal surface of cortical bone in humans and rodents. Osteoblastic bone formation in the…”
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Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter by Kitazawa, Riko, Kinto-Shibahara, Satomi, Haraguchi, Ryuma, Kohara, Yukihiro, Kitazawa, Sohei

“…Receptor activator of NF-κB (RANK) expressed on osteoclasts and their precursors is a receptor for RANK ligand (RANKL). Signals transduced by RANKL-RANK…”
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New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development by Haraguchi, Ryuma, Yamada, Gen, Murashima, Aki, Matsumaru, Daisuke, Kitazawa, Riko, Kitazawa, Sohei

“…The reproductive tract in mammals emerges from two ductal systems during embryogenesis: Wolffian ducts (WDs) and Mullerian ducts (MDs). Most of the female…”
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