Search Results - "KITAURA, Yasushi"

Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations by PUREVJAV, Enkhsaikhan, ARIMURA, Takuro, OMMEN, Steve R, SHIBATA, Hiroki, TAKAHASHI, Megumi, ITOH-SATOH, Manatsu, MCKENNA, William J, MURPHY, Ross T, LABEIT, Siegfried, YAMANAKA, Yoichi, MACHIDA, Noboru, PARK, Jeong-Euy, AUGUSTIN, Sibylle, ALEXANDER, Peta M. A, WEINTRAUB, Robert G, KITAURA, Yasushi, ACKERMAN, Michael J, KIMURA, Akinori, TOWBIN, Jeffrey A, HUBY, Anne-Cecile, TAKAGI, Ken, NUNODA, Shinichi, KEARNEY, Debra L, TAYLOR, Michael D, TERASAKI, Fumio, BOS, Johan M

“…Abnormalities in Z-disc proteins cause hypertrophic (HCM), dilated (DCM) and/or restrictive cardiomyopathy (RCM), but disease-causing mechanisms are not fully…”
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Atrial natriuretic peptide exerts protective action against angiotensin II-induced cardiac remodeling by attenuating inflammation via endothelin-1/endothelin receptor A cascade by Fujita, Shuichi, Shimojo, Naoshi, Terasaki, Fumio, Otsuka, Kaoru, Hosotani, Noriko, Kohda, Yuka, Tanaka, Takao, Nishioka, Tomohiro, Yoshida, Toshimichi, Hiroe, Michiaki, Kitaura, Yasushi, Ishizaka, Nobukazu, Imanaka-Yoshida, Kyoko

“…We aimed to investigate whether atrial natriuretic peptide (ANP) attenuates angiotensin II (Ang II)-induced myocardial remodeling and to clarify the possible…”
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Active HSF1 Significantly Suppresses Polyglutamine Aggregate Formation in Cellular and Mouse Models by Fujimoto, Mitsuaki, Takaki, Eiichi, Hayashi, Tetsuya, Kitaura, Yasushi, Tanaka, Yasunori, Inouye, Sachiye, Nakai, Akira

“…Polyglutamine diseases are inherited neurodegenerative diseases characterized by misfolding and aggregation of proteins possessing expanded polyglutamine…”
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Impact of outdoor temperature on prewaking morning surge and nocturnal decline in blood pressure in a Japanese population by Murakami, Shougo, Otsuka, Kuniaki, Kono, Tatsuji, Soyama, Akiko, Umeda, Tatsuya, Yamamoto, Naomune, Morita, Hideaki, Yamanaka, Gaku, Kitaura, Yasushi

“…Seasonal variations in blood pressure (BP) have often been attributed to meteorological factors, especially changes in outdoor temperature. We evaluated the…”
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Enhanced Expression of the S100A8/A9 Complex in Acute Myocardial Infarction Patients by Katashima, Takashi, Naruko, Takahiko, Terasaki, Fumio, Fujita, Masatoshi, Otsuka, Kaoru, Murakami, Shougo, Sato, Akira, Hiroe, Michiaki, Ikura, Yoshihiro, Ueda, Makiko, Ikemoto, Masaki, Kitaura, Yasushi

“…Background: S100A8/A9 complex (S100A8/A9) is expressed in activated human neutrophils and macrophages. Enhanced expression of S100A8/A9 in atherosclerotic…”
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Cardiovascular protection by ezetimibe and influence on oxidative stress in mice exposed to intermittent hypoxia by Kato, Ryuji, Nishioka, Satoshi, Nomura, Atsuo, Ijiri, Yoshio, Miyamura, Masatoshi, Ukimura, Akira, Okada, Yoshikatsu, Kitaura, Yasushi, Hayashi, Tetsuya

“…Ezetimibe is as an inhibitor of NPC1L1 protein, which has a key role in cholesterol absorption. The aim of this study was to evaluate the influence of…”
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Effect of Efonidipine on TGF-β1–Induced Cardiac Fibrosis Through Smad2-Dependent Pathway in Rat Cardiac Fibroblasts by Lei, Bai, Hitomi, Hirofumi, Mori, Tatsuhiko, Nagai, Yukiko, Deguchi, Kazushi, Mori, Hirohito, Masaki, Tsutomu, Nakano, Daisuke, Kobori, Hiroyuki, Kitaura, Yasushi, Nishiyama, Akira

“…Transforming growth factor beta-1 (TGF-β1) plays a critical role in progression of cardiac fibrosis, which may involve intracellular calcium change. We…”
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Pitavastatin reduces oxidative stress and attenuates intermittent hypoxia-induced left ventricular remodeling in lean mice by Inamoto, Sakiko, Yoshioka, Toshitaka, Yamashita, Chika, Miyamura, Masatoshi, Mori, Tatsuhiko, Ukimura, Akira, Matsumoto, Chika, Matsumura, Yasuo, Kitaura, Yasushi, Hayashi, Tetsuya

“…We have reported previously that intermittent hypoxia related to sleep apnea induces cardiovascular remodeling secondary to the oxidative stress. The aim of…”
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Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice by Inoue, Nao, Muramatsu, Michiko, Jin, Denan, Takai, Shinji, Hayashi, Tetsuya, Katayama, Hiroshi, Kitaura, Yasushi, Tamai, Hiroshi, Miyazaki, Mizuo

“…Abstract Objective Chymase may play an important role in abdominal aortic aneurysm (AAA) development through matrix metalloproteinase (MMP)-9 activation. The…”
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Higher Serum Tenascin-C Levels Reflect the Severity of Heart Failure, Left Ventricular Dysfunction and Remodeling in Patients With Dilated Cardiomyopathy by Terasaki, Fumio, Okamoto, Hiroshi, Onishi, Katsuya, Sato, Akira, Shimomura, Hiroaki, Tsukada, Bin, Imanaka-Yoshida, Kyoko, Hiroe, Michiaki, Yoshida, Toshimichi, Kitaura, Yasushi, Kitabatake, Akira, Study Group for Intractable Diseases by a Grant from the Ministry of Health, Labor and Welfare of Japan

“…Background Tenascin-C (TN-C), an extracellular matrix glycoprotein, is specifically expressed at high levels during embryonic development, but not in the adult…”
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Comparison of the Acute Effects of Right Ventricular Apical Pacing and Biventricular Pacing in Patients with Heart Failure by Kanzaki, Hideaki, Satomi, Kazuhiro, Noda, Takashi, Shimizu, Wataru, Kamakura, Shiro, Kitaura, Yasushi, Ishizaka, Nobukazu, Kitakaze, Masafumi

“…Objective Upgrading to biventricular (BiV) pacing benefits heart failure patients with right ventricular (RV) apical pacing. However, the impact of switching…”
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High prevalence of chronic myocarditis in dilated cardiomyopathy referred for left ventriculoplasty: expression of tenascin C as a possible marker for inflammation by Tsukada, Bin, MD, Terasaki, Fumio, MD, PhD, Shimomura, Hiroaki, MD, PhD, Otsuka, Koji, MD, Otsuka, Kaoru, MD, Katashima, Takashi, MD, Fujita, Shuichi, MD, Imanaka-Yoshida, Kyoko, MD, PhD, Yoshida, Toshimichi, MD, PhD, Hiroe, Michiaki, MD, PhD, Kitaura, Yasushi, MD, PhD

“…Summary The objectives of this study were to analyze the incidence of chronic myocarditis in dilated cardiomyopathy and to evaluate the diagnostic value of…”
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Angiotensin II Receptor Blocker Reduces Oxidative Stress and Attenuates Hypoxia-Induced Left Ventricular Remodeling in Apolipoprotein E-Knockout Mice by Yamashita, Chika, Hayashi, Tetsuya, Mori, Tatsuhiko, Tazawa, Naoko, Kwak, Chol-Jun, Nakano, Daisuke, Sohmiya, Koichi, Okada, Yoshikatsu, Kitaura, Yasushi, Matsumura, Yasuo

“…Elevated superoxide formation in cardiac extracts of apolipoprotein E-knockout (apoE-KO) mice has been reported. In addition, we previously reported that…”
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Chymase Plays an Important Role in Left Ventricular Remodeling Induced by Intermittent Hypoxia in Mice by Matsumoto, Chika, Hayashi, Tetsuya, Kitada, Kento, Yamashita, Chika, Miyamura, Masatoshi, Mori, Tatsuhiko, Ukimura, Akira, Ohkita, Mamoru, Jin, Denan, Takai, Shinji, Miyazaki, Mizuo, Okada, Yoshikatsu, Kitaura, Yasushi, Matsumura, Yasuo

“…Intermittent hypoxia caused by sleep apnea is associated with cardiovascular disease. Chymase has been reported to play an important role in the development of…”
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Suppression of inflammation in rat autoimmune myocarditis by S100A8/A9 through modulation of the proinflammatory cytokine network by Otsuka, Kaoru, Terasaki, Fumio, Ikemoto, Masaki, Fujita, Shuichi, Tsukada, Bin, Katashima, Takashi, Kanzaki, Yumiko, Sohmiya, Koichi, Kono, Tatsuji, Toko, Haruhiro, Fujita, Masatoshi, Kitaura, Yasushi

“…Aims S100A8/A9 is expressed in activated monocytes/macrophages and assumed to be heavily involved in the pathogenesis of acute inflammation. Although several…”
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Chronic Hypoxia Accelerates the Progression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Nakano, Daisuke, Hayashi, Tetsuya, Tazawa, Naoko, Yamashita, Chika, Inamoto, Sakiko, Okuda, Nobuaki, Mori, Tatsuhiko, Sohmiya, Koichi, Kitaura, Yasushi, Okada, Yoshikatsu, Matsumura, Yasuo

“…The aim of this study was to investigate the effect of chronic hypoxia on the development and progression of atherosclerosis in apolipoprotein E-knockout…”
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Sarcoidosis does not belong to or overlap with immunoglobulin G4–related diseases based on an assessment of serum immunoglobulin G4 levels in cardiac and noncardiac sarcoidosis by Terasaki, Fumio, MD, PhD, Tsuji, Motomu, MD, PhD, Kizawa, Shun, MD, Fujita, Shuichi, MD, Kanzaki, Yumiko, MD, PhD, Kitaura, Yasushi, MD, PhD, Ishizaka, Nobukazu, MD, PhD

“…Summary Although sarcoidosis may exhibit histopathologic features similar to those of a newly emerging clinical entity, immunoglobulin G4–related sclerosing…”
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Effects of Acarbose on the Acceleration of Postprandial Hyperglycemia– Induced Pathological Changes Induced by Intermittent Hypoxia in Lean Mice by Miyamura, Masatoshi, Schnell, Oliver, Yamashita, Chika, Yoshioka, Toshitaka, Matsumoto, Chika, Mori, Tatsuhiko, Ukimura, Akira, Kitaura, Yasushi, Matsumura, Yasuo, Ishizaka, Nobukazu, Hayashi, Tetsuya

“…Postprandial hyperglycemia (PPH) and intermittent hypoxia related to the sleep apnea syndrome are important predictors of cardiovascular disease. We…”
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Involvement of Vascular Angiotensin II-Forming Enzymes in the Progression of Aortic Abdominal Aneurysms in Angiotensin II- Infused ApoE-Deficient Mice by Inoue, Nao, Muramatsu, Michiko, Jin, Denan, Takai, Shinji, Hayashi, Tetsuya, Katayama, Hiroshi, Kitaura, Yasushi, Tamai, Hiroshi, Miyazaki, Mizuo

“…Aim: Angiotensin (Ang) II-induced abdominal aortic aneurysm (AAA) in apoE-deficient mice has been used as a model of human AAA, but it has been unclear why the…”
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National Survey of Fulminant Myocarditis in Japan: Therapeutic Guidelines and Long-Term Prognosis of Using Percutaneous Cardiopulmonary Support for Fulminant Myocarditis (Special Report From a Scientific Committee) by Aoyama, Naoyoshi, Izumi, Tohru, Hiramori, Katsuhiko, Isobe, Mitsuaki, Kawana, Masatoshi, Hiroe, Michiaki, Hishida, Hitoshi, Kitaura, Yasushi, Imaizumi, Tsutomu, Japanese Investigators of Fulminant Myocarditis

“…Although fulminant myocarditis is known as a fatal disease, patients have been able to recover and return to normal life with the help of mechanical…”
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