Search Results - "KIRSH, M. M"
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Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
Published in BMC cancer (01-06-2023)“…Neuropeptide Y (NPY) is an abundant neurohormone in human breast carcinomas that acts on a class of G-protein coupled receptors, of which NPY1R and NPY5R are…”
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Structural Characterization of Fluorescent Proteins Using Tunable Femtosecond Stimulated Raman Spectroscopy
Published in International journal of molecular sciences (26-07-2023)“…The versatile functions of fluorescent proteins (FPs) as fluorescence biomarkers depend on their intrinsic chromophores interacting with the protein…”
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Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation
Published in The Journal of biological chemistry (01-03-2022)“…Neuropeptide Y (NPY) is an abundant neurohormone in the central and peripheral nervous system involved in feeding behavior, energy balance, nociception, and…”
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Nitrile Infrared Intensities Characterize Electric Fields and Hydrogen Bonding in Protic, Aprotic, and Protein Environments
Published in Journal of the American Chemical Society (04-05-2022)“…Nitriles are widely used vibrational probes; however, the interpretation of their IR frequencies is complicated by hydrogen bonding (H-bonding) in protic…”
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Critical Evaluation of Polarizable and Nonpolarizable Force Fields for Proteins Using Experimentally Derived Nitrile Electric Fields
Published in Journal of the American Chemical Society (13-03-2024)“…Molecular dynamics (MD) simulations are frequently carried out for proteins to investigate the role of electrostatics in their biological function. The choice…”
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Synthesis and Characterization of (pyNO−)2GaCl: A Redox-Active Gallium Complex
Published in Inorganics (01-06-2018)“…We report the synthesis of a gallium complex incorporating redox-active pyridyl nitroxide ligands. The (pyNO−)2GaCl complex was prepared in 85% yield via a…”
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Protein protic and aprotic interactions systematically mapped via IR spectroscopy and polarizable molecular dynamics
Published in Biophysical journal (10-02-2023)Get full text
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Private Equity and Urology: An Emerging Model for Independent Practice
Published in Urologic clinics of North America (01-05-2021)“…Independent urology practices are under increasing competitive pressure in a changing marketplace. By providing access to capital and business management…”
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Carbon-deuterium bonds as reporters of electric fields in solvent and protein environments
Published in Biophysical journal (10-02-2023)Get full text
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Relation of regional function, perfusion, and metabolism in patients with advanced coronary artery disease undergoing surgical revascularization
Published in Circulation (New York, N.Y.) (01-11-1994)“…Imaging of myocardial glucose metabolism using [18F]fluorodeoxyglucose (FDG) with positron emission tomography (PET) has been proposed for identification of…”
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Impaired left ventricular contractile function in patients with long-term mitral regurgitation and normal ejection fraction
Published in Journal of the American College of Cardiology (01-07-1993)“…Objectives. We tested the hypotheses that left ventricular chamber elastance would detect impaired contractile function in patients with long-term mitral…”
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Spheroids as a 3D Model of the Hypoxic Tumor Microenvironment
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Spheroids enable the study of tumors and tumor hypoxia using a more representative model of the physiological environment compared to 2D cell culture…”
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Intravenous Diltiazem and Acute Renal Failure After Cardiac Operations
Published in The Annals of thoracic surgery (01-05-1998)“…Background. Perioperative administration of intravenous diltiazem to patients undergoing cardiac procedures has been shown to decrease the incidence of…”
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Descending necrotizing mediastinitis: Transcervical drainage is not enough
Published in The Annals of thoracic surgery (01-05-1990)“…One of the most lethal forms of mediastinitis is descending necrotizing mediastinitis, in which infection arising from the oropharynx spreads to the…”
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2014-2016: How far has LUGPA come?
Published in Reviews in urology (2016)Get full text
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The Cost of Prostate Biopsies and their Complications: A Summary of Data on All Medicare Fee-for-Service Patients over 2 Years
Published in Urology practice (01-03-2020)“…We define the cost of a contemporary prostate biopsy and the rate and incremental impact of complications on costs. A retrospective analysis of all Medicare…”
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Outcome of men with ischemic cardiomyopathy, asymptomatic nonsustained ventricular tachycardia, and negative electrophysiologic studies
Published in The American journal of cardiology (2000)“…The natural history of patients with ischemic cardiomyopathy, asymptomatic nonsustained ventricular tachycardia, and negative electrophysiologic studies was…”
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Superiority of controlled surgical reperfusion versus percutaneous transluminal coronary angioplasty in acute coronary occlusion
Published in The Journal of thoracic and cardiovascular surgery (01-05-1993)“…Although percutaneous transluminal coronary angioplasty is successful in more than 90% of patients after acute coronary occlusion, overall mortality remains…”
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Implementation of a Centralized, Cost-effective Call Center in a Large Urology Community Practice
Published in Reviews in urology (01-01-2020)“…Call centers provide front-line care and service to patients. This study compared call-answering efficiency and costs between the implementation of an…”
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