Search Results - "KIRCH, D. G"

Infection and Autoimmunity as Etiologic Factors in Schizophrenia: A Review and Reappraisal by Kirch, Darrell G.

“…The focus of schizophrenia research has been turning from studies of structural and functional brain abnormalities to an increasing emphasis on possible…”
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Polydipsia and hyponatremia in psychiatric patients by Illowsky, B P, Kirch, D G

“…Many psychiatric patients have polydipsia and polyuria without identifiable underlying medical causes. Hyponatremia develops in some polydipsic patients and…”
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When Symptoms Persist: Choosing Among Alternative Somatic Treatments for Schizophrenia by Christison, George W, Kirch, Darrell G, Wyatt, Richard Jed

“…Many patients with schizophrenia continue to have significant disabling symptoms despite adequate trials of different types and doses of traditional…”
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Diagnostic accuracy and confusability analyses: an application to the Diagnostic Interview for Genetic Studies by Faraone, S V, Blehar, M, Pepple, J, Moldin, S O, Norton, J, Nurnberger, J I, Malaspina, D, Kaufmann, C A, Reich, T, Cloninger, C R, DePaulo, J R, Berg, K, Gershon, E S, Kirch, D G, Tsuang, M T

“…The dominant, contemporary paradigm for developing and refining diagnoses relies heavily on assessing reliability with kappa coefficients and virtually ignores…”
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Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationships to levels of other aminergic transmitters and ratings of symptoms by Prell, George D., Green, Jack Peter, Kaufmann, Charles A., Khandelwal, Jai K., Morrishow, Albert M., Kirch, Darrell G., Linnoila, Markku, Wyatt, Richard Jed

“…Levels of the histamine metabolites, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), and metabolites of other aminergic transmitters…”
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CSF IL-1 and IL-2 in medicated schizophrenic patients and normal volunteers by Rapaport, Mark Hyman, McAllister, Cathy G., Pickar, David, Tamarkin, Lawrence, Kirch, Darrell G., Paul, Stephen M.

“…It is clear that cytokines exert a variety of modulatory actions on the central nervous system. As part of our work exploring the relationship between immune…”
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Translational careers by Andrews, N, Burris, J E, Cech, T R, Coller, B S, Crowley, Jr, W F, Gallin, E K, Kelner, K L, Kirch, D G, Leshner, A I, Morris, C D, Nguyen, F T, Oates, J, Sung, N S

“…Powered by the computational muscle of bioinformatics and the broad perspective of systems biology, advances in biomedical science now have the capacity to…”
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Cerebrospinal fluid oxytocin concentration in schizophrenic patients does not differ from control subjects and is not changed by neuroleptic medication by Glovinsky, D, Kalogeras, K T, Kirch, D G, Suddath, R, Wyatt, R J

“…Cerebrospinal fluid (CSF) oxytocin concentrations in 20 neuroleptic-treated schizophrenic patients, 31 neuroleptic-withdrawn schizophrenic patients, and 15…”
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Impact of minority physicians on health care by THURMOND, V. B, KIRCH, D. G

“…There is concern that anti-affirmative-action measures will negate gains made ill educating underrepresented minority physicians and that this…”
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MRI Changes During Water Loading in Patients With Polydipsia and Intermittent Hyponatremia by Leadbetter, Robert A., Shutty, Jr, Michael S., Elkashef, Ahmed M., Kirch, Darrell G., Spraggins, Thomas, Cail, Wayne S., Wu, Houwei, Bilder, Robert M., Lieberman, Jeffery A., Wyatt, Richard Jed

“…OBJECTIVE: Patients with polydipsia and intermittent hyponatremia have greater ventricle-brain ratios (VBRs) than matched patients without polydipsia and…”
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Research on First-Episode Psychosis: Report on a National Institute of Mental Health Workshop by Kirch, Darrell G, Keith, Samuel J, Matthews, Susan M

“…The need to focus increased research on patients experiencing their first episode of psychosis was emphasized in A National Plan for Schizophrenia Research. To…”
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Blood-CSF barrier permeability and central nervous system immunoglobulin G in schizophrenia by KIRCH, D. G, ALEXANDER, R. C, SUDDATH, R. L, PAPADOPOULOS, N. M, KAUFMANN, C. A, DANIEL, D. G, WYATT, R. J

“…The ratio of albumin in cerebrospinal fluid (CSF) to serum may serve as an index of the integrity of the blood-CSF barrier, with increases in this ratio…”
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Search for evidence of herpes simplex virus, type 1, or varicella-zoster virus infection in postmortem brain tissue from schizophrenic patients by Alexander, R C, Cabirac, G, Lowenkopf, T, Casanova, M, Kleinman, J, Wyatt, R J, Kirch, D G

“…The highly sensitive polymerase chain reaction (PCR) was used to search for herpes simplex virus type 1 (HSV-I) or varicella-zoster virus (VZV) in the DNA…”
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Early antipsychotic response to resumption of neuroleptics in drug-free chronic schizophrenic patients by Glovinsky, D, Kirch, D G, Wyatt, R J

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Effects of chronic cocaine treatment on rat brain: long-term reduction in frontal cortical serotonin by Egan, M F, Wing, L, Li, R, Kirch, D G, Wyatt, R J

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Polydipsia and chronic hyponatremia in schizophrenic inpatients by KIRCH, D. G, BIGELOW, L. B, WEINBERGER, D. R, LAWSON, W. B, WYATT, R. J

“…The occasional presence of polydipsia in psychiatric patients, at times progressing to hyponatremia with severe medical complications, has been previously…”
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Effects of haloperidol, lithium, and valproate on phosphoinositide turnover in rat brain by Li, R, Wing, L L, Wyatt, R J, Kirch, D G

“…The effects of acute, subacute, and chronic treatment with haloperidol, lithium, and valproate on inositol phosphate (IP) formation were examined. Acute…”
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A double blind, placebo-controlled trial of demeclocycline treatment of polydipsia-hyponatremia in chronically psychotic patients by Alexander, R C, Karp, B I, Thompson, S, Khot, V, Kirch, D G

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Hypothesis: a nicotine-dopamine interaction linking smoking with Parkinson's disease and tardive dyskinesia by KIRCH, D. G, ALHO, A.-M, WYATT, R. J

“…1. Nicotine, an important pharmacological component of cigarette smoke, is known to have significant effects on central nervous system (CNS) dopaminergic…”
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The nucleus basalis of Meynert, senile plaques, and intellectual impairment in schizophrenia by el-Mallakh, R S, Kirch, D G, Shelton, R, Fan, K J, Pezeshkpour, G, Kanhouwa, S, Wyatt, R J, Kleinman, J E

“…The large, hyperchromic, cholinergic neurons of the nucleus basalis of Meynert (nbM) and the presence of senile plaques were quantified in postmortem brain…”
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