Search Results - "KIRKNESS, Jason"

Obesity-related ventilatory phenotypes of sleep-disordered breathing by Kirkness, Jason P

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The effect of increased lung volume in chronic obstructive pulmonary disease on upper airway obstruction during sleep by Biselli, Paolo, Grossman, Peter R, Kirkness, Jason P, Patil, Susheel P, Smith, Philip L, Schwartz, Alan R, Schneider, Hartmut

“…Patients with chronic obstructive pulmonary disease (COPD) exhibit increases in lung volume due to expiratory airflow limitation. Increases in lung volumes may…”
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Evolution of Changes in Upper Airway Collapsibility during Slow Induction of Anesthesia with Propofol by HILLMAN, David R, WALSH, Jennifer H, MADDISON, Kathleen J, PLATT, Peter R, KIRKNESS, Jason P, NOFFSINGER, William J, EASTWOOD, Peter R

“…Upper airway collapsibility is known to increase under anesthesia. This study assessed how this increase in collapsibility evolves during slow Propofol…”
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Quantifying ventilation by X-ray velocimetry in healthy adults by Siddharthan, Trishul, Grealis, Kyle, Kirkness, Jason P, Ötvös, Tamás, Stefanovski, Darko, Tombleson, Alex, Dalzell, Molly, Gonzalez, Ernesto, Nakrani, Kinjal Bhatt, Wenger, David, Lester, Michael G, Richmond, Bradley W, Fouras, Andreas, Punjabi, Naresh M

“…X-ray velocimetry (XV) has been utilized in preclinical models to assess lung motion and regional ventilation, though no studies have compared XV-derived…”
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Sleep and Respiratory Physiology in Adults by Sowho, Mudiaga, MD, MPH, Amatoury, Jason, MBiomedE, PhD, Kirkness, Jason P., PhD, Patil, Susheel P., MD, PhD

“…Respiration during sleep is determined by metabolic demand; respiratory drive is determined by a central respiratory generator. Changes in pharyngeal dilator…”
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Nasal high-flow therapy reduces work of breathing compared with oxygen during sleep in COPD and smoking controls: a prospective observational study by Biselli, Paolo J C, Kirkness, Jason P, Grote, Ludger, Fricke, Kathrin, Schwartz, Alan R, Smith, Philip, Schneider, Hartmut

“…Patients with chronic obstructive pulmonary disease (COPD) endure excessive resistive and elastic loads leading to chronic respiratory failure. Oxygen…”
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The interplay between tongue tissue volume, hyoid position, and airway patency by Kirkness, Jason P, Sowho, Mudiaga, Murano, Emi

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Effect of end-expiratory lung volume on upper airway collapsibility in sleeping men and women by SQUIER, Samuel B, PATIL, Susheel P, SCHNEIDER, Hartmut, KIRKNESS, Jason P, SMITH, Philip L, SCHWARTZ, Alan R

“…The relationship between changes in absolute end-expiratory lung volume (EELV) and collapsibility has not been rigorously quantified. We hypothesized that…”
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Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health by Trembley, Janeen H, Barach, Paul, Tomáška, Julie M, Poole, Jedidah T, Ginex, Pamela K, Miller, Robert F, Lindheimer, Jacob B, Szema, Anthony M, Gandy, Kimberly, Siddharthan, Trishul, Kirkness, Jason P, Nixon, Joshua P, Torres, Rosie Lopez, Klein, Mark A, Nurkiewicz, Timothy R, Butterick, Tammy A

“…Millions of United States (U.S.) troops deployed to the Middle East and Southwest Asia were exposed to toxic airborne hazards and/or open-air burn pits. Burn…”
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Localizing Effects of Leptin on Upper Airway and Respiratory Control during Sleep by Yao, Qiaoling, Pho, Huy, Kirkness, Jason, Ladenheim, Ellen E, Bi, Sheng, Moran, Timothy H, Fuller, David D, Schwartz, Alan R, Polotsky, Vsevolod Y

“…Obesity hypoventilation and obstructive sleep apnea are common complications of obesity linked to defects in respiratory pump and upper airway neural control…”
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Obesity and upper airway control during sleep by Schwartz, Alan R, Patil, Susheel P, Squier, Samuel, Schneider, Hartmut, Kirkness, Jason P, Smith, Philip L

“…Sleep Disorders Center, Johns Hopkins School of Medicine, Baltimore, Maryland Submitted 18 August 2009 ; accepted in final form 27 October 2009 Mechanisms…”
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Effects of leptin and obesity on the upper airway function by Polotsky, Mikhael, Elsayed-Ahmed, Ahmed S, Pichard, Luis, Harris, Christopher C, Smith, Philip L, Schneider, Hartmut, Kirkness, Jason P, Polotsky, Vsevolod, Schwartz, Alan R

“…Obesity is associated with alterations in upper airway collapsibility during sleep. Obese, leptin-deficient mice demonstrate blunted ventilatory control,…”
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Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleep by Kirkness, Jason P, Schwartz, Alan R, Schneider, Hartmut, Punjabi, Naresh M, Maly, Joseph J, Laffan, Alison M, McGinley, Brian M, Magnuson, Thomas, Schweitzer, Michael, Smith, Philip L, Patil, Susheel P

“…1 Division of Pulmonary and Critical Care Medicine and 2 Department of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland; and 3 Western Australia…”
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Association of x-ray velocimetry (XV) ventilation analysis compared to spirometry by Kirkness, Jason P, Dusting, Jonathan, Eikelis, Nina, Pirakalathanan, Piraveen, DeMarco, John, Shiao, Stephen L, Fouras, Andreas

“…X-ray Velocimetry (XV) ventilation analysis is a 4-dimensional imaging-based method for quantifying regional ventilation, aiding in the assessment of lung…”
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Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea by McGinley, Brian M, Schwartz, Alan R, Schneider, Hartmut, Kirkness, Jason P, Smith, Philip L, Patil, Susheel P

“…Johns Hopkins Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland Submitted 14 November…”
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Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure by Nilius, Georg, Franke, Karl-Josef, Domanski, Ulrike, Rühle, Karl-Heinz, Kirkness, Jason P, Schneider, Hartmut

“…High flow nasal insufflations (NI) can improve gas exchange and alleviate dyspnea in patients with acute respiratory failure. In the present study we…”
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Hypopnea: ‘rule of thumb’ or ruler and plumb? by Kirkness, Jason P.

“…The controversy that surrounds the definition of hypopnea springs from a contrast between symptomatology and clinical significance that may not be fully…”
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Leptin and the control of pharyngeal patency during sleep in severe obesity by Shapiro, Steven D, Chin, Chien-Hung, Kirkness, Jason P, McGinley, Brian M, Patil, Susheel P, Polotsky, Vsevolod Y, Biselli, Paolo Jose Cesare, Smith, Philip L, Schneider, Hartmut, Schwartz, Alan R

“…Obesity imposes mechanical loads on the upper airway, resulting in flow limitation and obstructive sleep apnea (OSA). In previous animal models, leptin has…”
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A Nasal Cannula Can Be Used to Treat Obstructive Sleep Apnea by McGinley, Brian M, Patil, Susheel P, Kirkness, Jason P, Smith, Philip L, Schwartz, Alan R, Schneider, Hartmut

“…Obstructive sleep apnea syndrome is due to upper airway obstruction and is associated with increased morbidity. Although continuous positive airway pressure…”
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Compensatory responses to upper airway obstruction in obese apneic men and women by Chin, Chien-Hung, Kirkness, Jason P, Patil, Susheel P, McGinley, Brian M, Smith, Philip L, Schwartz, Alan R, Schneider, Hartmut

“…Defective structural and neural upper airway properties both play a pivotal role in the pathogenesis of obstructive sleep apnea. A more favorable structural…”
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