Search Results - "KIRKWOOD, K"
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Aggregatibacter actinomycetemcomitans, a potent immunoregulator of the periodontal host defense system and alveolar bone homeostasis
Published in Molecular oral microbiology (01-06-2016)“…Summary Aggregatibacter actinomycetemcomitans is a perio‐pathogenic bacteria that has long been associated with localized aggressive periodontitis. The…”
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Journal Article -
2
A systematic review of the content and delivery of education in pulmonary rehabilitation programmes
Published in Respiratory medicine (01-12-2018)“…Pulmonary rehabilitation (PR) is a core component of Chronic Obstructive Pulmonary Disease (COPD) management with well recognized benefits. While suggestions…”
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3
Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
Published in Cell death & disease (11-09-2018)“…In view of the prevalence of sensorineural hearing defects in an ageing population, the development of protocols to generate cochlear hair cells and their…”
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4
Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo
Published in Journal of periodontal research (01-04-2011)“…Guimarães MR, Coimbra LS, de Aquino SG, Spolidorio LC, Kirkwood KL, Rossa C Jr. Potent anti‐inflammatory effects of systemically administered curcumin modulate…”
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5
Metabolic and Aging Influence on Anticancer Immunity in Oral Cancer
Published in Journal of Dental Research (01-09-2024)“…The average age and obesity prevalence are increasing globally. Both aging and metabolic disease burden increase the risk of oral squamous cell carcinoma…”
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Book Review Journal Article -
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Sexual Dimorphism in Immunity to Oral Bacterial Diseases: Intersection of Neutrophil and Osteoclast Pathobiology
Published in Journal of Dental Research (01-12-2018)“…Sex is a biological variable that affects immune responses to bacterial and other types of infectious agents. Males and females are known to have differential…”
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Book Review Journal Article -
7
Novel Preosteoclast Populations in Obesity-Associated Periodontal Disease
Published in Journal of dental research (01-03-2022)“…Although there is a clear relationship between the degree of obesity and periodontal disease incidence, the mechanisms that underpin the links between these…”
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8
Metabolic Syndrome Exacerbates Inflammation and Bone Loss in Periodontitis
Published in Journal of dental research (01-02-2015)“…Clinical studies have shown that metabolic syndrome (MetS) is associated with increased risk of developing periodontitis. However, the underlying mechanisms…”
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9
Women's participation in decision‐making: Analysis of Bangladesh Demographic and Health Survey data 2017–2018
Published in Journal of international development (01-01-2024)“…Gender‐based inequities prevent women from partaking in decision‐making. This study is a secondary analysis of the 2017–2018 Bangladesh Demographic and Health…”
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10
MAP Kinase Phosphatase-1 Protects against Inflammatory Bone Loss
Published in Journal of dental research (01-12-2009)“…The mitogen-activated protein (MAP) kinase phosphatase (MKP) family plays an important function in regulating the pro-inflammatory cytokines by deactivating…”
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11
Topical Vitamin D Prevents Bone Loss and Inflammation in a Mouse Model
Published in Journal of dental research (01-08-2024)“…There is a strong association between vitamin D levels and periodontal disease based on numerous epidemiological studies. We have previously shown that…”
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12
CXCL13 activation of c-Myc induces RANK ligand expression in stromal/preosteoblast cells in the oral squamous cell carcinoma tumor–bone microenvironment
Published in Oncogene (03-01-2013)“…CXC chemokine ligand-13 (CXCL13) has been implicated in oral squamous cell carcinoma (OSCC) tumor progression and osteolysis. The tumor necrosis factor family…”
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13
Emerging infectious disease leads to rapid population declines of common British birds
Published in PloS one (18-08-2010)“…Emerging infectious diseases are increasingly cited as threats to wildlife, livestock and humans alike. They can threaten geographically isolated or critically…”
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14
Control of Cytokine mRNA Expression by RNA-binding Proteins and microRNAs
Published in Journal of dental research (01-07-2012)“…Cytokines are critical mediators of inflammation and host defenses. Regulation of cytokines can occur at various stages of gene expression, including…”
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15
Efficacy of screening in preventing cervical cancer among older women
Published in Cancer causes & control (01-09-2013)“…Background: Although the effectiveness of cervical cancer screening has been firmly established in reproductive-age women, its usefulness in older women is…”
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16
Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells
Published in Frontiers in cellular neuroscience (13-09-2019)“…Aminoglycoside antibiotics are widely prescribed to treat a variety of serious bacterial infections. They are extremely useful clinical tools, but have adverse…”
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17
Epidemiological evidence that garden birds are a source of human salmonellosis in England and Wales
Published in PloS one (26-02-2014)“…The importance of wild bird populations as a reservoir of zoonotic pathogens is well established. Salmonellosis is a frequently diagnosed infectious cause of…”
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18
Multistep redirection by cross-beam power transfer of ultrahigh-power lasers in a plasma
Published in Nature physics (01-04-2012)“…Laser redirection by cross-beam power transfer in a plasma is an important example of a nonlinear optics process which uses laser–plasma instabilities to one’s…”
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19
d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity
Published in Frontiers in cellular neuroscience (05-09-2017)“…Aminoglycoside antibiotics are widely used for the treatment of life-threatening bacterial infections, but cause permanent hearing loss in a substantial…”
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20
CD36 is upregulated in mice with periodontitis and metabolic syndrome and involved in macrophage gene upregulation by palmitate
Published in Oral diseases (01-03-2017)“…Background We reported that high‐fat diet (HFD)‐induced metabolic syndrome (MetS) exacerbates lipopolysaccharide (LPS)‐stimulated periodontitis and palmitate,…”
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