Search Results - "KIRSCHNER, Daniel L"
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Separation and sensitive detection of D-amino acids in biological matrices
Published in Journal of separation science (01-07-2009)“…The increase in our understanding of D-amino acid function and distribution in mammals is in many ways a result of the initial development of sensitive…”
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Journal Article -
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Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis, and glutamate efflux
Published in Journal of neurochemistry (01-07-2017)“…Cerebral ischemia/reperfusion (I/R) triggers a cascade of uncontrolled cellular processes that perturb cell homeostasis. The arctic ground squirrel (AGS), a…”
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Journal Article -
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Enantioseparation and Stacking of Cyanobenz[f]isoindole-Amino Acids by Reverse Polarity Capillary Electrophoresis and Sulfated β-Cyclodextrin
Published in Analytical chemistry (Washington) (15-01-2007)“…A capillary electrophoresis method with laser-induced fluorescence detection for the chiral separation of cyanobenz[f]isoindole (CBI) derivatives of amino…”
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Journal Article -
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Acidotoxicity via ASIC1a Mediates Cell Death during Oxygen Glucose Deprivation and Abolishes Excitotoxicity
Published in ACS chemical neuroscience (21-06-2017)“…Ischemic reperfusion (I/R) injury is associated with a complex and multifactorial cascade of events involving excitotoxicity, acidotoxicity, and ionic…”
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Journal Article -
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Separation of sulfoalkylated cyclodextrins with hydrophilic interaction liquid chromatography
Published in Journal of Chromatography A (05-11-2013)“…•HILIC is successfully applied to analyze mixtures of sulfopropylated cyclodextrins (CDs).•Charged states of sulfopropylated CDs from −1 to −14 are baseline…”
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Journal Article -
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Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation
Published in Journal of neuroscience research (01-09-2009)“…D‐serine and L‐glutamate play crucial roles in excitotoxicity through N‐methyl‐D‐aspartate receptor coactivation, but little is known about the temporal…”
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Journal Article -
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Nonaqueous synthesis of a selectively modified, highly anionic sulfopropyl ether derivative of cyclomaltoheptaose (β-cyclodextrin) in the presence of 18-crown-6
Published in Carbohydrate research (15-08-2005)“…[Display omitted] A highly anionic cyclomaltooligosaccharide (cyclodextrin, CD) derivative containing sulfopropyl functional groups on the primary face of the…”
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Bioanalytical development of charged cyclodextrin capillary electrokinetic chromatography and microperfusion sampling to study endogenous D-serine and L-glutamate efflux in brain
Published 01-01-2009“…A multitude of studies have revealed specific biological mechanisms that contribute to D-amino acid action and regulation in the mammalian central nervous…”
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Dissertation -
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Bioanalytical development of charged cyclodextrin capillary electrokinetic chromatography and microperfusion sampling to study endogenous D-serine and L-glutamate efflux in brain
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Dissertation