Search Results - "KIRKNESS, Jason P"

The effect of increased lung volume in chronic obstructive pulmonary disease on upper airway obstruction during sleep by Biselli, Paolo, Grossman, Peter R, Kirkness, Jason P, Patil, Susheel P, Smith, Philip L, Schwartz, Alan R, Schneider, Hartmut

“…Patients with chronic obstructive pulmonary disease (COPD) exhibit increases in lung volume due to expiratory airflow limitation. Increases in lung volumes may…”
Get full text

Quantifying ventilation by X-ray velocimetry in healthy adults by Siddharthan, Trishul, Grealis, Kyle, Kirkness, Jason P, Ötvös, Tamás, Stefanovski, Darko, Tombleson, Alex, Dalzell, Molly, Gonzalez, Ernesto, Nakrani, Kinjal Bhatt, Wenger, David, Lester, Michael G, Richmond, Bradley W, Fouras, Andreas, Punjabi, Naresh M

“…X-ray velocimetry (XV) has been utilized in preclinical models to assess lung motion and regional ventilation, though no studies have compared XV-derived…”
Get full text

Evolution of Changes in Upper Airway Collapsibility during Slow Induction of Anesthesia with Propofol by HILLMAN, David R, WALSH, Jennifer H, MADDISON, Kathleen J, PLATT, Peter R, KIRKNESS, Jason P, NOFFSINGER, William J, EASTWOOD, Peter R

“…Upper airway collapsibility is known to increase under anesthesia. This study assessed how this increase in collapsibility evolves during slow Propofol…”
Get full text

Sleep and Respiratory Physiology in Adults by Sowho, Mudiaga, MD, MPH, Amatoury, Jason, MBiomedE, PhD, Kirkness, Jason P., PhD, Patil, Susheel P., MD, PhD

“…Respiration during sleep is determined by metabolic demand; respiratory drive is determined by a central respiratory generator. Changes in pharyngeal dilator…”
Get full text

Effect of end-expiratory lung volume on upper airway collapsibility in sleeping men and women by SQUIER, Samuel B, PATIL, Susheel P, SCHNEIDER, Hartmut, KIRKNESS, Jason P, SMITH, Philip L, SCHWARTZ, Alan R

“…The relationship between changes in absolute end-expiratory lung volume (EELV) and collapsibility has not been rigorously quantified. We hypothesized that…”
Get full text

Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health by Trembley, Janeen H, Barach, Paul, Tomáška, Julie M, Poole, Jedidah T, Ginex, Pamela K, Miller, Robert F, Lindheimer, Jacob B, Szema, Anthony M, Gandy, Kimberly, Siddharthan, Trishul, Kirkness, Jason P, Nixon, Joshua P, Torres, Rosie Lopez, Klein, Mark A, Nurkiewicz, Timothy R, Butterick, Tammy A

“…Millions of United States (U.S.) troops deployed to the Middle East and Southwest Asia were exposed to toxic airborne hazards and/or open-air burn pits. Burn…”
Get full text

Obesity and upper airway control during sleep by Schwartz, Alan R, Patil, Susheel P, Squier, Samuel, Schneider, Hartmut, Kirkness, Jason P, Smith, Philip L

“…Sleep Disorders Center, Johns Hopkins School of Medicine, Baltimore, Maryland Submitted 18 August 2009 ; accepted in final form 27 October 2009 Mechanisms…”
Get full text

Effects of leptin and obesity on the upper airway function by Polotsky, Mikhael, Elsayed-Ahmed, Ahmed S, Pichard, Luis, Harris, Christopher C, Smith, Philip L, Schneider, Hartmut, Kirkness, Jason P, Polotsky, Vsevolod, Schwartz, Alan R

“…Obesity is associated with alterations in upper airway collapsibility during sleep. Obese, leptin-deficient mice demonstrate blunted ventilatory control,…”
Get full text

Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleep by Kirkness, Jason P, Schwartz, Alan R, Schneider, Hartmut, Punjabi, Naresh M, Maly, Joseph J, Laffan, Alison M, McGinley, Brian M, Magnuson, Thomas, Schweitzer, Michael, Smith, Philip L, Patil, Susheel P

“…1 Division of Pulmonary and Critical Care Medicine and 2 Department of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland; and 3 Western Australia…”
Get full text

Association of x-ray velocimetry (XV) ventilation analysis compared to spirometry by Kirkness, Jason P, Dusting, Jonathan, Eikelis, Nina, Pirakalathanan, Piraveen, DeMarco, John, Shiao, Stephen L, Fouras, Andreas

“…X-ray Velocimetry (XV) ventilation analysis is a 4-dimensional imaging-based method for quantifying regional ventilation, aiding in the assessment of lung…”
Get full text

Leptin and the control of pharyngeal patency during sleep in severe obesity by Shapiro, Steven D, Chin, Chien-Hung, Kirkness, Jason P, McGinley, Brian M, Patil, Susheel P, Polotsky, Vsevolod Y, Biselli, Paolo Jose Cesare, Smith, Philip L, Schneider, Hartmut, Schwartz, Alan R

“…Obesity imposes mechanical loads on the upper airway, resulting in flow limitation and obstructive sleep apnea (OSA). In previous animal models, leptin has…”
Get full text

Compensatory responses to upper airway obstruction in obese apneic men and women by Chin, Chien-Hung, Kirkness, Jason P, Patil, Susheel P, McGinley, Brian M, Smith, Philip L, Schwartz, Alan R, Schneider, Hartmut

“…Defective structural and neural upper airway properties both play a pivotal role in the pathogenesis of obstructive sleep apnea. A more favorable structural…”
Get full text

Sleep disordered breathing in Marfan syndrome: Value of standard screening questionnaires by Sowho, Mudiaga O., Patil, Susheel, Schneider, Hartmut, MacCarrick, Gretchen, Kirkness, Jason P., Wolfe, Lisa F., Sterni, Laura, Cistulli, Peter A., Neptune, Enid R.

“…Background A high prevalence of sleep disordered breathing (SDB) has been reported in persons with Marfan syndrome (MFS), a single gene disorder of connective…”
Get full text

Obesity-related ventilatory phenotypes of sleep-disordered breathing by Kirkness, Jason P

Get full text

Relationship between surface tension of upper airway lining liquid and upper airway collapsibility during sleep in obstructive sleep apnea hypopnea syndrome by Kirkness, Jason P, Madronio, Melanie, Stavrinou, Rosie, Wheatley, John R, Amis, Terence C

“…Ludwig Engel Centre for Respiratory Research, Westmead Hospital and University of Sydney, Sydney, New South Wales, Australia 2145 Submitted 9 May 2003 ;…”
Get full text

Influence of breathing route on upper airway lining liquid surface tension in humans by Verma, Manisha, Seto‐Poon, Margaret, Wheatley, John R., Amis, Terence C., Kirkness, Jason P.

“…We have recently demonstrated that the severity of sleep-disordered breathing in obstructive sleep apnoea hypopnoea syndrome (OSAHS) can be reduced by lowering…”
Get full text

Nasal high-flow therapy reduces work of breathing compared with oxygen during sleep in COPD and smoking controls: a prospective observational study by Biselli, Paolo J C, Kirkness, Jason P, Grote, Ludger, Fricke, Kathrin, Schwartz, Alan R, Smith, Philip, Schneider, Hartmut

“…Patients with chronic obstructive pulmonary disease (COPD) endure excessive resistive and elastic loads leading to chronic respiratory failure. Oxygen…”
Get full text

The effects of hormonal status on upper airway patency in normal female subjects during propofol anesthesia by Hoshino, Yuko, DDS, PhD, Ayuse, Takao, DDS, PhD, Kobayashi, Masato, DDS, Kurata, Shinji, DDS, PhD, Kawai, Mari, DDS, Schneider, Hartmut, MD, PhD, Patil, Susheel P., MD, PhD, Schwartz, Alan R., MD, Kirkness, Jason P., PhD, Oi, Kumiko, DDS, PhD

“…Abstract Study Objective To determine the mechanical upper airway properties and compensatory neuromuscular responses to obstruction during propofol anesthesia…”
Get full text

The interplay between tongue tissue volume, hyoid position, and airway patency by Kirkness, Jason P, Sowho, Mudiaga, Murano, Emi

Get full text

Oscillatory pressure wave transmission from the upper airway to the carotid artery by Howitt, Lauren, Kairaitis, Kristina, Kirkness, Jason P, Garlick, Sarah R, Wheatley, John R, Byth, Karen, Amis, Terence C

“…1 Ludwig Engel Centre for Respiratory Research, 2 Westmead Millennium Institute, and 3 University of Sydney, Westmead, New South Wales, Australia Submitted 13…”
Get full text