Search Results - "KISTNER, Emily O"

Let-7 Expression Defines Two Differentiation Stages of Cancer by Shell, Scott, Park, Sun-Mi, Radjabi, Amir Reza, Schickel, Robert, Kistner, Emily O., Jewell, David A., Feig, Christine, Lengyel, Ernst, Peter, Marcus E.

“…The early phases of carcinogenesis resemble embryonic development, often involving the reexpression of embryonic mesenchymal genes. The NCI60 panel of human…”
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SCAN: SNP and copy number annotation by Gamazon, Eric R., Zhang, Wei, Konkashbaev, Anuar, Duan, Shiwei, Kistner, Emily O., Nicolae, Dan L., Dolan, M. Eileen, Cox, Nancy J.

“…Motivation: Genome-wide association studies (GWAS) generate relationships between hundreds of thousands of single nucleotide polymorphisms (SNPs) and complex…”
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Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via α5-Integrin, which Is a Therapeutic Target by SAWADA, Kenjiro, MITRA, Anirban K, PETER, Marcus E, RAMAKRISHNAN, Vanitha, YAMADA, S. Diane, LENGYEL, Ernst, REZA RADJABI, A, BHASKAR, Vinay, KISTNER, Emily O, TRETIAKOVA, Maria, JAGADEESWARAN, Sujatha, MONTAG, Anthony, BECKER, Amy, KENNY, Hilary A

“…Abstract E-cadherin loss is frequently associated with ovarian cancer metastasis. Given that adhesion to the abdominal peritoneum is the first step in ovarian…”
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Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study by Silverberg, Mark S, Cho, Judy H, Rioux, John D, McGovern, Dermot P B, Wu, Jing, Annese, Vito, Achkar, Jean-Paul, Goyette, Philippe, Scott, Regan, Xu, Wei, Barmada, M Michael, Klei, Lambertus, Daly, Mark J, Abraham, Clara, Bayless, Theodore M, Bossa, Fabrizio, Griffiths, Anne M, Ippoliti, Andrew F, Lahaie, Raymond G, Latiano, Anna, Paré, Pierre, Proctor, Deborah D, Regueiro, Miguel D, Steinhart, A Hillary, Targan, Stephan R, Schumm, L Philip, Kistner, Emily O, Lee, Annette T, Gregersen, Peter K, Rotter, Jerome I, Brant, Steven R, Taylor, Kent D, Roeder, Kathryn, Duerr, Richard H

“…Richard Duerr and colleagues present a genome-wide association study of ulcerative colitis. They identify new risk loci on chromosomes 1p36 and 12q15…”
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Identification of Genetic Variants Contributing to Cisplatin-Induced Cytotoxicity by Use of a Genomewide Approach by Huang, R. Stephanie, Duan, Shiwei, Shukla, Sunita J., Kistner, Emily O., Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Dolan, M. Eileen

“…Cisplatin, a platinating agent commonly used to treat several cancers, is associated with nephrotoxicity, neurotoxicity, and ototoxicity, which has hindered…”
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A Genome-Wide Approach to Identify Genetic Variants That Contribute to Etoposide-Induced Cytotoxicity by Huang, R. Stephanie, Duan, Shiwei, Bleibel, Wasim K., Kistner, Emily O., Zhang, Wei, Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Cox, Nancy J., Dolan, M. Eileen

“…Large interindividual variance has been observed in sensitivity to drugs. To comprehensively decipher the genetic contribution to these variations in drug…”
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Genetic variants contributing to daunorubicin-induced cytotoxicity by Huang, R Stephanie, Duan, Shiwei, Kistner, Emily O, Bleibel, Wasim K, Delaney, Shannon M, Fackenthal, Donna L, Das, Soma, Dolan, M Eileen

“…Identifying heritable genetic variants responsible for chemotherapeutic toxicities has been challenging due in part to its multigenic nature. To date, there is…”
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Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans by Huang, R Stephanie, Duan, Shiwei, Kistner, Emily O, Hartford, Christine M, Dolan, M Eileen

“…To gain a better understanding of the genetic variants associated with carboplatin-induced cytotoxicity in individuals of African descent, we present a…”
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Effect of population and gender on chemotherapeutic agent-induced cytotoxicity by Huang, Rong Stephanie, Kistner, Emily O, Bleibel, Wasim K, Shukla, Sunita J, Dolan, M Eileen

“…Large interindividual variance is observed in both response and toxicity associated with chemotherapy. Our goal is to identify factors that contribute to…”
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Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy by HUILING LI, ROMIEU, Isabelle, HAO WU, SIENRA-MONGE, Juan-Jose, RAMIREZ-AGUILAR, Matiana, DEL RIO-NAVARRO, Blanca Estela, DEL LARA-SANCHEZ, Irma Carmen, KISTNER, Emily O, GJESSING, Hakon K, LONDON, Stephanie J

“…Transforming growth factor beta-1 (TGFB1) may influence asthma by modulating allergic airway inflammation and airway remodeling. The role of single nucleotide…”
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Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene by Duerr, Richard H, Taylor, Kent D, Brant, Steven R, Rioux, John D, Silverberg, Mark S, Daly, Mark J, Steinhart, A. Hillary, Abraham, Clara, Regueiro, Miguel, Griffiths, Anne, Dassopoulos, Themistocles, Bitton, Alain, Yang, Huiying, Targan, Stephan, Datta, Lisa Wu, Kistner, Emily O, Schumm, L. Philip, Lee, Annette T, Gregersen, Peter K, Barmada, M. Michael, Rotter, Jerome I, Nicolae, Dan L, Cho, Judy H

“…The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic disorders that cause abdominal pain, diarrhea, and gastrointestinal…”
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Interpretation of digital mammograms: comparison of speed and accuracy of soft-copy versus printed-film display by Pisano, Etta D, Cole, Elodia B, Kistner, Emily O, Muller, Keith E, Hemminger, Bradley M, Brown, Mary L, Johnston, R Eugene, Kuzmiak, Cherie M, Braeuning, M Patricia, Freimanis, Rita I, Soo, Mary Scott, Baker, J A, Walsh, Ruth

“…To compare the speed and accuracy of the interpretations of digital mammograms by radiologists by using printed-film versus soft-copy display. After being…”
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Evaluation of Genetic Variation Contributing to Differences in Gene Expression between Populations by Zhang, Wei, Duan, Shiwei, Kistner, Emily O., Bleibel, Wasim K., Huang, R. Stephanie, Clark, Tyson A., Chen, Tina X., Schweitzer, Anthony C., Blume, John E., Cox, Nancy J., Dolan, M. Eileen

“…Gene expression is a complex quantitative trait partially regulated by genetic variation in DNA sequence. Population differences in gene expression could…”
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Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity by Hartford, Christine M., Duan, Shiwei, Delaney, Shannon M., Mi, Shuangli, Kistner, Emily O., Lamba, Jatinder K., Huang, R. Stephanie, Dolan, M. Eileen

“…Cytarabine arabinoside (ara-C) is an antimetabolite used to treat hematologic malignancies. Resistance is a common reason for treatment failure with adverse…”
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PACdb: a database for cell-based pharmacogenomics by Gamazon, Eric R, Duan, Shiwei, Zhang, Wei, Huang, Rong Stephanie, Kistner, Emily O, Dolan, Mary Eileen, Cox, Nancy J

“…We have developed Pharmacogenomics And Cell database (PACdb), a results database that makes available relationships between single nucleotide polymorphisms,…”
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Platinum Sensitivity-Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients by HUANG, R. Stephanie, JOHNATTY, Sharon E, SHUANGLI MI, O'DONNELL, Peter H, FRAIMAN, Yarden S, DAS, Soma, COX, Nancy J, YI LU, MACGREGOR, Stuart, GOODE, Ellen L, VIERKANT, Robert A, FRIDLEY, Brooke L, GAMAZON, Eric R, HOGDALL, Estrid, KJAER, Susanne K, JENSEN, Allan, MOYSICH, Kirsten B, GRASELA, Matthew, ODUNSI, Kunle, BROWN, Robert, PAUL, Jim, LAMBRECHTS, Diether, DESPIERRE, Evelyn, HAE KYUNG IM, VERGOTE, Ignace, GROSS, Jenny, KARLAN, Beth Y, DEFAZIO, Anna, CHENEVIX-TRENCH, Georgia, DOLAN, M. Eileen, ZILIAK, Dana, SHIWEI DUAN, WEI ZHANG, KISTNER, Emily O, PEIXIAN CHEN, BEESLEY, Jonathan

“…Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy. We conducted genome-wide…”
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Identification of genomic regions contributing to etoposide-induced cytotoxicity by Bleibel, Wasim K, Duan, Shiwei, Huang, R. Stephanie, Kistner, Emily O, Shukla, Sunita J, Wu, Xiaolin, Badner, Judith A, Dolan, M. Eileen

“…Etoposide is routinely used in combination-based chemotherapy for testicular cancer and small-cell lung cancer; however, myelosuppression, therapy-related…”
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Using Cases and Parents to Study Multiplicative Gene-by-Environment Interaction by Kistner, Emily O., Shi, Min, Weinberg, Clarice R.

“…With case-parent triads, one can estimate genotype relative risks by measuring the apparent overtransmission of susceptibility genotypes from parents to…”
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Genetic polymorphisms in arginase I and II and childhood asthma and atopy by Li, Huiling, Romieu, Isabelle, Sienra-Monge, Juan-Jose, Ramirez-Aguilar, Matiana, Estela del Rio-Navarro, Blanca, Kistner, Emily O., Gjessing, Håkon K., Lara-Sanchez, Irma del Carmen, Chiu, Grace Y., London, Stephanie J.

“…A recent microarray study implicated arginase I ( ARG1) and arginase II ( ARG2) in mouse allergic asthma models and human asthma. To examine the association…”
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Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans by Huang, Rong Stephanie, Duan, Shiwei, Kistner, Emily O, Zhang, Wei, Bleibel, Wasim K, Cox, Nancy J, Dolan, M Eileen

“…OBJECTIVESThe very important pharmacogenes (VIPs) were selected by Pharmacogenetic Research Network (National Institutes of Health-PGRN) owing to their…”
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