The seroprevalence of parvovirus B19 infection in pregnant women in Sudan

The seroprevalence of parvovirus B19 infection in pregnant women in Sudan

Parvovirus B19 (B19V) infection during pregnancy may have serious consequences like fetal anaemia, hydrops fetalis, and fetal loss. Since epidemiological data on B19V infection are generally lacking in Sudan, the current study aimed to determine the seroprevalence of B19V in Sudanese pregnant women....

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Bibliographic Details
Published in:Epidemiology and infection Vol. 143; no. 2; pp. 242 - 248
Main Authors: ADAM, O., MAKKAWI, T., REBER, U., KIRBERG, H., EIS-HÜBINGER, A. M.
Format: Journal Article
Language:English
Published: Cambridge, UK Cambridge University Press 01-01-2015
Subjects:
Adolescent
Adult
Anemia
Antibodies, Viral - blood
Antigens
Cross-Sectional Studies
Displaced persons
DNA, Viral - blood
Education
Epidemiology
Female
Female Infections
Gestational age
Humans
Illiteracy
Immunoglobulin G - blood
Immunoglobulin M - blood
Infections
Original Papers
Parvoviridae Infections - epidemiology
Parvovirus B19
Parvovirus B19, Human
Polymerase Chain Reaction
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Risk Factors
Seroepidemiologic Studies
Serology
Socioeconomic Factors
Statistical analysis
Sudan - epidemiology
Womens health
Young Adult
Sudan
United States > US
Germany
Sudan, Khartoum
seroprevalence
pregnant women
Parvovirus B19
Sudan
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Summary:Parvovirus B19 (B19V) infection during pregnancy may have serious consequences like fetal anaemia, hydrops fetalis, and fetal loss. Since epidemiological data on B19V infection are generally lacking in Sudan, the current study aimed to determine the seroprevalence of B19V in Sudanese pregnant women. Five hundred women, attending antenatal clinics in Khartoum state between November 2008 and March 2009, were enrolled and screened for B19V IgG and IgM antibodies by enzyme immunoassays. The study revealed a B19V IgG seroprevalence of 61·4%, with one subject positive for IgM. B19V DNA was not detected by PCR in any of the tested individuals. B19V IgG seroprevalence was significantly correlated with multigravidity (P = 0·046). Our data showed that B19V infection is prevalent in Sudan and we recommend further studies in Sudanese women, particularly in those with complications and adverse outcomes of pregnancy.
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ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268814000600