Search Results - "KISHIMOTO, TAKEO"
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MPF-based meiotic cell cycle control: Half a century of lessons from starfish oocytes
Published in Proceedings of the Japan Academy, Series B (2018)“…In metazoans that undergo sexual reproduction, genomic inheritance is ensured by two distinct types of cell cycle, mitosis and meiosis. Mitosis maintains the…”
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SGK phosphorylates Cdc25 and Myt1 to trigger cyclin B-Cdk1 activation at the meiotic G2/M transition
Published in The Journal of cell biology (04-11-2019)“…The kinase cyclin B-Cdk1 complex is a master regulator of M-phase in both mitosis and meiosis. At the G2/M transition, cyclin B-Cdk1 activation is initiated by…”
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A primer on meiotic resumption in starfish oocytes: The proposed signaling pathway triggered by maturation-inducing hormone
Published in Molecular reproduction and development (01-10-2011)“…This short review updates the maturation‐inducing hormonal signaling in starfish oocytes. In this system, the activation of cyclin B‐Cdc2 kinase (Cdk1) that…”
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Regulators specifying cell fate activate cell cycle regulator genes to determine cell numbers in ascidian larval tissues
Published in Development (Cambridge) (15-11-2022)“…In animal development, most cell types stop dividing before terminal differentiation; thus, cell cycle control is tightly linked to cell differentiation…”
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Identification of jellyfish neuropeptides that act directly as oocyte maturation-inducing hormones
Published in Development (Cambridge) (22-01-2018)“…Oocyte meiotic maturation is crucial for sexually reproducing animals, and its core cytoplasmic regulators are highly conserved between species. By contrast,…”
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Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor
Published in Nature communications (11-09-2012)“…Maturation/M-phase-promoting factor is the universal inducer of M-phase in eukaryotic cells. It is currently accepted that M-phase-promoting factor is…”
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SGK regulates pH increase and cyclin B-Cdk1 activation to resume meiosis in starfish ovarian oocytes
Published in The Journal of cell biology (04-11-2019)“…Tight regulation of intracellular pH (pH ) is essential for biological processes. Fully grown oocytes, having a large nucleus called the germinal vesicle,…”
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The Starfish Asterina pectinifera: Collection and Maintenance of Adults and Rearing and Metamorphosis of Larvae
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Here we describe methods for (a) collecting starfish during their breeding period; (b) maintaining adults with fully grown gonads in laboratory aquaria; (c)…”
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Cyclin B-Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase-independent mechanism
Published in The Journal of cell biology (17-03-2014)“…Entry into M phase is governed by cyclin B-Cdk1, which undergoes both an initial activation and subsequent autoregulatory activation. A key part of the…”
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Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs
Published in Nature (26-04-2007)“…Until fertilization, the meiotic cell cycle of vertebrate eggs is arrested at metaphase of meiosis II by a cytoplasmic activity termed cytostatic factor (CSF),…”
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Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis
Published in Nature (20-09-2007)“…At fertilization, an increase of cytosolic calcium ions (Ca2+) triggers various activation responses in animal eggs. In vertebrates, these responses include…”
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Two novel competing pathways establish the threshold for cyclin B-Cdk1 activation at the meiotic G2/M transition
Published in Journal of cell science (01-01-2016)“…Extracellular ligand stimuli control biological phenomena. Cells distinguish physiological stimuli from weak noise stimuli by establishing a…”
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The Mos-MAPK pathway regulates Diaphanous-related formin activity to drive cleavage furrow closure during polar body emission in starfish oocytes
Published in Journal of cell science (01-01-2013)“…Maintenance of spindle attachment to the cortex and formation of the cleavage furrow around the protruded spindle are essential for polar body emission (PBE)…”
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Antibody inhibition of protein activity in starfish oocytes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2014)“…Antibodies are widely utilized in cell and molecule biology for immunoblots, immunostaining, immunoprecipitation, immunoaffinity purification, and immunoassay…”
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single starfish Aurora kinase performs the combined functions of Aurora-A and Aurora-B in human cells
Published in Journal of cell science (15-11-2010)“…Aurora, an essential mitotic kinase, is highly conserved during evolution. Most vertebrates have at least two Aurora kinases, Aurora-A and Aurora-B, which have…”
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Calpain-dependent Proteolytic Cleavage of the p35 Cyclin-dependent Kinase 5 Activator to p25
Published in The Journal of biological chemistry (02-06-2000)“…Cyclin-dependent kinase 5 (CDK5) is a unique CDK, the activity of which can be detected in postmitotic neurons. To date, CDK5 purified from mammalian brains…”
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Start of the embryonic cell cycle is dually locked in unfertilized starfish eggs
Published in Development (Cambridge) (15-05-2009)“…A key event in the oocyte-to-embryo transition is the start of the embryonic mitotic cell cycle. Prior to this start, the cell cycle in oocytes is generally…”
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Entry into mitosis: a solution to the decades-long enigma of MPF
Published in Chromosoma (01-12-2015)“…Maturation or M phase-promoting factor (MPF) is the universal inducer of M phase common to eukaryotic cells. MPF was originally defined as a transferable…”
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Cyclin B-Cdk1 Controls Pronuclear Union in Interphase
Published in Current biology (09-09-2008)“…In sexual reproduction, the union of the male and female pronuclei occurs in fertilized eggs to mix genetic materials derived from both parents, thereby…”
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Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation
Published in Nucleic acids research (01-12-2012)“…Gene downregulation by antisense morpholino oligonucleotides (MOs) is achieved by either hybridization around the translation initiation codon or by targeting…”
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