Search Results - "KISHIHARA, Kenji"

IL-12 protects from psoriasiform skin inflammation by Kulig, Paulina, Musiol, Stephanie, Freiberger, Sandra Nicole, Schreiner, Bettina, Gyülveszi, Gabor, Russo, Giancarlo, Pantelyushin, Stanislav, Kishihara, Kenji, Alessandrini, Francesca, Kündig, Thomas, Sallusto, Federica, Hofbauer, Günther F.L., Haak, Stefan, Becher, Burkhard

“…Neutralization of the common p40-subunit of IL-12/23 in psoriasis patients has led to a breakthrough in the management of moderate to severe disease. Aside…”
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Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung by Okamoto Yoshida, Yuko, Umemura, Masayuki, Yahagi, Ayano, O'Brien, Rebecca L, Ikuta, Koichi, Kishihara, Kenji, Hara, Hiromitsu, Nakae, Susumu, Iwakura, Yoichiro, Matsuzaki, Goro

“…Granulomas play an essential role in the sequestration and killing of mycobacteria in the lung; however, the mechanisms of their development and maturation are…”
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Notch signaling drives IL-22 secretion in CD4⁺ T cells by stimulating the aryl hydrocarbon receptor by Alam, Muhammad Shamsul, Maekawa, Yoichi, Kitamura, Akiko, Tanigaki, Kenji, Yoshimoto, Takayuki, Kishihara, Kenji, Yasutomo, Koji

“…CD4⁺ helper T (Th) cells differentiate toward distinct effector cell lineages characterized by their distinct cytokine expression patterns and functions…”
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Age-related functional decline of human B cells by Fujiki, Tsukasa, Matsumoto, Shin-Ei, Kishihara, Kenji, Katakura, Yoshinori

“…This study aimed to investigate the changes in B cell functional decline and antigen sensitization with aging using two Epstein Barr virus (EBV)-immortalized…”
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Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines by Uto, Takuhiro, Sakamoto, Ayana, Tung, Nguyen Huu, Fujiki, Tsukasa, Kishihara, Kenji, Oiso, Shigeru, Kariyazono, Hiroko, Morinaga, Osamu, Shoyama, Yukihiro

“…Eriobotrya japonica leaf is a traditional herbal medicine that contains numerous triterpenes, which have various pharmacological properties. In this study, we…”
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Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death by Tsuruya, Kazuhiko, Ninomiya, Toshiharu, Tokumoto, Masanori, Hirakawa, Makoto, Masutani, Kohsuke, Taniguchi, Masatomo, Fukuda, Kyoichi, Kanai, Hidetoshi, Kishihara, Kenji, Hirakata, Hideki, Iida, Mitsuo

“…Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death. Tumor necrosis factor (TNF) receptor family…”
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Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction by Kijima, Mika, Yamaguchi, Takeshi, Ishifune, Chieko, Maekawa, Yoichi, Koyanagi, Akemi, Yagita, Hideo, Chiba, Shigeru, Kishihara, Kenji, Shimada, Mitsuo, Yasutomo, Koji

“…Natural killer (NK) cells regulate various immune responses by exerting cytotoxic activity or secreting cytokines. The interaction of NK cells with dendritic…”
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Differentiation of CD11c⁺CX₃CR1⁺ cells in the small intestine requires Notch signaling by Ishifune, Chieko, Maruyama, Satoshi, Sasaki, Yuki, Yagita, Hideo, Hozumi, Katsuto, Tomita, Taisuke, Kishihara, Kenji, Yasutomo, Koji

“…The gastrointestinal tract comes into direct contact with environmental agents, including bacteria, viruses, and foods. Intestine-specific subsets of immune…”
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Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice by Lian, Gaojian, Arimochi, Hideki, Kitamura, Akiko, Nishida, Jun, Li, Shigen, Kishihara, Kenji, Maekawa, Yoichi, Yasutomo, Koji

“…The interplay of CD4(+) and CD8(+) T cells targeting autoantigens is responsible for the progression of a number of autoimmune diseases, including type 1…”
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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection by Pfeffer, K, Matsuyama, T, Kündig, T M, Wakeham, A, Kishihara, K, Shahinian, A, Wiegmann, K, Ohashi, P S, Krönke, M, Mak, T W

“…The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd (TNFRp55) and 75 kd (TNFRp75)…”
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Intraepithelial γδ T Cells May Bridge a Gap between Innate Immunity and Acquired Immunity to Herpes Simplex Virus Type 2 by NISHIMURA, Hitoshi, YAJIMA, Toshiki, KAGIMOTO, Yoshiko, OHATA, Mutsuhiro, WATASE, Taketo, KISHIHARA, Kenji, GOSHIMA, Fumi, NISHIYAMA, Yukihiro, YOSHIKAI, Yasunobu

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45 by Cyster, Jason G, Healy, James I, Kishihara, Kenji, Mak, Tak W, Thomas, Matthew L, Goodnow, Christopher C

“…Elimination of self-reactive B cells must be balanced against the need for B-cell diversity for antibody responses to pathogens. To analyse factors that…”
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Resident Vδ1+ γδ T Cells Control Early Infiltration of Neutrophils after Escherichia coli Infection via IL-17 Production by Shibata, Kensuke, Yamada, Hisakata, Hara, Hiromitsu, Kishihara, Kenji, Yoshikai, Yasunobu

“…Abstract Neutrophils infiltrate the site of infection and play critical roles in host defense, especially against extracellular bacteria. In the present study,…”
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Crucial Fas–Fas ligand interaction in spontaneous acceptance of hepatic allografts in mice by Uchiyama, Hideaki, Kishihara, Kenji, Minagawa, Ryosuke, Hashimoto, Koji, Sugimachi, Keizo, Nomoto, Kikuo

“…Summary The Fas/Fas ligand (FasL) system plays important roles in the immune system, including host immunoregulation and cytotoxicity. In this study, we…”
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Donor-specific tolerance induced by simultaneous allogeneic islet transplantation with CD4+CD25+ T-cells into hepatic parenchyma in mice by Ikemoto, Tetsuya, Tashiro, Seiki, Yasutomo, Koji, Kishihara, Kenji, Kurita, Nobuhiro, Miyake, Hidenori

“…Background. The allogeneic islets transplantation is an ideal therapeutic strategy for patients with diabetes mellitus. However, it has been difficult to…”
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The crucial role of granulocytes in the early host defense against Strongyloides ratti infection in mice by WATANABE, K, NODA, K, HAMANO, S, KOGA, M, KISHIHARA, K, NOMOTO, K, TADA, I

“…The involvement of granulocytes in the host early defense against the nematode, Strongyloides ratti, was studied. It was confirmed that granulocytes were…”
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Differential Requirements of CD45 Protein Tyrosine Phosphatase for Cytolytic Activities and Intrathymic and Extrathymic Development of Intestinal Intraepithelial Lymphocytes by Yada, Shinichiro, Kishihara, Kenji, Kong, Young-Yun, Nomoto, Kikuo

“…CD45 is a transmembrane protein tyrosine phosphatase essential for Ag receptor-mediated signaling in both T and B cells. In this study we investigated roles of…”
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Escape of malaria parasites from host immunity requires CD4 + CD25 + regulatory T cells by Yasutomo, Koji, Hisaeda, Hajime, Maekawa, Yoichi, Iwakawa, Daiji, Okada, Hiroko, Himeno, Kunisuke, Kishihara, Kenji, Tsukumo, Shin-ichi

“…Infection with malaria parasites frequently induces total immune suppression, which makes it difficult for the host to maintain long-lasting immunity. Here we…”
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Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4 + T Cells by Maekawa, Yoichi, Tsukumo, Shin-ichi, Chiba, Shigeru, Hirai, Hisamaru, Hayashi, Yuki, Okada, Hiroko, Kishihara, Kenji, Yasutomo, Koji

“…Following activation by antigen, naive CD4 + T helper precursor cells execute distinct genetic programs that result in their differentiation toward the type 1…”
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Differentiation of CD11c+CX^sub 3^CR1+ cells in the small intestine requires Notch signaling by Ishifune, Chieko, Maruyama, Satoshi, Sasaki, Yuki, Yagita, Hideo, Hozumi, Katsuto, Tomita, Taisuke, Kishihara, Kenji, Yasutomo, Koji

“…The gastrointestinal tract comes into direct contact with environmental agents, including bacteria, viruses, and foods. Intestine-specific subsets of immune…”
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