Search Results - "KISSENPFENNIG, Adrien"

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS by Jackson, Megan V., Morrison, Thomas J., Doherty, Declan F., McAuley, Daniel F., Matthay, Michael A., Kissenpfennig, Adrien, O'Kane, Cecilia M., Krasnodembskaya, Anna D.

“…Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in preclinical models of Acute Respiratory Distress Syndrome (ARDS) and…”
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Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration by Sambasivan, Ramkumar, Yao, Roseline, Kissenpfennig, Adrien, Van Wittenberghe, Laetitia, Paldi, Andràs, Gayraud-Morel, Barbara, Guenou, Hind, Malissen, Bernard, Tajbakhsh, Shahragim, Galy, Anne

“…Distinct cell populations with regenerative capacity have been reported to contribute to myofibres after skeletal muscle injury, including non-satellite cells…”
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In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells by Calderon-Gonzalez, Ricardo, Dumigan, Amy, Sá-Pessoa, Joana, Kissenpfennig, Adrien, Bengoechea, José A

“…In vivo single-cell approaches have transformed our understanding of the immune populations in tissues. Mass cytometry (CyTOF), that combines the resolution of…”
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CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells by Henri, Sandrine, Poulin, Lionel Franz, Tamoutounour, Samira, Ardouin, Laurence, Guilliams, Martin, de Bovis, Béatrice, Devilard, Elisabeth, Viret, Christophe, Azukizawa, Hiroaki, Kissenpfennig, Adrien, Malissen, Bernard

“…Recent studies have challenged the view that Langerhans cells (LCs) constitute the exclusive antigen-presenting cells of the skin and suggest that the dermal…”
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Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network by Chorro, Laurent, Sarde, Aurélien, Li, Mei, Woollard, Kevin J, Chambon, Pierre, Malissen, Bernard, Kissenpfennig, Adrien, Barbaroux, Jean-Baptiste, Groves, Richard, Geissmann, Frédéric

“…Most tissues develop from stem cells and precursors that undergo differentiation as their proliferative potential decreases. Mature differentiated cells rarely…”
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Identification of a novel population of Langerin+ dendritic cells by Bursch, Laura S, Wang, Liangchun, Igyarto, Botond, Kissenpfennig, Adrien, Malissen, Bernard, Kaplan, Daniel H, Hogquist, Kristin A

“…Langerhans cells (LCs) are antigen-presenting cells that reside in the epidermis of the skin and traffic to lymph nodes (LNs). The general role of these cells…”
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Deletion of Socs3 in LysM + cells and Cx3cr1 resulted in age-dependent development of retinal microgliopathy by Du, Xuan, Penalva, Rosana, Little, Karis, Kissenpfennig, Adrien, Chen, Mei, Xu, Heping

“…We generated a mouse model of primary microglial dysfunction by deleting two negative immune regulatory genes, Cx3cr1 and Socs3 (in LysM cells). This study…”
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Btk regulates macrophage polarization in response to lipopolysaccharide by Ní Gabhann, Joan, Hams, Emily, Smith, Siobhán, Wynne, Claire, Byrne, Jennifer C, Brennan, Kiva, Spence, Shaun, Kissenpfennig, Adrien, Johnston, James A, Fallon, Padraic G, Jefferies, Caroline A

“…Bacterial Lipopolysaccharide (LPS) is a strong inducer of inflammation and does so by inducing polarization of macrophages to the classic inflammatory M1…”
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Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state by Ginhoux, Florent, Collin, Matthew P, Bogunovic, Milena, Abel, Michal, Leboeuf, Marylene, Helft, Julie, Ochando, Jordi, Kissenpfennig, Adrien, Malissen, Bernard, Grisotto, Marcos, Snoeck, Hans, Randolph, Gwendalyn, Merad, Miriam

“…Langerin is a C-type lectin receptor that recognizes glycosylated patterns on pathogens. Langerin is used to identify human and mouse epidermal Langerhans…”
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FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer by Annett, Stephanie, Moore, Gillian, Short, Amy, Marshall, Andrea, McCrudden, Cian, Yakkundi, Anita, Das, Sudipto, McCluggage, W. Glenn, Nelson, Laura, Harley, Ian, Moustafa, Nermeen, Kennedy, Catherine J., deFazio, Anna, Brand, Alison, Sharma, Raghwa, Brennan, Donal, O’Toole, Sharon, O’Leary, John, Bates, Mark, O’Riain, Ciarán, O’Connor, Darran, Furlong, Fiona, McCarthy, Helen, Kissenpfennig, Adrien, McClements, Lana, Robson, Tracy

“…Background ALM201 is a therapeutic peptide derived from FKBPL that has previously undergone preclinical and clinical development for oncology indications and…”
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STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes by Chen, Mei, Obasanmi, Gideon, Armstrong, David, Lavery, Nuala-Jane, Kissenpfennig, Adrien, Lois, Noemi, Xu, Heping

“…Leukostasis is a key patho-physiological event responsible for capillary occlusion in diabetic retinopathy. Circulating monocytes are the main cell type…”
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In vivo single‐cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection by Dumigan, Amy, Cappa, Oisin, Morris, Brenda, Sá Pessoa, Joana, Calderon‐Gonzalez, Ricardo, Mills, Grant, Lancaster, Rebecca, Simpson, David, Kissenpfennig, Adrien, Bengoechea, Jose A

“…The strategies deployed by antibiotic‐resistant bacteria to counteract host defences are poorly understood. Here, we elucidate a novel host–pathogen…”
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Elucidation of the RamA regulon in Klebsiella pneumoniae reveals a role in LPS regulation by De Majumdar, Shyamasree, Yu, Jing, Fookes, Maria, McAteer, Sean P, Llobet, Enrique, Finn, Sarah, Spence, Shaun, Monahan, Avril, Monaghan, Avril, Kissenpfennig, Adrien, Ingram, Rebecca J, Bengoechea, José, Gally, David L, Fanning, Séamus, Elborn, Joseph S, Schneiders, Thamarai

“…Klebsiella pneumoniae is a significant human pathogen, in part due to high rates of multidrug resistance. RamA is an intrinsic regulator in K. pneumoniae…”
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Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis by Chen, Mei, Zhao, Jiawu, Ali, Imran H.A., Marry, Stephen, Augustine, Josy, Bhuckory, Mohajeet, Lynch, Aisling, Kissenpfennig, Adrien, Xu, Heping

“…The suppressor of cytokine signaling protein 3 (SOCS3) critically controls immune cell activation, although its role in macrophage polarization and function…”
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Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions by Wang, Liangchun, Bursch, Laura S, Kissenpfennig, Adrien, Malissen, Bernard, Jameson, Stephen C, Hogquist, Kristin A

“…There are conflicting data in the literature regarding the role of epidermal Langerhans cells (LC) in promoting skin immune responses. On one hand, LC can be…”
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FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis by Yakkundi, Anita, Bennett, Rachel, Hernández-Negrete, Ivette, Delalande, Jean-Marie, Hanna, Mary, Lyubomska, Oksana, Arthur, Kenneth, Short, Amy, McKeen, Hayley, Nelson, Laura, McCrudden, Cian M, McNally, Ross, McClements, Lana, McCarthy, Helen O, Burns, Alan J, Bicknell, Roy, Kissenpfennig, Adrien, Robson, Tracy

“…The antitumor effects of FK506-binding protein like (FKBPL) and its extracellular role in angiogenesis are well characterized; however, its role in…”
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Laser-engineered dissolving microneedle arrays for protein delivery: potential for enhanced intradermal vaccination by McCrudden, Maelíosa T. C., Torrisi, Barbara M., Al-Zahrani, Sharifah, McCrudden, Cian M., Zaric, Marija, Scott, Christopher J., Kissenpfennig, Adrien, McCarthy, Helen O., Donnelly, Ryan F.

“…Objectives We aimed to highlight the utility of novel dissolving microneedle (MN)‐based delivery systems for enhanced transdermal protein delivery. Vaccination…”
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Langerhans cells promote early germinal center formation in response to Leishmania‐derived cutaneous antigens by Zimara, Nicole, Florian, Christian, Schmid, Maximilian, Malissen, Bernard, Kissenpfennig, Adrien, Männel, Daniela N., Edinger, Matthias, Hutchinson, James A., Hoffmann, Petra, Ritter, Uwe

“…Efficient formation of early GCs depends on the close interaction between GC B cells and antigen‐primed CD4+ follicular helper T cells (TFH). A tight and…”
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Structural Bases for the Affinity-Driven Selection of a Public TCR against a Dominant Human Cytomegalovirus Epitope by Gras, Stephanie, Saulquin, Xavier, Reiser, Jean-Baptiste, Debeaupuis, Emilie, Echasserieau, Klara, Kissenpfennig, Adrien, Legoux, Francois, Chouquet, Anne, Le Gorrec, Madalen, Machillot, Paul, Neveu, Berangere, Thielens, Nicole, Malissen, Bernard, Bonneville, Marc, Housset, Dominique

“…Protective T cell responses elicited along chronic human CMV (HCMV) infections are sometimes dominated by CD8 T cell clones bearing highly related or identical…”
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Langerhans cells are critical in the development of atopic dermatitis‐like inflammation and symptoms in mice by Elentner, Andreas, Finke, Daniela, Schmuth, Matthias, Chappaz, Stéphane, Ebner, Susanne, Malissen, Bernard, Kissenpfennig, Adrien, Romani, Nikolaus, Dubrac, Sandrine

“…Genetic or vitamin D3‐induced overexpression of thymic stromal lymphopoietin (TSLP) by keratinocytes results in an atopic dermatitis (AD)‐like inflammatory…”
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