Search Results - "KITAS, E"
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Dioleoylmelittin as a Novel Serum-Insensitive Reagent for Efficient Transfection of Mammalian Cells
Published in Bioconjugate chemistry (01-01-1997)“…Amphipathic peptides can be useful effectors to enhance gene delivery. However, peptide/DNA complexes usually require additional effectors, such as fusogenic…”
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Endothelin-Converting Enzyme-1 Inhibition and Growth of Human Glioblastoma Cells
Published in Journal of medicinal chemistry (27-01-2005)“…Endothelin-1 (ET-1) is mitogenic and/or antiapoptotic in human cancers, and antagonists to ET-1 receptors are under evaluation for cancer treatment. Inhibition…”
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Labelling of CRF1 and CRF2 receptors using the novel radioligand, [3H]-urocortin
Published in Neuropharmacology (01-10-1997)“…The binding of the novel radioligand, [3H]-rat urocortin to homogenates of rat cerebellum and homogenates of cells stably transfected with the human CRF1, rat…”
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Binding of Oligoarginine to Membrane Lipids and Heparan Sulfate: Structural and Thermodynamic Characterization of a Cell-Penetrating Peptide
Published in Biochemistry (Easton) (22-02-2005)“…Cell-penetrating peptides (CPPs) comprise a group of arginine-rich oligopeptides that are able to deliver exogenous cargo into cells. A first step in the…”
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Substrate specificities of catalytic fragments of protein tyrosine phosphatases (HPTPβ, LAR, and CD45) toward phosphotyrosylpeptide substrates and thiophosphotyrosylated peptides as inhibitors
Published in Protein science (01-06-1993)“…The transmembrane PTPase HPTPβ differs from its related family members in having a single rather than a tandemly duplicated cytosolic catalytic domain. We have…”
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The influence of strongly acidic groups on the protonation of peptides in electrospray MS
Published in Journal of mass spectrometry. (01-10-1997)“…In order to obtain experimental data on the question of compensation of positive charges by anionic groups in multiply charged ions of polyfunctional molecules…”
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SEAP expression in transiently transfected mammalian cells grown in serum-free suspension culture
Published in Cytotechnology (Dordrecht) (01-05-2003)“…A transient transfection process was established using a novel 'in-house' developed transfection reagent, Ro-1539. It allows rapid production of large…”
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Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from Escherichia coli expression systems: purification and characterization for specificity and mechanism
Published in Biochemistry (Easton) (14-01-1992)“…The cytoplasmic domains of two human transmembrane protein tyrosine phosphatases (PTPases), LAR and CD45, have been expressed in Escherichia coli, purified to…”
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NMR analysis of regioselectivity in dephosphorylation of a triphosphotyrosyl dodecapeptide autophosphorylation site of the insulin receptor by a catalytic fragment of LAR phosphotyrosine phosphatase
Published in Protein science (01-10-1992)“…An autophosphorylation site in the activated insulin receptor tyrosine kinase domain has three tyrosines phosphorylated when fully activated. To begin to…”
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Phosphorylation of src-phosphopeptides by casein kinases-1 and -2: favourable effect of phosphotyrosine
Published in Biochemical and biophysical research communications (31-07-1990)“…The synthetic phosphotyrosyl tridecapeptide H-Arg-Leu-Ile-Glu-Asp-Asn-Glu-Tyr(P)-Thr-Ala-Arg-Gln-Gly-OH, reproducing a major phosphoacceptor site of protein…”
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Structural and Thermodynamic Aspects of the Interaction between Heparan Sulfate and Analogues of Melittin
Published in Biochemistry (Easton) (07-03-2006)“…Melittin is an amphipathic cationic peptide derived from honeybee venom with well-known cytolytic and antimicrobial properties. When coupled to cationic…”
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Non-radioactive determination of PTH and dabsyl phosphoamino acids by capillary electrophoresis
Published in Chromatographia (01-04-1992)Get full text
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Chemical synthesis of an O-phosphorylated tyrosine analogue of human angiotensin II, [Tyr(P)4] angiotensin II, and its vasoconstrictor effect in intact sheep
Published in Peptide research (01-07-1993)“…The derivative N alpha-fluorenylmethoxy-carbonyl-O-dimethylphosphono-L-tyrosi ne was utilized in continuous-flow solid-phase synthesis to prepare the…”
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Structure-based design of peptidomimetic antagonists of p56(lck) SH2 domain
Published in Bioorganic & medicinal chemistry letters (20-05-2002)“…Starting from the tetrapeptide Ac-pYEEI-NHMe and using a structure-based approach, we have designed and synthesised a peptidomimetic ligand for p56(lck) SH2…”
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Purification and characterization of a soluble catalytic fragment of the human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase from an Escherichia coli expression system
Published in Biochemistry (Easton) (25-06-1991)“…A 350 amino acid soluble fragment of the intracellular catalytic domain of the human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase…”
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Labelling of CRF 1 and CRF 2 receptors using the novel radioligand, [ 3H]-urocortin
Published in Neuropharmacology (1997)“…The binding of the novel radioligand, [ 3H]-rat urocortin to homogenates of rat cerebellum and homogenates of cells stably transfected with the human CRF 1,…”
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Labelling of CRF sub(1) and CRF sub(2) receptors using the novel radioligand, [ super(3)H]-urocortin
Published in Neuropharmacology (01-10-1997)“…The binding of the novel radioligand, [ super(3)H]-rat urocortin to homogenates of rat cerebellum and homogenates of cells stably transfected with the human…”
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Purification and characterization of active recombinant human napsin A
Published in European journal of biochemistry (01-05-2000)“…Recombinant human napsin A expressed in human embryonic kidney 293 cells was purified to homogeneity by a single‐step procedure using part of napsin A…”
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