Search Results - "KISSEBAH, A. H"

INSIG1 influences obesity-related hypertriglyceridemia in humans by Smith, E.M., Zhang, Y., Baye, T. M, Gawrieh, S., Cole, R., Blangero, J., Carless, M.A., Curran, J.E., Dyer, T.D., Abraham, L.J., Moses, E.K., Kissebah, A.H., Martin, L.J., Olivier, M.

“…In our analysis of a quantitative trait locus (QTL) for plasma triglyceride (TG) levels [logarithm of odds (LOD) = 3.7] on human chromosome 7q36, we examined…”
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Comparison of linkage disequilibrium patterns between the HapMap CEPH samples and a family-based cohort of Northern European descent by Smith, E.M., Wang, X., Littrell, J., Eckert, J., Cole, R., Kissebah, A.H., Olivier, M.

“…The International HapMap Consortium has determined the linkage disequilibrium (LD) patterns of four major human populations. The aim of our investigation was…”
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Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels by Zhang, Y, Smith, E M, Baye, T M, Eckert, J V, Abraham, L J, Moses, E K, Kissebah, A H, Martin, L J, Olivier, M

“…Neurotransmitters such as serotonin (5-hydroxytryptamine, 5-HT) work closely with leptin and insulin to fine-tune the metabolic and neuroendocrine responses to…”
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Insulin resistance in visceral obesity by Kissebah, A H

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Effects of free fatty acids and glucose on splanchnic insulin dynamics by Hennes, M. M., Dua, A., Kissebah, A. H.

“…Effects of free fatty acids and glucose on splanchnic insulin dynamics. M M Hennes , A Dua and A H Kissebah Department of Medicine, Medical College of…”
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Adiposity, fat distribution, and cardiovascular risk by Peiris, A N, Sothmann, M S, Hoffmann, R G, Hennes, M I, Wilson, C R, Gustafson, A B, Kissebah, A H

“…To determine the relative importance of adiposity and fat distribution to cardiovascular risk profile. A cross-sectional study. Clinical research center funded…”
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Genotype-by-smoking interaction for leptin levels in the Metabolic Risk Complications of Obesity Genes project by Martin, L.J, Kissebah, A.H, Soonenberg, G.E, Blangero, J, Comuzzie, A.G

“…RATIONALE: Recently, we identified a genotype-by-smoking status interaction with serum leptin levels in a sample of Mexican Americans. However, it is unknown…”
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Plasma leptin and insulin levels in weight-reduced obese women with normal body mass index: relationships with body composition and insulin by GUVEN, S, EL-BERSHAWI, A, SONNENBERG, G. E, WILSON, C. R, HOMNANN, R. G, KRAKOWER, G. R, KISSEBAH, A. H

“…Plasma leptin and insulin levels in weight-reduced obese women with normal body mass index: relationships with body composition and insulin. S Guven , A…”
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Intra-abdominal fat: is it a major factor in developing diabetes and coronary artery disease? by Kissebah, Ahmed H.

“…Abdominal obesity has emerged as a strong and independent predictor for non-insulin dependent diabetes mellitus (NIDDM). Adiposity located centrally in the…”
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Leptin: a significant indicator of total body fat but not of visceral fat and insulin insensitivity in African-American women by Dua, A., Hennes, M. I., Hoffmann, R. G., Maas, D. L., Krakower, G. R., Sonnenberg, G. E., Kissebah, A. H.

“…Leptin: a significant indicator of total body fat but not of visceral fat and insulin insensitivity in African-American women. A Dua , M I Hennes , R G…”
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Splanchnic insulin metabolism in obesity: influence of body fat distribution by PEIRIS, A. N, MUELLER, R. A, SMITH, G. A, STRUVE, M. F, KISSEBAH, A. H

“…The effects of obesity and body fat distribution on splanchnic insulin metabolism and the relationship to peripheral insulin sensitivity were assessed in 6…”
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QTL‐based association analyses reveal novel genes influencing pleiotropy of metabolic syndrome (MetS) by Zhang, Y., Kent, J.W., Olivier, M., Ali, O., Broeckel, U., Abdou, R.M., Dyer, T.D., Comuzzie, A., Curran, J.E., Carless, M.A., Rainwater, D.L., Göring, H.H.H., Blangero, J., Kissebah, A.H.

“…Objective: Metabolic Syndrome (MetS) is a phenotype cluster predisposing to type 2 diabetes and cardiovascular disease. We conducted a study to elucidate the…”
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Health risks of obesity by Kissebah, A H, Freedman, D S, Peiris, A N

“…Evidence implicating obesity as a risk-factor disease is critically reviewed. Possible reasons for the many conflicting findings are addressed. The…”
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Relationship between skeletal muscle insulin resistance, insulin-mediated glucose disposal, and insulin binding: effects of obesity and body fat topography by EVANS, D. J, MURRAY, R, KISSEBAH, A. H

“…Skeletal muscle sensitivity and responsiveness to insulin and their relationship to overall glucose disposal and insulin binding were determined in 89…”
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Body fat distribution and male/female differences in lipids and lipoproteins by FREEDMAN, D. S, JACOBSEN, S. J, BARBORIAK, J. J, SOBOCINSKI, K. A, ANDERSON, A. J, KISSEBAH, A. H, SASSE, E. A, GRUCHOW, H. W

“…The role of body fat distribution, as assessed by the ratio of waist-to-hip circumferences (WHR), in statistically explaining differences in levels of…”
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Insulin-Resistant Lipolysis in Abdominally Obese Hypertensive Individuals: Role of the Renin-Angiotensin System by Hennes, Magda M.I, O'Shaughnessy, Irene M, Kelly, Thomas M, LaBelle, Patrice, Egan, Brent M, Kissebah, Ahmed H

“…Resistance to the capacity of insulin to suppress lipolysis may be an important link in the association between abdominal obesity and hypertension…”
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Quantitative Trait Loci on Chromosomes 3 and 17 Influence Phenotypes of the Metabolic Syndrome by Kissebah, A H, Sonnenberg, G E, Myklebust, J, Goldstein, M, Broman, K, James, R G, Marks, J A, Krakower, G R, Jacob, H J, Weber, J, Martin, L, Blangero, J, Comuzzie, A G

“…Recent research has emphasized the importance of the metabolic cluster, which includes glucose intolerance, dyslipidemia, and high blood pressure, as a strong…”
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Insulin sensitivity and antiandrogenic therapy in women with polycystic ovary syndrome by Diamanti-Kandarakis, Evanthia, Mitrakou, Asimina, Hennes, Magda M.I., Platanissiotis, Dimitris, Kaklas, Nicholas, Spina, Jovanna, Georgiadou, Elli, Hoffmann, Raymond G., Kissebah, Ahmed H., Raptis, Sotos

“…Polycystic ovary (PCO) syndrome is strongly associated with insulin resistance and the accompanying adverse metabolic profile. To distinguish the mechanisms of…”
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Regional adiposity and morbidity by Kissebah, A H, Krakower, G R

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Obesity Hypertension Is Related More to Insulin's Fatty Acid Than Glucose Action by Egan, Brent M, Hennes, Magda M.I, Stepniakowski, Konrad T, O'Shaughnessy, Irene M, Kissebah, Ahmed H, Goodfriend, Theodore L

“…Although resistance to insulin-mediated glucose disposal has emerged as a link between abdominal obesity and hypertension, abnormalities of nonesterified fatty…”
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