Search Results - "KITAJKA, Klara"

Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters by Puskás, László G., Kitajka, Klara, Vizler, Csaba, Szebeni, G. J.

“…One of the hallmarks of cancer-related inflammation is the recruitment of monocyte-macrophage lineage cells to the tumor microenvironment. These tumor…”
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Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic Targets by Szebeni, Gabor J, Vizler, Csaba, Nagy, Lajos I, Kitajka, Klara, Puskas, Laszlo G

“…Since the observation of Virchow, it has long been known that the tumor microenvironment constitutes the soil for the infiltration of inflammatory cells and…”
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Hypothalamic gene expression in ω-3 PUFA-deficient male rats before, and following, development of hypertension by Begg, Denovan P, Puskás, László G, Kitajka, Klara, Ménesi, Dalma, Allen, Andrew M, Li, Duo, Mathai, Michael L, Shi, Jian R, Sinclair, Andrew J, Weisinger, Richard S

“…Dietary deficiency of ω-3 fatty acids (ω-3 DEF) produces hypertension in later life. This study examined the effect of ω-3 DEF on blood pressure and…”
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High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity by Fabian, Gabriella, Farago, Nora, Feher, Liliana Z, Nagy, Lajos I, Kulin, Sandor, Kitajka, Klara, Bito, Tamas, Tubak, Vilmos, Katona, Robert L, Tiszlavicz, Laszlo, Puskas, Laszlo G

“…Toxicogenomics, based on the temporal effects of drugs on gene expression, is able to predict toxic effects earlier than traditional technologies by analyzing…”
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Docosahexaenoic Acid-Containing Phospholipid Molecular Species in Brains of Vertebrates by Farkas, Tibor, Kitajka, Klara, Fodor, Elfrieda, Csengeri, Istvan, Lahdes, Eila, Yeo, Young K., Krasznai, Zoltan, Halver, John E.

“…The fatty acid composition of phospholipids and the contents of docosahexaenoic acid (DHA)-containing diacyl phosphatidylcholine and diacyl…”
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Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells by Antal, Otilia, Péter, Mária, Hackler, László, Mán, Imola, Szebeni, Gábor, Ayaydin, Ferhan, Hideghéty, Katalin, Vigh, László, Kitajka, Klára, Balogh, Gábor, Puskás, Laszló G

“…Previous studies have demonstrated that gamma-linolenic acid (GLA) is effective against glioma cells under both in vitro and in vivo conditions. In the present…”
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Effects of Dietary Omega-3 Polyunsaturated Fatty Acids on Brain Gene Expression by Kitajka, Klára, Sinclair, Andrew J., Weisinger, Richard S., Weisinger, Harrison S., Mathai, Michael, Jayasooriya, Anura P., Halver, John E., Puskás, László G.

“…Polyunsaturated fatty acids (PUFA) are essential structural components of the central nervous system. Their role in controlling learning and memory has been…”
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The Role of n-3 Polyunsaturated Fatty Acids in Brain: Modulation of Rat Brain Gene Expression by Dietary n-3 Fatty Acids by Kitajka, Klára, Puskás, László G., Zvara, Ágnes, Hackler, László, Barceló-Coblijn, Gwendolyn, Yeo, Young K., Farkas, Tibor

“…Rats were fed either a high linolenic acid (perilla oil) or high eicosapentaenoic + docosahexaenoic acid (fish oil) diet (8%), and the fatty acid and molecular…”
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MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes by Faragó, Nóra, Fehér, Liliána Z, Kitajka, Klára, Das, Undurti N, Puskás, László G

“…Polyunsaturated fatty acids (PUFAs) such as γ-linolenic acid (GLA), arachidonic acid (AA) and docosahexaenoic acid (DHA) have cytotoxic action on glioma cells…”
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Altered response to mirtazapine on gene expression profile of lymphocytes from Alzheimer's patients by Palotás, András, Puskás, László G., Kitajka, Klára, Palotás, Miklós, Molnár, József, Pákáski, Magdolna, Janka, Zoltán, Penke, Botond, Kálmán, János

“…Antidepressants are widely used in the treatment of mood disorders associated with dementia, however little information is available on their effect at the…”
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Combination of unsaturated fatty acids and ionizing radiation on human glioma cells: cellular, biochemical and gene expression analysis by Antal, Otilia, Hackler, Jr, László, Shen, Junhui, Mán, Imola, Hideghéty, Katalin, Kitajka, Klára, Puskás, László G

“…Based on previous observations a potential resort in the therapy of the particularly radioresistant glioma would be its treatment with unsaturated fatty acids…”
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Short-Term Administration of Omega 3 Fatty Acids from Fish Oil Results in Increased Transthyretin Transcription in Old Rat Hippocampus by Puskás, László G., Kitajka, Klára, Nyakas, Csaba, Barcelo-Coblijn, Gwendolyn, Farkas, Tibor

“…Reduced brain levels of long chain polyunsaturated fatty acids [arachidonic acid and docosahexanoic acid (DHA)] are observed in elderly subjects and patients…”
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Modification by Docosahexaenoic Acid of Age-Induced Alterations in Gene Expression and Molecular Composition of Rat Brain Phospholipids by Barceló-Coblijn, Gwendolyn, Hőgyes, Endre, Kitajka, Klára, Puskás, László G., Zvara, Ágnes, Hackler, László, Nyakas, Csaba, Penke, Zsuzsa, Farkas, Tibor

“…Advanced age is associated with reduced brain levels of long-chain polyunsaturated fatty acids, arachidonic acid (AA) and docosahexaenoic acid (DHA). Memory…”
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Influence of the membrane lipid structure on signal processing via G protein-coupled receptors by Yang, Qing, Alemany, Regina, Casas, Jesús, Kitajka, Klára, Lanier, Stephen M, Escribá, Pablo V

“…We have recently reported that lipid structure regulates the interaction with membranes, recruitment to membranes, and distribution to membrane domains of…”
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Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells by Puskás, László G, Fehér, Liliána Z, Vizler, Csaba, Ayaydin, Ferhan, Rásó, Erzsébet, Molnár, Eszter, Magyary, István, Kanizsai, Iván, Gyuris, Márió, Madácsi, Ramóna, Fábián, Gabriella, Farkas, Klaudia, Hegyi, Péter, Baska, Ferenc, Ozsvári, Béla, Kitajka, Klára

“…Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs…”
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Melatonin-induced gene expression changes and its preventive effects on adriamycin-induced lipid peroxidation in rat liver by Catalá, Angel, Zvara, Ágnes, Puskás, László G., Kitajka, Klára

“…:  Adriamycin (ADR) provokes lipid peroxidation process, while melatonin (MEL) is a free radical scavenger that has been found to protect against lipid…”
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Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study by Puskás, László G., Nagy, Zsolt B., Giricz, Zoltán, Ónody, Annamária, Csonka, Csaba, Kitajka, Klára, Hackler, László, Zvara, Ágnes, Ferdinandy, Péter

“…To profile gene expression patterns involved in the direct myocardial effect of cholesterol-enriched diet-induced hyperlipidemia, we monitored global gene…”
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Perinatal omega-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood by Jayasooriya, A.P, Ackland, M.L, Mathai, M.L, Sinclair, A.J, Weisinger, H.S, Weisinger, R.S, Halver, J.E, Kitajka, K, Puskas, L.G

“…Dietary ω-3 polyunsaturated fatty acid (PUFA) influences the expression of a number of genes in the brain. Zinc transporter (ZnT) 3 has been identified as a…”
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Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model by Nagy, Lajos I, Molnár, Eszter, Kanizsai, Iván, Madácsi, Ramóna, Ózsvári, Béla, Fehér, Liliána Z, Fábián, Gabriella, Marton, Annamária, Vizler, Csaba, Ayaydin, Ferhan, Kitajka, Klára, Hackler, Jr, László, Mátés, Lajos, Deák, Ferenc, Kiss, Ibolya, Puskás, László G

“…Hepatocellular carcinoma (HCC) is the most frequent and aggressive primary tumor of the liver and it has limited treatment options. In this study, we report…”
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Nutrition and immune system: certain fatty acids differently modify membrane composition and consequently kinetics of KV1.3 channels of human peripheral lymphocytes by Székely, Andrea, Kitajka, Klára, Panyi, György, Márián, Teréz, Gáspár, Rezsö, Krasznai, Zoltán

“…Potassium (K(+)) channels of human peripheral lymphocytes play a considerable role in the signalling processes required for immune responses. Modification of…”
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