Search Results - "KIRSCH, C."

The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, Which Is Essential for Ribosome Biogenesis by Kirsch, Volker C., Orgler, Christina, Braig, Simone, Jeremias, Irmela, Auerbach, David, Müller, Rolf, Vollmar, Angelika M., Sieber, Stephan A.

“…Novel targets are needed for treatment of devastating diseases such as cancer. For decades, natural products have guided innovative therapies by addressing…”
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FICD activity and AMPylation remodelling modulate human neurogenesis by Kielkowski, Pavel, Buchsbaum, Isabel Y., Kirsch, Volker C., Bach, Nina C., Drukker, Micha, Cappello, Silvia, Sieber, Stephan A.

“…Posttranslational modification (PTM) of proteins represents an important cellular mechanism for controlling diverse functions such as signalling, localisation…”
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Social acceptance of green hydrogen in Germany: building trust through responsible innovation by Häußermann, Johann Jakob, Maier, Moritz J., Kirsch, Thea C., Kaiser, Simone, Schraudner, Martina

“…Background Social acceptance presents a major challenge for Germany’s transition to green energy. As a power-to-x technology, green hydrogen is set to become a…”
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A machine learning contest enhances automated freezing of gait detection and reveals time-of-day effects by Salomon, Amit, Gazit, Eran, Ginis, Pieter, Urazalinov, Baurzhan, Takoi, Hirokazu, Yamaguchi, Taiki, Goda, Shuhei, Lander, David, Lacombe, Julien, Sinha, Aditya Kumar, Nieuwboer, Alice, Kirsch, Leslie C., Holbrook, Ryan, Manor, Brad, Hausdorff, Jeffrey M.

“…Freezing of gait (FOG) is a debilitating problem that markedly impairs the mobility and independence of 38-65% of people with Parkinson’s disease. During a FOG…”
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Build-up dynamics of a self-mode-locked Thulium-doped fiber laser explored by dispersive Fourier transformation by Kirsch, Dennis C., Chernysheva, Maria

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Striatal FP-CIT uptake differs in the subtypes of early Parkinson's disease by Spiegel, J, Hellwig, D, Samnick, S, Jost, W, Möllers, M-O, Fassbender, K, Kirsch, C-M, Dillmann, U

“…In idiopathic Parkinson's disease (PD), a tremor-dominant type (TDT), an akinetic-rigid type (ART), and a mixed type (MT) are distinguished. We compared…”
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GPU Supported Simulation of Transition-edge Sensor Arrays by Lorenz, M, Kirsch, C, Merino-Alonso, P E, Peille, P, Dauser, T, Cucchetti, E, Smith, S J, Wilms, J

“…We present numerical simulations of full transition-edge sensor (TES) arrays utilizing graphical processing units (GPUs). With the support of GPUs, it is…”
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Gain-controlled broadband tuneability in self-mode-locked Thulium-doped fibre laser by Kirsch, Dennis C., Bednyakova, Anastasia, Varak, Petr, Honzatko, Pavel, Cadier, Benoit, Robin, Thierry, Fotiadi, Andrei, Peterka, Pavel, Chernysheva, Maria

“…Ensuring self-driven mode-locking and broadband wavelength tuneability in all-fibre-integrated femtosecond laser sources enables a new level of their…”
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The Performance of the Athena X-ray Integral Field Unit at Very High Count Rates by Peille, Philippe, Dauser, T., Kirsch, C., den Hartog, R., Cucchetti, E., Wilms, J., Barret, D., den Herder, J.-W., Piro, L.

“…The Athena X-ray Integral Field Unit (X-IFU) will operate at 90 mK a hexagonal matrix of 3840 Transition Edge Sensor pixels providing spatially resolved…”
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Time-Domain Modeling of TES Microcalorimeters Under AC Bias by Kirsch, C., Gottardi, L., Lorenz, M., Dauser, T., den Hartog, R., Jackson, B., Peille, P., Smith, S., Wilms, J.

“…We present developments in the simulation of transition-edge sensor (TES) microcalorimeters under AC bias for the purpose of detector studies. The presented…”
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Quantifying the Effect of Cosmic Ray Showers on the X-IFU Energy Resolution by Peille, P., Hartog, R. den, Miniussi, A., Stever, S., Bandler, S., Kirsch, C., Lorenz, M., Dauser, T., Wilms, J., Lotti, S., Gatti, F., Macculi, C., Jackson, B.

“…The X-ray Integral Field Unit (X-IFU) will operate an array of more than 3000 Transition Edge Sensor pixels at 90 mK with an unprecedented energy resolution of…”
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Simulation of Radiative Transfer Within X-ray Microcalorimeter Absorbers by Lorenz, M., Kirsch, C., Peille, P., Ballhausen, R., Fioretti, V., Lotti, S., Dauser, T., Wilms, J.

“…We present Monte Carlo simulations of radiative transfer within the absorbers of X-ray microcalorimeters, utilizing a numerical model for the photon…”
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Olfactory Anomalies in CHARGE Syndrome: Imaging Findings of a Potential Major Diagnostic Criterion by Blustajn, J, Kirsch, C.F.E, Panigrahy, A, Netchine, I

“…CHARGE syndrome is a genetic disorder resulting in the association of multiple congenital anomalies. Although a high prevalence of olfactory anomalies in…”
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The Athena X-IFU Instrument Simulator xifusim by Kirsch, C., Lorenz, M., Peille, P., Dauser, T., Ceballos, M. T., Cobo, B., Merino-Alonso, P. E., Cucchetti, E., Smith, S. J., Gottardi, L., Hartog, R. H. den, Miniussi, A., Durkin, M., Prêle, D., Wilms, J.

“…We present the instrument simulator xifusim developed for the X-ray Integral Field Unit X-IFU aboard the planned Athena mission. xifusim aims to be an accurate…”
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Statistical analysis of a self-starting linear Mamyshev oscillator with two symmetric Tm-doped fiber gain sections by Kirsch, Dennis C., Likhachev, Mikhail E., Aleshkina, Svetlana S., Yashkov, Mikhail V., Chernysheva, Maria

“…An innovative concept to achieve a self-starting, all-fibre and all-normal dispersion Mamyshev oscillator for the 1.9 μm wavelength domain is explored. A…”
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Randomized trial of rifabutin‐based triple therapy and high‐dose dual therapy for rescue treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin by MIEHLKE, S., HANSKY, K., SCHNEIDER‐BRACHERT, W., KIRSCH, C., MORGNER, A., MADISCH, A., KUHLISCH, E., BÄSTLEIN, E., JACOBS, E., BAYERDÖRFFER, E., LEHN, N., STOLTE, M.

“…Summary Background The clinical management of Helicobacter pylori infected patients who failed standard eradication therapies remains a challenge. Aim To…”
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Correction to: The Athena X-IFU Instrument Simulator xifusim by Kirsch, C., Lorenz, M., Peille, P., Dauser, T., Ceballos, M. T., Cobo, B., Merino-Alonso, P. E., Cucchetti, E., Smith, S. J., Gottardi, L., den Hartog, R. H., Miniussi, A., Durkin, M., Prêle, D., Wilms, J.

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FDG-PET, PET/CT and conventional nuclear medicine procedures in the evaluation of lung cancer: a systematic review by Hellwig, Dirk, Baum, Richrad P, Kirsch, Carl

“…Currently, the German and Austrian S3 guidelines on the evaluation and treatment of lung cancer are about to be published whereas the American Colleague of…”
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Conversations in accountability: Perspectives from three charities by Kirsch, David C

“…ObjectiveThe conversations in accountability were designed to gain an understanding of the use and changes to accountability in charities over time, including…”
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Crosstalk in an FDM Laboratory Setup and the Athena X-IFU End-to-End Simulator by den Hartog, R., Kirsch, C., de Vries, C., Akamatsu, H., Dauser, T., Peille, P., Cucchetti, E., Jackson, B., Bandler, S., Smith, S., Wilms, J.

“…The impact of various crosstalk mechanisms on the performance of the Athena X-IFU instrument has been assessed with detailed end-to-end simulations. For the…”
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